Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism

Aging Cell

Volumn 13, Issue 1, 2014, Pages 80-91

  Akasaki, Yuichi ^a,b   Ouchi, Noriyuki ^a,c   Izumiya, Yasuhiro ^d   Bernardo, Barbara L ^e   Lebrasseur, Nathan K ^f   Walsh, Kenneth ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

^e PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^f MAYO CLINIC   (United States)

Author keywords

Adipose tissue; Diabetes; Exercise; MTOR; Sarcopenia; Type IIb muscle

Indexed keywords

ADIPOSE TISSUE; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; FAST MUSCLE FIBER; FAT MASS; FATTY LIVER; GENE ACTIVATION; GLUCOSE METABOLISM; HYPERTROPHY; INSULIN RESISTANCE; INTERVENTION STUDY; LOW FAT DIET; METABOLIC DISORDER; METABOLIC PARAMETERS; MOUSE; MUSCLE CELL; MUSCLE GROWTH; MUSCLE HYPERTROPHY; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC MOUSE; ANIMAL; BODY WEIGHT; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; GLYCOLYSIS; METABOLISM; MUSCLE DEVELOPMENT; OBESITY; ORGAN SIZE; PATHOLOGY;

ANIMALIA; MUS MUSCULUS;

ANABOLIC AGENT; PROTEIN KINASE B; SIGNAL PEPTIDE;

ADIPOSITY; AGING; ANABOLIC AGENTS; ANIMALS; BODY COMPOSITION; BODY WEIGHT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLYCOLYSIS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, TRANSGENIC; MUSCLE DEVELOPMENT; MUSCLE FIBERS, FAST-TWITCH; ORGAN SIZE; PROTO-ONCOGENE PROTEINS C-AKT; TRANSGENES;

EID: 84892530909     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12153     Document Type: Article

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