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Volumn 33, Issue 1, 2014, Pages 156-163

Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice

Author keywords

Hyperglycemia; Hyperlipidemia; Insulin; PPAR; Type 2 diabetes; Wogonin

Indexed keywords

ADIPONECTIN; CHOLESTEROL; GLUCOSE; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; WOGONIN;

EID: 84892552728     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2013.03.013     Document Type: Article
Times cited : (65)

References (34)
  • 1
    • 79953812623 scopus 로고    scopus 로고
    • Genetic predisposition to obesity leads to increased risk of type 2 diabetes
    • Li S., Zhao J.H., Luan J., Langenberg C., Luben R.N., Khaw K.T., et al. Genetic predisposition to obesity leads to increased risk of type 2 diabetes. Diabetologia 2011, 54:776-782.
    • (2011) Diabetologia , vol.54 , pp. 776-782
    • Li, S.1    Zhao, J.H.2    Luan, J.3    Langenberg, C.4    Luben, R.N.5    Khaw, K.T.6
  • 3
    • 0035130102 scopus 로고    scopus 로고
    • Diseases of liporegulation: new perspective on obesity and related disorders
    • Unger R.H., Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 2001, 15:312-321.
    • (2001) FASEB J , vol.15 , pp. 312-321
    • Unger, R.H.1    Orci, L.2
  • 4
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven G.M. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995, 75:473-486.
    • (1995) Physiol Rev , vol.75 , pp. 473-486
    • Reaven, G.M.1
  • 5
    • 47349107995 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor (PPAR) modulators and metabolic disorders
    • Cho M.C., Lee K., Paik S.G., Yoon D.Y. Peroxisome proliferators-activated receptor (PPAR) modulators and metabolic disorders. PPAR Res 2008, 2008:679137.
    • (2008) PPAR Res , vol.2008 , pp. 679137
    • Cho, M.C.1    Lee, K.2    Paik, S.G.3    Yoon, D.Y.4
  • 6
    • 77955057772 scopus 로고    scopus 로고
    • PPARalpha: an emerging therapeutic target in diabetic microvascular damage
    • Hiukka A., Maranghi M., Matikainen N., Taskinen M.R. PPARalpha: an emerging therapeutic target in diabetic microvascular damage. Nat Rev Endocrinol 2010, 6:454-463.
    • (2010) Nat Rev Endocrinol , vol.6 , pp. 454-463
    • Hiukka, A.1    Maranghi, M.2    Matikainen, N.3    Taskinen, M.R.4
  • 8
    • 33644645013 scopus 로고    scopus 로고
    • PPAR delta: a dagger in the heart of the metabolic syndrome
    • Barish G.D., Narkar V.A., Evans R.M. PPAR delta: a dagger in the heart of the metabolic syndrome. JClin Invest 2006, 116:590-597.
    • (2006) JClin Invest , vol.116 , pp. 590-597
    • Barish, G.D.1    Narkar, V.A.2    Evans, R.M.3
  • 9
    • 0031788318 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development
    • Braissant O., Wahli W. Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development. Endocrinology 1998, 139:2748-2754.
    • (1998) Endocrinology , vol.139 , pp. 2748-2754
    • Braissant, O.1    Wahli, W.2
  • 10
    • 0038353634 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis
    • Kim H., Haluzik M., Asghar Z., Yau D., Joseph J.W., Fernandez A.M., et al. Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis. Diabetes 2003, 52:1770-1778.
    • (2003) Diabetes , vol.52 , pp. 1770-1778
    • Kim, H.1    Haluzik, M.2    Asghar, Z.3    Yau, D.4    Joseph, J.W.5    Fernandez, A.M.6
  • 11
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P., Hu E., Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 1994, 79:1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 13
    • 0036250329 scopus 로고    scopus 로고
    • Differentiating members of the thiazolidinedione class: a focus on safety
    • Lebovitz H.E. Differentiating members of the thiazolidinedione class: a focus on safety. Diabetes Metab Res Rev 2002, 18(Suppl. 2):S23-S29.
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.SUPPL. 2
    • Lebovitz, H.E.1
  • 14
    • 84870685371 scopus 로고    scopus 로고
    • Thiazolidinedione use and cancer incidence in type 2 diabetes: a systematic review and meta-analysis
    • Colmers I.N., Bowker S.L., Johnson J.A. Thiazolidinedione use and cancer incidence in type 2 diabetes: a systematic review and meta-analysis. Diabetes Metab 2012, 38:475-484.
    • (2012) Diabetes Metab , vol.38 , pp. 475-484
    • Colmers, I.N.1    Bowker, S.L.2    Johnson, J.A.3
  • 15
    • 24644435394 scopus 로고    scopus 로고
    • Therapeutic potential of wogonin: a naturally occurring flavonoid
    • Tai M.C., Tsang S.Y., Chang L.Y., Xue H. Therapeutic potential of wogonin: a naturally occurring flavonoid. CNS Drug Rev 2005, 11:141-150.
    • (2005) CNS Drug Rev , vol.11 , pp. 141-150
    • Tai, M.C.1    Tsang, S.Y.2    Chang, L.Y.3    Xue, H.4
  • 16
    • 77954526792 scopus 로고    scopus 로고
    • Wogonin inhibits osteoclast formation induced by lipopolysaccharide
    • Jang S., Bak E.J., Kim M., Kim J.M., Chung W.Y., Cha J.H., et al. Wogonin inhibits osteoclast formation induced by lipopolysaccharide. Phytother Res 2010, 24:964-968.
    • (2010) Phytother Res , vol.24 , pp. 964-968
    • Jang, S.1    Bak, E.J.2    Kim, M.3    Kim, J.M.4    Chung, W.Y.5    Cha, J.H.6
  • 17
    • 70349241726 scopus 로고    scopus 로고
    • Aggravation by prostaglandin E2 of interleukin-6-dependent insulin resistance in hepatocytes
    • Henkel J., Neuschafer-Rube F., Pathe-Neuschafer-Rube A., Puschel G.P. Aggravation by prostaglandin E2 of interleukin-6-dependent insulin resistance in hepatocytes. Hepatology 2009, 50:781-790.
    • (2009) Hepatology , vol.50 , pp. 781-790
    • Henkel, J.1    Neuschafer-Rube, F.2    Pathe-Neuschafer-Rube, A.3    Puschel, G.P.4
  • 19
    • 67449135860 scopus 로고    scopus 로고
    • Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs
    • Peng J., Qi Q., You Q., Hu R., Liu W., Feng F., et al. Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. JEthnopharmacol 2009, 124:257-262.
    • (2009) JEthnopharmacol , vol.124 , pp. 257-262
    • Peng, J.1    Qi, Q.2    You, Q.3    Hu, R.4    Liu, W.5    Feng, F.6
  • 20
    • 0018869666 scopus 로고
    • Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes
    • Student A.K., Hsu R.Y., Lane M.D. Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. JBiol Chem 1980, 255:4745-4750.
    • (1980) JBiol Chem , vol.255 , pp. 4745-4750
    • Student, A.K.1    Hsu, R.Y.2    Lane, M.D.3
  • 21
    • 0032516081 scopus 로고    scopus 로고
    • ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand
    • Kim J.B., Wright H.M., Wright M., Spiegelman B.M. ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci U S A 1998, 95:4333-4337.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4333-4337
    • Kim, J.B.1    Wright, H.M.2    Wright, M.3    Spiegelman, B.M.4
  • 22
    • 77249168728 scopus 로고    scopus 로고
    • Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice
    • Takikawa M., Inoue S., Horio F., Tsuda T. Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice. JNutr 2010, 140:527-533.
    • (2010) JNutr , vol.140 , pp. 527-533
    • Takikawa, M.1    Inoue, S.2    Horio, F.3    Tsuda, T.4
  • 23
    • 80054067148 scopus 로고    scopus 로고
    • Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages
    • Chen C.Y., Shyue S.K., Ching L.C., Su K.H., Wu Y.L., Kou Y.R., et al. Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. JNutr Biochem 2011, 22:1015-1021.
    • (2011) JNutr Biochem , vol.22 , pp. 1015-1021
    • Chen, C.Y.1    Shyue, S.K.2    Ching, L.C.3    Su, K.H.4    Wu, Y.L.5    Kou, Y.R.6
  • 24
    • 84861992637 scopus 로고    scopus 로고
    • Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes
    • Ho F.M., Liao Y.H., Yang A.J., Lee Chao P.D., Hou Y.C., Huang C.T., et al. Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. JEthnopharmacol 2012, 142:175-187.
    • (2012) JEthnopharmacol , vol.142 , pp. 175-187
    • Ho, F.M.1    Liao, Y.H.2    Yang, A.J.3    Lee Chao, P.D.4    Hou, Y.C.5    Huang, C.T.6
  • 26
    • 2942529395 scopus 로고    scopus 로고
    • Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha
    • Kim S., Shin H.J., Kim S.Y., Kim J.H., Lee Y.S., Kim D.H., et al. Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha. Mol Cell Endocrinol 2004, 220:51-58.
    • (2004) Mol Cell Endocrinol , vol.220 , pp. 51-58
    • Kim, S.1    Shin, H.J.2    Kim, S.Y.3    Kim, J.H.4    Lee, Y.S.5    Kim, D.H.6
  • 27
    • 84862299874 scopus 로고    scopus 로고
    • Protection from metabolic dysregulation, obesity, and atherosclerosis by citrus flavonoids: activation of hepatic PGC1alpha-mediated fatty acid oxidation
    • 857142
    • Mulvihill E.E., Huff M.W. Protection from metabolic dysregulation, obesity, and atherosclerosis by citrus flavonoids: activation of hepatic PGC1alpha-mediated fatty acid oxidation. PPAR Res 2012, 2012. 857142.
    • (2012) PPAR Res , vol.2012
    • Mulvihill, E.E.1    Huff, M.W.2
  • 28
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001, 7:941-946.
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 29
    • 33644664433 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination
    • Tsuchida A., Yamauchi T., Takekawa S., Hada Y., Ito Y., Maki T., et al. Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination. Diabetes 2005, 54:3358-3370.
    • (2005) Diabetes , vol.54 , pp. 3358-3370
    • Tsuchida, A.1    Yamauchi, T.2    Takekawa, S.3    Hada, Y.4    Ito, Y.5    Maki, T.6
  • 30
    • 33847021451 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level
    • Hiuge A., Tenenbaum A., Maeda N., Benderly M., Kumada M., Fisman E.Z., et al. Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level. Arterioscler Thromb Vasc Biol 2007, 27:635-641.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 635-641
    • Hiuge, A.1    Tenenbaum, A.2    Maeda, N.3    Benderly, M.4    Kumada, M.5    Fisman, E.Z.6
  • 31
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
    • Lee Y.S., Kim W.S., Kim K.H., Yoon M.J., Cho H.J., Shen Y., et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006, 55:2256-2264.
    • (2006) Diabetes , vol.55 , pp. 2256-2264
    • Lee, Y.S.1    Kim, W.S.2    Kim, K.H.3    Yoon, M.J.4    Cho, H.J.5    Shen, Y.6
  • 33
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., et al. Role of AMP-activated protein kinase in mechanism of metformin action. JClin Invest 2001, 108:1167-1174.
    • (2001) JClin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4    Shen, X.5    Fenyk-Melody, J.6
  • 34
    • 23644445507 scopus 로고    scopus 로고
    • Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase
    • Huypens P., Quartier E., Pipeleers D., Van de Casteele M. Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase. Eur J Pharmacol 2005, 518:90-95.
    • (2005) Eur J Pharmacol , vol.518 , pp. 90-95
    • Huypens, P.1    Quartier, E.2    Pipeleers, D.3    Van de Casteele, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.