Design of an amide N-glycoside derivative of β-glucogallin: A stable, potent, and specific inhibitor of aldose reductase

Journal of Medicinal Chemistry

Volumn 57, Issue 1, 2014, Pages 71-77

  Li, Linfeng ^a   Chang, Kun Che ^a,b   Zhou, Yaming ^a   Shieh, Biehuoy ^b   Ponder, Jessica ^a   Abraham, Adedoyin D ^a   Ali, Hadi ^a   Snow, Anson ^b   Petrash, J Mark ^a,b   Labarbera, Daniel V ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2, 3, 4, 6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYL) 4 (3, 4, 5 TRIBENZYLOXYPHENYL) 1, 2, 3 TRIAZOLE; 1 (BETA DEXTRO GLUCOPYRANOSYL) 4 (3, 4, 5 TRIHYDROXYPHENYL) 1, 2, 3 TRIAZOLE; 1 O GALLOYL BETA DEXTRO GLUCOPYRANOSIDE; 2 (3, 4, 5 TRIBENZYLOXYPHENYL)ETHYL BETA DEXTRO GLUCOPYRANOSIDE; 2 (3, 4, 5 TRIHYDROXYPHENYL)ETHYL BETA DEXTRO GLUCOPYRANOSIDE; 2, 3, 4, 6 TETRA O BENZYL 1 O (TRI O BENZYLGALLOYL) BETA DEXTRO GLUCOPYRANOSE; 3 (3, 4, 5 TRIHYDROXYPHENYL)PROPYL BETA DEXTRO GLUCOPYRANOSIDE; 3, 4, 5 TRIBENZYLOXYCINNAMYL BETA DEXTRO GLUCOPYRANOSIDE; [1 (3, 4, 5 TRIBENZYLOXYBENZYL) 1, 2, 3 TRIAZOLE 4 YL]METHYL 2, 3, 4, 6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSIDE; [1 (3, 4, 5 TRIHYDROXYBENZYL) 1, 2, 3 TRIAZOLE 4 YL]METHYL BETA DEXTRO GLUCOPYRANOSIDE; ALDOSE REDUCTASE INHIBITOR; AMIDE; GLYCOSIDE; N (3, 4, 5 TRI O BENZYLGALLOYL) 2, 3, 4, 6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLAMINE; N (3, 4, 5 TRI O BENZYLPHENYLACETYL) 2, 3, 4, 6 TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLAMINE; N GALLOYL BETA DEXTRO GLUCOPYRANOSYLAMINE; N PHENYLACETYL BETA DEXTRO GLUCOPYRANOSYLAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLOADDITION; DIABETES MELLITUS; DIABETIC EYE DISEASE; DRUG DESIGN; DRUG POTENTIATION; DRUG STABILITY; DRUG SYNTHESIS; ENZYME INHIBITION; EYE DISEASE; HETERONUCLEAR MULTIPLE BOND CORRELATION; HUMAN; IN VITRO STUDY; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGAN CULTURE;

ALDEHYDE REDUCTASE; AMIDES; DRUG DESIGN; DRUG STABILITY; ENZYME INHIBITORS; GLYCOSIDES; HUMANS; HYDROLYZABLE TANNINS;

EID: 84892568699     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401311d     Document Type: Article

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