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Volumn 60, Issue 2, 2014, Pages 331-338

Role of Myc in hepatocellular proliferation and hepatocarcinogenesis

Author keywords

BrdU; Cell cycle control; Cell proliferation; Myc; Tumorigenesis

Indexed keywords

DIETHYLNITROSAMINE; FATTY ACID; MYC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; SERUM ALBUMIN; TAMOXIFEN;

EID: 84892553819     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.09.024     Document Type: Article
Times cited : (68)

References (41)
  • 1
    • 0021041054 scopus 로고
    • Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor
    • K. Kelly, B.H. Cochran, C.D. Stiles, and P. Leder Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor Cell 35 1983 603 610
    • (1983) Cell , vol.35 , pp. 603-610
    • Kelly, K.1    Cochran, B.H.2    Stiles, C.D.3    Leder, P.4
  • 2
  • 3
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis
    • P. Yaswen, M. Goyette, P.R. Shank, and N. Fausto Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis Mol cell Biol 5 1985 780 786
    • (1985) Mol Cell Biol , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3    Fausto, N.4
  • 4
    • 0033551389 scopus 로고    scopus 로고
    • Mysterious liaisons: The relationship between c-Myc and the cell cycle
    • A.J. Obaya, M.K. Mateyak, and J.M. Sedivy Mysterious liaisons: the relationship between c-Myc and the cell cycle Oncogene 18 1999 2934 2941
    • (1999) Oncogene , vol.18 , pp. 2934-2941
    • Obaya, A.J.1    Mateyak, M.K.2    Sedivy, J.M.3
  • 5
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
    • J.M. Peters, R.C. Cattley, and F.J. Gonzalez Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643 Carcinogenesis 18 1997 2029 2033
    • (1997) Carcinogenesis , vol.18 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 6
    • 34250163202 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
    • Y.M. Shah, K. Morimura, Q. Yang, T. Tanabe, M. Takagi, and F.J. Gonzalez Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation Mol Cell Biol 27 2007 4238 4247
    • (2007) Mol Cell Biol , vol.27 , pp. 4238-4247
    • Shah, Y.M.1    Morimura, K.2    Yang, Q.3    Tanabe, T.4    Takagi, M.5    Gonzalez, F.J.6
  • 7
    • 54349087788 scopus 로고    scopus 로고
    • Myc's broad reach
    • M. Eilers, and R.N. Eisenman Myc's broad reach Genes Dev 22 2008 2755 2766
    • (2008) Genes Dev , vol.22 , pp. 2755-2766
    • Eilers, M.1    Eisenman, R.N.2
  • 8
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with Myc
    • N. Meyer, and L.Z. Penn Reflecting on 25 years with Myc Nat Rev Cancer 8 2008 976 990
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 9
    • 70350728803 scopus 로고    scopus 로고
    • Myc-induced cancer cell energy metabolism and therapeutic opportunities
    • C.V. Dang, A. Le, and P. Gao Myc-induced cancer cell energy metabolism and therapeutic opportunities Clin Cancer Res 15 2009 6479 6483
    • (2009) Clin Cancer Res , vol.15 , pp. 6479-6483
    • Dang, C.V.1    Le, A.2    Gao, P.3
  • 10
    • 0027245446 scopus 로고
    • Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: Interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis
    • H. Murakami, N.D. Sanderson, P. Nagy, P.A. Marino, G. Merlino, and S.S. Thorgeirsson Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis Cancer Res 53 1993 1719 1723
    • (1993) Cancer Res , vol.53 , pp. 1719-1723
    • Murakami, H.1    Sanderson, N.D.2    Nagy, P.3    Marino, P.A.4    Merlino, G.5    Thorgeirsson, S.S.6
  • 11
    • 7744220635 scopus 로고    scopus 로고
    • Myc inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • C.M. Shachaf, A.M. Kopelman, C. Arvanitis, A. Karlsson, S. Beer, and S. Mandl et al. Myc inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer Nature 431 2004 1112 1117
    • (2004) Nature , vol.431 , pp. 1112-1117
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3    Karlsson, A.4    Beer, S.5    Mandl, S.6
  • 12
    • 79960006190 scopus 로고    scopus 로고
    • 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression
    • S. Hu, A. Balakrishnan, R.A. Bok, B. Anderton, P.E. Larson, and S.J. Nelson et al. 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression Cell Metab 14 2011 131 142
    • (2011) Cell Metab , vol.14 , pp. 131-142
    • Hu, S.1    Balakrishnan, A.2    Bok, R.A.3    Anderton, B.4    Larson, P.E.5    Nelson, S.J.6
  • 13
    • 4043062056 scopus 로고    scopus 로고
    • Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse
    • M. Schuler, A. Dierich, P. Chambon, and D. Metzger Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse Genesis 39 2004 167 172
    • (2004) Genesis , vol.39 , pp. 167-172
    • Schuler, M.1    Dierich, A.2    Chambon, P.3    Metzger, D.4
  • 15
    • 79960745146 scopus 로고    scopus 로고
    • Hypoxia-inducible transcription factor 2alpha promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis
    • A. Qu, M. Taylor, X. Xue, T. Matsubara, D. Metzger, and P. Chambon et al. Hypoxia-inducible transcription factor 2alpha promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis Hepatology 54 2011 472 483
    • (2011) Hepatology , vol.54 , pp. 472-483
    • Qu, A.1    Taylor, M.2    Xue, X.3    Matsubara, T.4    Metzger, D.5    Chambon, P.6
  • 16
    • 0020603511 scopus 로고
    • Kinetics of diethylnitrosamine hepatocarcinogenesis in the infant mouse
    • S.D. Vesselinovitch, and N. Mihailovich Kinetics of diethylnitrosamine hepatocarcinogenesis in the infant mouse Cancer Res 43 1983 4253 4259
    • (1983) Cancer Res , vol.43 , pp. 4253-4259
    • Vesselinovitch, S.D.1    Mihailovich, N.2
  • 17
    • 78549248181 scopus 로고    scopus 로고
    • PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells
    • A. Qu, Y.M. Shah, T. Matsubara, Q. Yang, and F.J. Gonzalez PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells Toxicol Sci 118 2010 404 410
    • (2010) Toxicol Sci , vol.118 , pp. 404-410
    • Qu, A.1    Shah, Y.M.2    Matsubara, T.3    Yang, Q.4    Gonzalez, F.J.5
  • 18
    • 40049088000 scopus 로고    scopus 로고
    • PPARalpha: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
    • F.J. Gonzalez, and Y.M. Shah PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators Toxicology 246 2008 2 8
    • (2008) Toxicology , vol.246 , pp. 2-8
    • Gonzalez, F.J.1    Shah, Y.M.2
  • 19
    • 37549008310 scopus 로고    scopus 로고
    • Widespread microRNA repression by Myc contributes to tumorigenesis
    • T.C. Chang, D. Yu, Y.S. Lee, E.A. Wentzel, D.E. Arking, and K.M. West et al. Widespread microRNA repression by Myc contributes to tumorigenesis Nat Genet 40 2008 43 50
    • (2008) Nat Genet , vol.40 , pp. 43-50
    • Chang, T.C.1    Yu, D.2    Lee, Y.S.3    Wentzel, E.A.4    Arking, D.E.5    West, K.M.6
  • 21
    • 0027315650 scopus 로고
    • A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice
    • A.C. Davis, M. Wims, G.D. Spotts, S.R. Hann, and A. Bradley A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice Genes Dev 7 1993 671 682
    • (1993) Genes Dev , vol.7 , pp. 671-682
    • Davis, A.C.1    Wims, M.2    Spotts, G.D.3    Hann, S.R.4    Bradley, A.5
  • 22
    • 84857740814 scopus 로고    scopus 로고
    • Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion
    • J.A. Sanders, C. Schorl, A. Patel, J.M. Sedivy, and P.A. Gruppuso Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion BMC Physiol 12 2012 1
    • (2012) BMC Physiol , vol.12 , pp. 1
    • Sanders, J.A.1    Schorl, C.2    Patel, A.3    Sedivy, J.M.4    Gruppuso, P.A.5
  • 23
    • 18844450701 scopus 로고    scopus 로고
    • C-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver
    • E. Baena, A. Gandarillas, M. Vallespinos, J. Zanet, O. Bachs, and C. Redondo et al. C-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver Proc Natl Acad Sci U S A 102 2005 7286 7291
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7286-7291
    • Baena, E.1    Gandarillas, A.2    Vallespinos, M.3    Zanet, J.4    Bachs, O.5    Redondo, C.6
  • 24
    • 0032898369 scopus 로고    scopus 로고
    • Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase
    • C. Postic, M. Shiota, K.D. Niswender, T.L. Jetton, Y. Chen, and J.M. Moates et al. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase J Biol Chem 274 1999 305 315
    • (1999) J Biol Chem , vol.274 , pp. 305-315
    • Postic, C.1    Shiota, M.2    Niswender, K.D.3    Jetton, T.L.4    Chen, Y.5    Moates, J.M.6
  • 25
    • 0033594893 scopus 로고    scopus 로고
    • Normal growth and development in the absence of hepatic insulin-like growth factor i
    • S. Yakar, J.L. Liu, B. Stannard, A. Butler, D. Accili, and B. Sauer et al. Normal growth and development in the absence of hepatic insulin-like growth factor I Proc Natl Acad Sci U S A 96 1999 7324 7329
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7324-7329
    • Yakar, S.1    Liu, J.L.2    Stannard, B.3    Butler, A.4    Accili, D.5    Sauer, B.6
  • 26
    • 0014608102 scopus 로고
    • Drug treatment of hyperlipidemia
    • D. Berkowitz Drug treatment of hyperlipidemia Mod Treat 6 1969 1341 1351
    • (1969) Mod Treat , vol.6 , pp. 1341-1351
    • Berkowitz, D.1
  • 27
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • I. Issemann, and S. Green Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 347 1990 645 650
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 28
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonists
    • B. Staels, and J.C. Fruchart Therapeutic roles of peroxisome proliferator-activated receptor agonists Diabetes 54 2005 2460 2470
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staels, B.1    Fruchart, J.C.2
  • 29
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • S.S. Lee, T. Pineau, J. Drago, E.J. Lee, J.W. Owens, and D.L. Kroetz et al. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators Mol Cell Biol 15 1995 3012 3022
    • (1995) Mol Cell Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6
  • 30
    • 0020002341 scopus 로고
    • Hepatic and renal effects of peroxisome proliferators: Biological implications
    • J.K. Reddy, J.R. Warren, M.K. Reddy, and N.D. Lalwani Hepatic and renal effects of peroxisome proliferators: biological implications Ann N Y Acad Sci 386 1982 81 110
    • (1982) Ann N y Acad Sci , vol.386 , pp. 81-110
    • Reddy, J.K.1    Warren, J.R.2    Reddy, M.K.3    Lalwani, N.D.4
  • 31
    • 35448958146 scopus 로고    scopus 로고
    • Direct regulation of the minichromosome maintenance complex by MycN in neuroblastoma
    • A. Koppen, R. Ait-Aissa, J. Koster, P.G. van Sluis, I. Ora, and H.N. Caron et al. Direct regulation of the minichromosome maintenance complex by MycN in neuroblastoma Eur J Cancer 43 2007 2413 2422
    • (2007) Eur J Cancer , vol.43 , pp. 2413-2422
    • Koppen, A.1    Ait-Aissa, R.2    Koster, J.3    Van Sluis, P.G.4    Ora, I.5    Caron, H.N.6
  • 32
    • 0034704397 scopus 로고    scopus 로고
    • Cell cycle. License withheld-geminin blocks DNA replication
    • Z. Lygerou, and P. Nurse Cell cycle. License withheld-geminin blocks DNA replication Science 290 2000 2271 2273
    • (2000) Science , vol.290 , pp. 2271-2273
    • Lygerou, Z.1    Nurse, P.2
  • 33
    • 0034595448 scopus 로고    scopus 로고
    • Uninterrupted MCM2-7 function required for DNA replication fork progression
    • K. Labib, J.A. Tercero, and J.F. Diffley Uninterrupted MCM2-7 function required for DNA replication fork progression Science 288 2000 1643 1647
    • (2000) Science , vol.288 , pp. 1643-1647
    • Labib, K.1    Tercero, J.A.2    Diffley, J.F.3
  • 34
    • 45849094037 scopus 로고    scopus 로고
    • Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex
    • D.I. Lin, P. Aggarwal, and J.A. Diehl Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex Proc Natl Acad Sci U S A 105 2008 8079 8084
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 8079-8084
    • Lin, D.I.1    Aggarwal, P.2    Diehl, J.A.3
  • 35
    • 17644432403 scopus 로고    scopus 로고
    • Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
    • Q. Liu, S. Guntuku, X.S. Cui, S. Matsuoka, D. Cortez, and K. Tamai et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint Genes Dev 14 2000 1448 1459
    • (2000) Genes Dev , vol.14 , pp. 1448-1459
    • Liu, Q.1    Guntuku, S.2    Cui, X.S.3    Matsuoka, S.4    Cortez, D.5    Tamai, K.6
  • 37
    • 81955162971 scopus 로고    scopus 로고
    • RAD51 paralogs: Roles in DNA damage signalling, recombinational repair and tumorigenesis
    • N. Suwaki, K. Klare, and M. Tarsounas RAD51 paralogs: roles in DNA damage signalling, recombinational repair and tumorigenesis Semin Cell Dev Biol 22 2011 898 905
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 898-905
    • Suwaki, N.1    Klare, K.2    Tarsounas, M.3
  • 38
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Y. Hayashita, H. Osada, Y. Tatematsu, H. Yamada, K. Yanagisawa, and S. Tomida et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation Cancer Res 65 2005 9628 9632
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3    Yamada, H.4    Yanagisawa, K.5    Tomida, S.6
  • 40
    • 14744288294 scopus 로고    scopus 로고
    • The Myc trilogy: Lord of RNA polymerases
    • T. Oskarsson, and A. Trumpp The Myc trilogy: lord of RNA polymerases Nat Cell Biol 7 2005 215 217
    • (2005) Nat Cell Biol , vol.7 , pp. 215-217
    • Oskarsson, T.1    Trumpp, A.2
  • 41
    • 0037115756 scopus 로고    scopus 로고
    • Overexpression of c-myc in diabetic mice restores altered expression of the transcription factor genes that regulate liver metabolism
    • E. Riu, T. Ferre, A. Mas, A. Hidalgo, S. Franckhauser, and F. Bosch Overexpression of c-myc in diabetic mice restores altered expression of the transcription factor genes that regulate liver metabolism Biochem J 368 2002 931 937
    • (2002) Biochem J , vol.368 , pp. 931-937
    • Riu, E.1    Ferre, T.2    Mas, A.3    Hidalgo, A.4    Franckhauser, S.5    Bosch, F.6


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