메뉴 건너뛰기




Volumn 95, Issue PART 2, 2014, Pages 363-372

Pharmacological disruption of hepatitis C NS5A protein intra- and intermolecular conformations

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DACLATASVIR; GSK 2336805; NONSTRUCTURAL PROTEIN 5A; UNCLASSIFIED DRUG;

EID: 84892588133     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.054569-0     Document Type: Article
Times cited : (12)

References (32)
  • 1
    • 0037140742 scopus 로고    scopus 로고
    • New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: Synthesis and biological applications
    • Adams, S. R., Campbell, R. E., Gross, L. A., Martin, B. R., Walkup, G. K., Yao, Y., Llopis, J. & Tsien, R. Y. (2002). New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications. J Am Chem Soc 124, 6063-6076.
    • (2002) J Am Chem Soc , vol.124 , pp. 6063-6076
    • Adams, S.R.1    Campbell, R.E.2    Gross, L.A.3    Martin, B.R.4    Walkup, G.K.5    Yao, Y.6    Llopis, J.7    Tsien, R.Y.8
  • 2
    • 84871891911 scopus 로고    scopus 로고
    • Subtype specific differences in NS5A domain II reveals involvement of proline at position 310 in cyclosporine susceptibility of hepatitis C virus
    • Ansari, I. U. & Striker, R. T. (2012). Subtype specific differences in NS5A domain II reveals involvement of proline at position 310 in cyclosporine susceptibility of hepatitis C virus. Viruses 4, 3303-3315.
    • (2012) Viruses , vol.4 , pp. 3303-3315
    • Ansari, I.U.1    Striker, R.T.2
  • 3
    • 84872683862 scopus 로고    scopus 로고
    • Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility
    • Ansari, I. U., Allen, T., Berical, A., Stock, P. G., Barin, B. & Striker, R. (2013). Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility. Virology 436, 268-273.
    • (2013) Virology , vol.436 , pp. 268-273
    • Ansari, I.U.1    Allen, T.2    Berical, A.3    Stock, P.G.4    Barin, B.5    Striker, R.6
  • 5
    • 84864386121 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer-based intracellular assay for the conformation of hepatitis C virus drug target NS5A
    • Bhattacharya, D., Ansari, I. H., Mehle, A. & Striker, R. (2012). Fluorescence resonance energy transfer-based intracellular assay for the conformation of hepatitis C virus drug target NS5A. J Virol 86, 8277-8286.
    • (2012) J Virol , vol.86 , pp. 8277-8286
    • Bhattacharya, D.1    Ansari, I.H.2    Mehle, A.3    Striker, R.4
  • 6
    • 0037370622 scopus 로고    scopus 로고
    • Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture
    • Blight, K. J., McKeating, J. A., Marcotrigiano, J. & Rice, C. M. (2003). Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. J Virol 77, 3181-3190.
    • (2003) J Virol , vol.77 , pp. 3181-3190
    • Blight, K.J.1    McKeating, J.A.2    Marcotrigiano, J.3    Rice, C.M.4
  • 8
    • 33745260979 scopus 로고    scopus 로고
    • Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells
    • Das, S. C., Nayak, D., Zhou, Y. & Pattnaik, A. K. (2006). Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells. J Virol 80, 6368-6377.
    • (2006) J Virol , vol.80 , pp. 6368-6377
    • Das, S.C.1    Nayak, D.2    Zhou, Y.3    Pattnaik, A.K.4
  • 9
    • 9144257569 scopus 로고    scopus 로고
    • Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
    • Enomoto, N., Sakuma, I., Asahina, Y., Kurosaki, M., Murakami, T., Yamamoto, C., Ogura, Y., Izumi, N., Marumo, F. & Sato, C. (1996). Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 334, 77-82.
    • (1996) N Engl J Med , vol.334 , pp. 77-82
    • Enomoto, N.1    Sakuma, I.2    Asahina, Y.3    Kurosaki, M.4    Murakami, T.5    Yamamoto, C.6    Ogura, Y.7    Izumi, N.8    Marumo, F.9    Sato, C.10
  • 10
    • 77956028043 scopus 로고    scopus 로고
    • All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding
    • Foster, T. L., Belyaeva, T., Stonehouse, N. J., Pearson, A. R. & Harris, M. (2010). All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding. J Virol 84, 9267-9277.
    • (2010) J Virol , vol.84 , pp. 9267-9277
    • Foster, T.L.1    Belyaeva, T.2    Stonehouse, N.J.3    Pearson, A.R.4    Harris, M.5
  • 11
    • 82455192239 scopus 로고    scopus 로고
    • Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: In vitro and in vivo correlations
    • other authors
    • Fridell, R. A., Wang, C., Sun, J. H., O'Boyle, D. R., II, Nower, P., Valera, L., Qiu, D., Roberts, S., Huang, X. & other authors (2011). Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology 54, 1924-1935.
    • (2011) Hepatology , vol.54 , pp. 1924-1935
    • Fridell, R.A.1    Wang, C.2    Sun, J.H.3    O'Boyle II, D.R.4    Nower, P.5    Valera, L.6    Qiu, D.7    Roberts, S.8    Huang, X.9
  • 13
    • 80053339008 scopus 로고    scopus 로고
    • An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases
    • American Association for Study of Liver Diseases
    • Ghany, M. G., Nelson, D. R., Strader, D. B., Thomas, D. L., Seeff, L. B. & American Association for Study of Liver Diseases (2011). An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 54, 1433-1444.
    • (2011) Hepatology , vol.54 , pp. 1433-1444
    • Ghany, M.G.1    Nelson, D.R.2    Strader, D.B.3    Thomas, D.L.4    Seeff, L.B.5
  • 15
    • 78649430973 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural protein 5A: Biochemical characterization of a novel structural class of RNA-binding proteins
    • Hwang, J., Huang, L., Cordek, D. G., Vaughan, R., Reynolds, S. L., Kihara, G., Raney, K. D., Kao, C. C. & Cameron, C. E. (2010). Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. J Virol 84, 12480-12491.
    • (2010) J Virol , vol.84 , pp. 12480-12491
    • Hwang, J.1    Huang, L.2    Cordek, D.G.3    Vaughan, R.4    Reynolds, S.L.5    Kihara, G.6    Raney, K.D.7    Kao, C.C.8    Cameron, C.E.9
  • 16
    • 79955532870 scopus 로고    scopus 로고
    • The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein
    • Lee, C., Ma, H., Hang, J. Q., Leveque, V., Sklan, E. H., Elazar, M., Klumpp, K. & Glenn, J. S. (2011). The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein. Virology 414, 10-18.
    • (2011) Virology , vol.414 , pp. 10-18
    • Lee, C.1    Ma, H.2    Hang, J.Q.3    Leveque, V.4    Sklan, E.H.5    Elazar, M.6    Klumpp, K.7    Glenn, J.S.8
  • 18
    • 0037369066 scopus 로고    scopus 로고
    • Viral and cellular determinants of hepatitis C virus RNA replication in cell culture
    • Lohmann, V., Hoffmann, S., Herian, U., Penin, F. & Bartenschlager, R. (2003). Viral and cellular determinants of hepatitis C virus RNA replication in cell culture. J Virol 77, 3007-3019.
    • (2003) J Virol , vol.77 , pp. 3007-3019
    • Lohmann, V.1    Hoffmann, S.2    Herian, U.3    Penin, F.4    Bartenschlager, R.5
  • 20
    • 66149115122 scopus 로고    scopus 로고
    • Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus
    • Love, R. A., Brodsky, O., Hickey, M. J., Wells, P. A. & Cronin, C. N. (2009). Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus. J Virol 83, 4395-4403.
    • (2009) J Virol , vol.83 , pp. 4395-4403
    • Love, R.A.1    Brodsky, O.2    Hickey, M.J.3    Wells, P.A.4    Cronin, C.N.5
  • 21
    • 84870051464 scopus 로고    scopus 로고
    • Cyclophilin inhibitors for hepatitis C therapy
    • Membreno, F. E., Espinales, J. C. & Lawitz, E. J. (2013). Cyclophilin inhibitors for hepatitis C therapy. Clin Liver Dis 17, 129-139.
    • (2013) Clin Liver Dis , vol.17 , pp. 129-139
    • Membreno, F.E.1    Espinales, J.C.2    Lawitz, E.J.3
  • 22
    • 0034581516 scopus 로고    scopus 로고
    • Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein
    • Miyawaki, A. & Tsien, R. Y. (2000). Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein. Methods Enzymol 327, 472-500.
    • (2000) Methods Enzymol , vol.327 , pp. 472-500
    • Miyawaki, A.1    Tsien, R.Y.2
  • 25
    • 80053951840 scopus 로고    scopus 로고
    • The effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization
    • other authors
    • Qiu, D., Lemm, J. A., O'Boyle, D. R., II, Sun, J. H., Nower, P. T., Nguyen, V., Hamann, L. G., Snyder, L. B., Deon, D. H. & other authors (2011). The effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization. J Gen Virol 92, 2502-2511.
    • (2011) J Gen Virol , vol.92 , pp. 2502-2511
    • Qiu, D.1    Lemm, J.A.2    O'Boyle II, D.R.3    Sun, J.H.4    Nower, P.T.5    Nguyen, V.6    Hamann, L.G.7    Snyder, L.B.8    Deon, D.H.9
  • 26
    • 52449124695 scopus 로고    scopus 로고
    • NS5A-from obscurity to new target for HCV therapy
    • Schmitz, U. & Tan, S. L. (2008). NS5A-from obscurity to new target for HCV therapy. Recent Pat Antiinfect Drug Discov 3, 77-92.
    • (2008) Recent Pat Antiinfect Drug Discov , vol.3 , pp. 77-92
    • Schmitz, U.1    Tan, S.L.2
  • 27
    • 84870024853 scopus 로고    scopus 로고
    • HCV NS5A inhibitors in development
    • Suk-Fong Lok, A. (2013). HCV NS5A inhibitors in development. Clin Liver Dis 17, 111-121.
    • (2013) Clin Liver Dis , vol.17 , pp. 111-121
    • Suk-Fong Lok, A.1
  • 28
    • 80051826152 scopus 로고    scopus 로고
    • Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: Insights into compound modes of action
    • other authors
    • Targett-Adams, P., Graham, E. J., Middleton, J., Palmer, A., Shaw, S. M., Lavender, H., Brain, P., Tran, T. D., Jones, L. H. & other authors (2011). Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action. J Virol 85, 6353-6368.
    • (2011) J Virol , vol.85 , pp. 6353-6368
    • Targett-Adams, P.1    Graham, E.J.2    Middleton, J.3    Palmer, A.4    Shaw, S.M.5    Lavender, H.6    Brain, P.7    Tran, T.D.8    Jones, L.H.9
  • 29
    • 19644393931 scopus 로고    scopus 로고
    • Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
    • Tellinghuisen, T. L., Marcotrigiano, J. & Rice, C. M. (2005). Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435, 374-379.
    • (2005) Nature , vol.435 , pp. 374-379
    • Tellinghuisen, T.L.1    Marcotrigiano, J.2    Rice, C.M.3
  • 30
    • 42949145532 scopus 로고    scopus 로고
    • Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
    • Tellinghuisen, T. L., Foss, K. L. & Treadaway, J. C. (2008). Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog 4, e1000032.
    • (2008) PLoS Pathog , vol.4
    • Tellinghuisen, T.L.1    Foss, K.L.2    Treadaway, J.C.3
  • 31
    • 0026725397 scopus 로고
    • Electroporation in 'intracellular' buffer increases cell survival
    • van den Hoff, M. J., Moorman, A. F. & Lamers, W. H. (1992). Electroporation in 'intracellular' buffer increases cell survival. Nucleic Acids Res 20, 2902.
    • (1992) Nucleic Acids Res , vol.20 , pp. 2902
    • van den Hoff, M.J.1    Moorman, A.F.2    Lamers, W.H.3
  • 32
    • 1642288430 scopus 로고    scopus 로고
    • WHO, World Health Organization, Geneva, Switzerland
    • WHO (2011). Hepatitis C. Fact sheet no. 164. World Health Organization, Geneva, Switzerland.
    • (2011) Hepatitis C. Fact sheet no. 164


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.