Systems biology in unruptured intracranial aneurysm: A metabolomics study in serum for the detection of biomarkers

Metabolomics

Volumn 10, Issue 1, 2014, Pages 52-62

  Ahmed, Shiek S S J ^a,b  

^a CHETTINAD HOSPITAL AND RESEARCH INSTITUTE   (India)

^b SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Aneurysm; Clustering; Gene expression; Metabolomics; Pathway analysis; Systems biology

Indexed keywords

ARGINASE; BIOLOGICAL MARKER; CARBAMOYL PHOSPHATE SYNTHASE; ORNITHINE CARBAMOYLTRANSFERASE;

ANALYSIS OF VARIANCE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; MALE; METABOLOMICS; MICROARRAY ANALYSIS; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; UNRUPTURED INTRACRANIAL ANEURYSM; UREA BLOOD LEVEL;

EID: 84892482024     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-013-0551-8     Document Type: Article

References (46)

1. Ahmed, S. S. J., & Ramakrishnan, V. (2012). Systems biological approach of molecular descriptors connectivity: Optimal descriptors for oral bioavailability prediction. PLoS ONE, 7(7), e40654.
2. Ahmed, S. S., Santosh, W., Kumar, S., & Christlet, H. T. (2009). Metabolic profiling of parkinson's disease: Evidence of biomarker from gene expression analysis and rapid neural network detection. Journal of Biomedical Science, 16, 63.
3. Alekseenko, A. V., Lemeshchenko, V. V., Pekun, T. G., Waseem, T. V., & Fedorovich, S. V. (2012). Glutamate-induced free radical formation in rat brain synaptosomes is not dependent on intrasynaptosomal mitochondria membrane potential. Neuroscience Letters, 513, 238-242.
4. Altaf-Ul-Amin, M., Shinbo, Y., Mihara, K., Kurokawa, K., & Kanaya, S. (2006). Development and implementation of an algorithm for detection of protein complexes in large interaction networks. BMC Bioinformatics, 14(7), 207.
5. Austin, G., Fisher, S., Dickson, D., Anderson, D., & Richardson, S. (1993). The significance of the extracellular matrix in intracranial aneurysms. Annals of Clinical and Laboratory Science, 23, 97-105.
6. Barrett, T., Wilhite, S., Ledoux, P., et al. (2013). NCBI GEO: Archive for functional genomics data sets-update. Nucleic Acids Research, 41, D991-D995.
7. Caranci, F., Briganti, F., Cirillo, L., Leonardi, M., and Muto, M. (2013) Epidemiology and genetics of intracranial aneurysms. Eur J Radiol. pii: S0720-048X(13)00011-9.
8. Chalouhi, N., Ali, M. S., Jabbour, P. M., et al. (2012a). Biology of intracranial aneurysms: Role of inflammation. Journal of Cerebral Blood Flow and Metabolism, 32, 1659-1676.
9. Chalouhi, N., Ali, M. S., Starke, R. M., et al. (2012b). Cigarette smoke and inflammation: Role in cerebral aneurysm formation and rupture. Mediators of Inflammation, 2012, 271582.
10. Crawley, F., Clifton, A., & Brown, M. M. (1999). Should we screen for familial intracranial aneurysm? Stroke, 30, 312-316.
11. Diana, R. W., Elizabeth, J., Joseph, P., et al. (2010). Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells. Journal of Biological Chemistry, 285, 30516-30522.
12. Donald, R. W., Di John, G., & Vincent, J. P. (1971). Manual and automated methods for urea nitrogen measurement in whole serum. Clinical Chemistry, 17, 891-895.
13. Douglas, C., & Isabel, L. (1997). Gelatinase activity and the occurrence of cerebral aneurysms. Stroke, 28, 799-804.
14. Dunne, V. G., Bhattachayya, S., Besser, M., Rae, C., & Griffin, J. L. (2005). Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: A pattern-recognition 1H NMR study. NMR in Biomedicine, 18, 24-33.
15. Fisher, M., & Zito, J. L. (1983). Focal cerebral ischemia distal to a cerebral aneurysm in hereditary hemorrhagic telangiectasia. Stroke, 14, 419-421.
16. Frolkis, A., Knox, C., Lim, E., et al. (2010). SMPDB: The small molecule pathway database. Nucleic Acids Research, 38, D480-D487.
17. Fukushima, A., Kusano, M., Redestig, H., Arita, M., and Saito K. (2011) Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach. BMC Syst Biol. 1;5: 1.
18. Glantz, L., Nates, J. L., Trembovler, V., Bass, R., & Shohami, E. (1996). Polyamines induce blood-brain barrier disruption and edema formation in the rat. Journal of Basic and Clinical Physiology and Pharmacology, 7, 1-10.
19. Helbok, R., Ko, S. B., Schmidt, J. M., et al. (2011). Global cerebral edema and brain metabolism after subarachnoid hemorrhage. Stroke, 42, 1534-1539.
20. Joanna, P., Michal, K., Tadeusz, K., et al. (2010). Gene expression profiles in human ruptured and unruptured intracranial aneurysms: What is the role of inflammation? Stroke, 41, 224-231.
21. Jung, J. Y., Lee, H. S., Kang, D. G., et al. (2011). 1H-NMR-based metabolomics study of cerebral infarction. Stroke, 42, 1282-1288.
22. Kett-White, R., Hutchinson, P. J., al-Rawi, P. G., et al. (2002). Extracellular lactate/pyruvate and glutamate changes in patients during per-operative episodes of cerebral ischaemia. Acta Neurochirurgica Supplementum, 81, 363-365.
23. Li, L., Yang, X., Jiang, F., Dusting, G. J., & Wu, Z. (2010). Transcriptome-wide characterization of gene expression associated with unruptured intracranial aneurysms. European Neurology, 62, 330-337.
24. Lotfi, H. B., & James, M. P. (2011). Current imaging assessment and treatment of intracranial aneurysms. American Journal of Roentgenol, 196, 132-144.
25. Lu, G., Huang, L., Zhang, X. L., et al. (2011). Geng influence of hemodynamic factors on rupture of intracranial aneurysms: Patient-specific 3D mirror aneurysms model computational fluid dynamics simulation. American Journal of Neuroradiology, 32, 1255-1261.
26. Marchese, E., Vignati, A., Albanese, A., et al. (2010). Comparative evaluation of genome-wide gene expression profiles in ruptured and unruptured human intracranial aneurysms. Journal of Biological Regulators and Homeostatic Agents, 24, 185-195.
27. Massieu, L., Gómez-Román, N., & Montiel, T. (2000). In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate. Experimental Neurology, 165, 257-267.
28. Mori, K., Nakajima, K., & Maeda, M. (1993). Long-term monitoring of CSF lactate levels and lactate/pyruvate ratios following subarachnoid haemorrhage. Acta Neurochir (Wien), 125, 20-26.
29. Muralikrishna, R., James, F. H., & Robert, J. D. (1999). Polyamine response to CNS injury: for better or for worse? Recent Research Developments in Neurochemistry, 2, 517-532.
30. Neil-Dwyer, G., Bartlett, J. R., Nicholls, A. C., Narcisi, P., & Pope, F. M. (1983). Collagen deficiency and ruptured cerebral aneurysms. A clinical and biochemical study. Journal of Neurosurgery, 59, 16-20.
31. Nilsson, O. G., Säveland, H., Boris-Möller, F., Brandt, L., & Wieloch, T. (1996). Increased levels of glutamate in patients with subarachnoid haemorrhage as measured by intracerebral microdialysis. Acta Neurochirurgica Supplementum, 67, 45-47.
32. Nishiumi, S., Kobayashi, T., Ikeda, A., et al. (2012). A novel serum metabolomics-based diagnostic approach for colorectal cancer. PLoS ONE, 7(7), e40459.
33. Ohsawa, N. (1990). Recent progress in polyamine research. Human Cell, 3, 91-98.
34. Parfenova, H., Basuroy, S., Bhattacharya, S., et al. (2006). Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: Contributions of HO-1 and HO-2 to cytoprotection. American Journal of Physiology Cell Physiology, 290, 1399-1410.
35. Parfenova, H., Carratu, P., Tcheranova, D., Fedinec, A., Pourcyrous, M., & Leffler, C. W. (2005). Epileptic seizures cause extended postictal cerebral vascular dysfunction that is prevented by HO-1 overexpression. American Journal of Physiology: Heart and Circulatory Physiology, 288, H2843-H2850.
36. Pentimalli, L., Modesti, A., Vignati, A., et al. (2004). Role of apoptosis in intracranial aneurysm rupture. Journal of Neurosurgery, 101, 1018-1025.
37. Pisapia, J. M., Wendell, L. C., Kumar, M. A., Zager, E. L., & Levine, J. M. (2011). Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage Neurocrit Care, 15, 134-138.
38. Psychogios, N., Hau, D. D., Peng, J., et al. (2011). The human serum metabolome. PLoS ONE, 6(2), e16957.
39. Reynolds, I. J., & Hastings, T. G. (1995). Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. Journal of Neuroscience, 5, 3318-3327.
40. Roder, C., Kasuya, H., Harati, A., Tatagiba, M., Inoue, I., & Krischek, B. (2012). Meta-analysis of microarray gene expression studies on intracranial aneurysms. Neuroscience, 201, 105-113.
41. Rupérez, F. J., Ramos-Mozo, P., Teul, J., Martinez-Pinna, R., Garcia, A., Malet-Martino, M., et al. (2012). Metabolomic study of plasma of patients with abdominal aortic aneurysm. Analytical and Bioanalytical Chemistry, 403, 1651-1660.
42. Säveland, H., Nilsson, O. G., Boris-Möller, F., Wieloch, T., & Brandt, L. (1996). Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage. Neurosurgery, 38, 12-19.
43. Shah, S. H., Sun, J. L., Stevens, R. D., et al. (2012). Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease. American Heart Journal, 163, 844-850.
44. Southerland, A. M., Meschia, J. F., & Worrall, B. B. (2013). Shared associations of nonatherosclerotic, large-vessel, cerebrovascular arteriopathies: considering intracranial aneurysms, cervical artery dissection, moyamoya disease and fibromuscular dysplasia. Current Opinion in Neurology, 26, 13-28.
45. Tulamo, R., Frösen, J., Laaksamo, E., Niemelä, M., Laakso, A., & Hernesniemi, J. (2011). Why does the cerebral artery aneurysm rupture? Duodecim, 127, 244-252.
46. Yao, H., Matsumoto, T., Hirano, M., et al. (1990). Striatal glutamic acid and gamma-aminobutyric acid in transient cerebral ischemia in spontaneously hypertensive rats. Japanese Heart Journal, 31, 385-392.