메뉴 건너뛰기




Volumn 4, Issue 12, 2012, Pages 3303-3315

Subtype specific differences in NS5A domain II reveals involvement of proline at position 310 in cyclosporine susceptibility of hepatitis C virus

Author keywords

Cyclophilin; Cyclosporine; Hepatitis C virus; Susceptibility

Indexed keywords

ALANINE; CYCLOSPORIN; GREEN FLUORESCENT PROTEIN; NONSTRUCTURAL PROTEIN 5A; PROLINE; THREONINE;

EID: 84871891911     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v4123303     Document Type: Article
Times cited : (11)

References (18)
  • 2
    • 36349034692 scopus 로고    scopus 로고
    • Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B
    • Fernandes, F.; Poole, D.S.; Hoover, S.; Middleton, R.; Andrei, A.C.; Gerstner, J.; Striker, R. Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B. Hepatology 2007, 46, 1026-1033.
    • (2007) Hepatology , vol.46 , pp. 1026-1033
    • Fernandes, F.1    Poole, D.S.2    Hoover, S.3    Middleton, R.4    Andrei, A.C.5    Gerstner, J.6    Striker, R.7
  • 4
    • 33748687426 scopus 로고    scopus 로고
    • NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon
    • Ma, S.; Boerner, J.E.; TiongYip, C.; Weidmann, B.; Ryder, N.S.; Cooreman, M.P.; Lin, K. NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon. Antimicrob. Agents Chemother. 2006, 50, 2976-2982.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 2976-2982
    • Ma, S.1    Boerner, J.E.2    TiongYip, C.3    Weidmann, B.4    Ryder, N.S.5    Cooreman, M.P.6    Lin, K.7
  • 6
    • 43949123575 scopus 로고    scopus 로고
    • Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro
    • Yang, F.; Robotham, J.M.; Nelson, H.B.; Irsigler, A.; Kenworthy, R.; Tang, H. Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro. J. Virol. 2008, 82, 5269-5278.
    • (2008) J. Virol. , vol.82 , pp. 5269-5278
    • Yang, F.1    Robotham, J.M.2    Nelson, H.B.3    Irsigler, A.4    Kenworthy, R.5    Tang, H.6
  • 7
    • 79960422127 scopus 로고    scopus 로고
    • Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner
    • Foster, T.L.; Gallay, P.; Stonehouse, N.J.; Harris, M. Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner. J. Virol. 2011, 85, 7460-7464.
    • (2011) J. Virol. , vol.85 , pp. 7460-7464
    • Foster, T.L.1    Gallay, P.2    Stonehouse, N.J.3    Harris, M.4
  • 10
    • 38349162328 scopus 로고    scopus 로고
    • Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein
    • Tellinghuisen, T.L.; Foss, K.L.; Treadaway, J.C.; Rice, C.M. Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein. J. Virol. 2008, 82, 1073-1083.
    • (2008) J. Virol. , vol.82 , pp. 1073-1083
    • Tellinghuisen, T.L.1    Foss, K.L.2    Treadaway, J.C.3    Rice, C.M.4
  • 12
    • 78149361253 scopus 로고    scopus 로고
    • Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A
    • Fernandes, F.; Ansari, I.U.; Striker, R. cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A. PLoS One 2010, 5, e9815.
    • (2010) PLoS One , vol.5
    • Fernandes, F.1    Ansari, I.U.2    Striker, R.3
  • 13
    • 84861303385 scopus 로고    scopus 로고
    • A conserved tandem cyclophilin-binding site in hepatitis C virus nonstructural protein 5A regulates alisporivir susceptibility
    • Grise, H.; Frausto, S.; Logan, T.; Tang, H. A conserved tandem cyclophilin-binding site in hepatitis C virus nonstructural protein 5A regulates alisporivir susceptibility. J. Virol. 2012, 86, 4811-4822.
    • (2012) J. Virol , vol.86 , pp. 4811-4822
    • Grise, H.1    Frausto, S.2    Logan, T.3    Tang, H.4
  • 18
    • 79955815806 scopus 로고    scopus 로고
    • Sustained virological response with 29 days of Debio 025 monotherapy in hepatitis C virus genotype
    • Patel, H.; Heathcote, E.J. Sustained virological response with 29 days of Debio 025 monotherapy in hepatitis C virus genotype 3. Gut 2011, 60, 879.
    • (2011) Gut , vol.60 , pp. 879
    • Patel, H.1    Heathcote, E.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.