Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells

Journal of Biological Chemistry

Volumn 285, Issue 40, 2010, Pages 30516-30522

  Wetmore, Diana R ^a   Joseloff, Elizabeth ^a   Pilewski, Joseph ^b   Lee, Douglas P ^c   Lawton, Kay A ^c   Mitchell, Matthew W ^c   Milburn, Michael V ^c   Ryals, John A ^c   Guo, Lining ^c  

^a Cystic Fibrosis Foundation Therapeutics   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c METABOLON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CELLS; GLUCOSE; METABOLISM; NUCLEOTIDES;

BIOCHEMICAL PATHWAY; CELLULAR METABOLISM; CELLULAR REGULATION; CELLULAR RESPONSE; CF-EFFECTS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; ENVIRONMENTAL PRESSURES; EPITHELIAL CELL RESPONSE; GLUCOSE METABOLISM; HUMAN AIRWAY; METABOLOMIC ANALYSIS; METABOLOMICS; MODEL SYSTEM; OSMOTIC STRESS; PATHOLOGICAL PROCESS; PENTOSE PHOSPHATE PATHWAY; PURINE NUCLEOTIDES; STATISTICAL ANALYSIS;

CELL CULTURE;

BIOLOGICAL MARKER; GLUCOSE; PENTOSE PHOSPHATE; PURINE NUCLEOTIDE; SORBITOL; CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PURINE NUCLEOSIDE;

ARTICLE; CELL METABOLISM; CHEMICAL ANALYSIS; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYSTIC FIBROSIS; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLOMICS; OSMOTIC STRESS; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; REPRODUCIBILITY; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; CARBOHYDRATE METABOLISM; CLINICAL TRIAL; EPITHELIUM CELL; FEMALE; GENETICS; MALE; METABOLISM; MULTICENTER STUDY; MUTATION; OSMOTIC PRESSURE; PATHOLOGY; RESPIRATORY TRACT MUCOSA;

BIOLOGICAL MARKERS; CARBOHYDRATE METABOLISM; COHORT STUDIES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; FEMALE; HUMANS; MALE; METABOLOMICS; MUTATION; OSMOTIC PRESSURE; OXIDATIVE STRESS; PURINE NUCLEOSIDES; RESPIRATORY MUCOSA;

EID: 77957261641     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.140806     Document Type: Article

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