Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase

Journal of Molecular Biology

Volumn 426, Issue 3, 2014, Pages 558-569

  Vaithiyalingam, Sivaraja ^a   Arnett, Diana R ^b   Aggarwal, Amit ^a   Eichman, Brandt F ^a,b   Fanning, Ellen ^b   Chazin, Walter J ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

DNA primase; DNA replication; manganese; X family DNA polymerase

Indexed keywords

DNA PRIMASE; NUCLEOTIDE; PROTEIN P48;

ARTICLE; BINDING AFFINITY; CALORIMETRY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME STRUCTURE; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; CELL DENSITY; CELL VIABILITY; DNA TEMPLATE; ENZYME ACTIVE SITE; HUMAN; IN VITRO STUDY; ISOTHERMAL TITRATION CALORIMETRY; NUCLEOTIDE BINDING SITE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

ARCHAEA; BACTERIA (MICROORGANISMS); EUKARYOTA;

AEP; ARCHAEO-EUKARYOTIC PRIMASE; DNA PRIMASE; DNA REPLICATION; ISOTHERMAL TITRATION CALORIMETRY; ITC; MANGANESE; ROOM TEMPERATURE; RT; SINGLE-STRANDED DNA; SSDNA; WILD TYPE; WT; X-FAMILY DNA POLYMERASE;

BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA PRIMASE; DNA PRIMERS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HUMANS; MANGANESE; PROTEIN CONFORMATION; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE;

EID: 84892496098     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.11.007     Document Type: Article

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