-
1
-
-
0032411599
-
Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress
-
Amundson SA, Myers TG, Fornace AJ (1998). Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress. Oncogene, 17, 3287-99.
-
(1998)
Oncogene
, vol.17
, pp. 3287-3299
-
-
Amundson, S.A.1
Myers, T.G.2
Fornace, A.J.3
-
2
-
-
80052491760
-
MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells
-
Bridges KA, Hirai H, Buser CA, et al (2011). MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Clin Cancer Res, 17, 5638-48.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5638-5648
-
-
Bridges, K.A.1
Hirai, H.2
Buser, C.A.3
-
3
-
-
38949147038
-
G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer
-
Bucher N, Britten CD (2008). G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer. Br J Cancer, 98, 523-8.
-
(2008)
Br J Cancer
, vol.98
, pp. 523-528
-
-
Bucher, N.1
Britten, C.D.2
-
4
-
-
0028958705
-
Growth factor modulation of p53-mediated growth arrest versus apoptosis
-
Canman CE, Gilmer TM, Coutts SB, et al (1995). Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev, 9, 600-11.
-
(1995)
Genes Dev
, vol.9
, pp. 600-611
-
-
Canman, C.E.1
Gilmer, T.M.2
Coutts, S.B.3
-
5
-
-
84863799519
-
Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo
-
Carrassa L, Chila R, Lupi M, et al (2012). Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo. Cell Cycle, 11, 2507-17.
-
(2012)
Cell Cycle
, vol.11
, pp. 2507-2517
-
-
Carrassa, L.1
Chila, R.2
Lupi, M.3
-
6
-
-
3042537050
-
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy
-
Castedo M, Perfettini JL, Roumier T, et al (2004). Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene, 23, 4362-70.
-
(2004)
Oncogene
, vol.23
, pp. 4362-4370
-
-
Castedo, M.1
Perfettini, J.L.2
Roumier, T.3
-
7
-
-
0025611503
-
Genetic mechanisms of tumor suppression by the human p53 gene
-
Chen PL, Chen YM, Bookstein R, et al (1990). Genetic mechanisms of tumor suppression by the human p53 gene. Science, 250, 1576-80.
-
(1990)
Science
, vol.250
, pp. 1576-1580
-
-
Chen, P.L.1
Chen, Y.M.2
Bookstein, R.3
-
8
-
-
0042698478
-
Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function
-
Dixon H, Norbury CJ (2002). Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function. Cell Cycle, 1, 362-8.
-
(2002)
Cell Cycle
, vol.1
, pp. 362-368
-
-
Dixon, H.1
Norbury, C.J.2
-
9
-
-
0141429017
-
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer
-
Foulkes WD, Stefansson IM, Chappuis PO, et al (2003). Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst, 95, 1482-5.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1482-1485
-
-
Foulkes, W.D.1
Stefansson, I.M.2
Chappuis, P.O.3
-
10
-
-
0642280785
-
VEGF expression and its reguration by p53 gene transfection in endometrial carcinoma cells
-
Fujisawa T, Watanabe J, Kamata Y, et al (2003). VEGF expression and its reguration by p53 gene transfection in endometrial carcinoma cells. Hum Cell, 16, 47-54.
-
(2003)
Hum Cell
, vol.16
, pp. 47-54
-
-
Fujisawa, T.1
Watanabe, J.2
Kamata, Y.3
-
11
-
-
0030898436
-
Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiationinduced activation during embryogenesis
-
Gottlieb E, Haffner R, King A, et al (1997). Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiationinduced activation during embryogenesis. EMBO J, 16, 1381-90.
-
(1997)
EMBO J
, vol.16
, pp. 1381-1390
-
-
Gottlieb, E.1
Haffner, R.2
King, A.3
-
12
-
-
0032127463
-
p53 facilitates pRb cleavage in IL- 3-deprived cells: novel pro-apoptotic activity of p53
-
Gottlieb E, Oren M (1998). p53 facilitates pRb cleavage in IL- 3-deprived cells: novel pro-apoptotic activity of p53. EMBO J, 17, 3587-96.
-
(1998)
EMBO J
, vol.17
, pp. 3587-3596
-
-
Gottlieb, E.1
Oren, M.2
-
13
-
-
17144402207
-
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
-
Hirakawa S, Kodama S, Kunstfeld R, et al (2005). VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med, 201, 1089-99.
-
(2005)
J Exp Med
, vol.201
, pp. 1089-1099
-
-
Hirakawa, S.1
Kodama, S.2
Kunstfeld, R.3
-
14
-
-
30544441820
-
The global breast cancer burden: variations in epidemiology and survival
-
Hortobagyi GN, de la Garza Salazar J, Pritchard K, et al (2005). The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer, 6, 391-401.
-
(2005)
Clin Breast Cancer
, vol.6
, pp. 391-401
-
-
Hortobagyi, G.N.1
de la Garza Salazar, J.2
Pritchard, K.3
-
15
-
-
0025883159
-
Wee1(+)-like gene in human cells
-
Igarashi M, Nagata A, Jinno S, et al (1991). Wee1(+)-like gene in human cells. Nature, 353, 80-3.
-
(1991)
Nature
, vol.353
, pp. 80-83
-
-
Igarashi, M.1
Nagata, A.2
Jinno, S.3
-
16
-
-
65249161106
-
Integrated functional, gene expression and genomic analysis for the identification of cancer targets
-
Iorns E, Lord CJ, Grigoriadis A, et al (2009). Integrated functional, gene expression and genomic analysis for the identification of cancer targets. PLoS One, 4, 5120.
-
(2009)
PLoS One
, vol.4
, pp. 5120
-
-
Iorns, E.1
Lord, C.J.2
Grigoriadis, A.3
-
17
-
-
0037380598
-
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
-
Jiang M, Milner J (2003). Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells. Genes Dev, 17, 832-7.
-
(2003)
Genes Dev
, vol.17
, pp. 832-837
-
-
Jiang, M.1
Milner, J.2
-
18
-
-
80051761743
-
The role of Bcl-2 and its prosurvival relatives in tumourigenesis and cancer therapy
-
Kelly PN, Strasser A (2011). The role of Bcl-2 and its prosurvival relatives in tumourigenesis and cancer therapy. Cell Death Differ, 18, 1414-24.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
Strasser, A.2
-
19
-
-
33745115304
-
p53 and breast cancer, an update
-
Lacroix M, Toillon RA, Leclercq G (2006). p53 and breast cancer, an update. Endocr Relat Cancer, 13, 293-325.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 293-325
-
-
Lacroix, M.1
Toillon, R.A.2
Leclercq, G.3
-
20
-
-
0035903157
-
Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization
-
Lai Z, Ferry KV, Diamond MA, et al (2001). Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization. J Biol Chem, 276, 31357-67.
-
(2001)
J Biol Chem
, vol.276
, pp. 31357-31367
-
-
Lai, Z.1
Ferry, K.V.2
Diamond, M.A.3
-
21
-
-
33947587213
-
A new platinum complex of triazine demonstrates G1 arrest with novel biological profile in human breast cancer cell line, MDAMB- 468
-
Mandal S, Berube G, Asselin E, et al (2007). A new platinum complex of triazine demonstrates G1 arrest with novel biological profile in human breast cancer cell line, MDAMB- 468. Bioorg Med Chem Lett, 17, 2139-45.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2139-2145
-
-
Mandal, S.1
Berube, G.2
Asselin, E.3
-
22
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
Mir SE, De Witt Hamer PC, Krawczyk PM, et al (2010). In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell, 18, 244-57.
-
(2010)
Cancer Cell
, vol.18
, pp. 244-257
-
-
Mir, S.E.1
De Witt Hamer, P.C.2
Krawczyk, P.M.3
-
23
-
-
0028865988
-
Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression
-
Mukhopadhyay D, Tsiokas L, Sukhatme VP (1995). Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res, 55, 6161-5.
-
(1995)
Cancer Res
, vol.55
, pp. 6161-6165
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Sukhatme, V.P.3
-
24
-
-
77955655940
-
Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome
-
Murrow LM, Garimella SV, Jones TL, et al (2010). Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome. Breast Cancer Res Treat 122, 347-57.
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 347-357
-
-
Murrow, L.M.1
Garimella, S.V.2
Jones, T.L.3
-
25
-
-
0035884402
-
Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma
-
Pal S, Datta K, Mukhopadhyay D (2001). Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma. Cancer Res, 61, 6952-7.
-
(2001)
Cancer Res
, vol.61
, pp. 6952-6957
-
-
Pal, S.1
Datta, K.2
Mukhopadhyay, D.3
-
26
-
-
33750584219
-
Apoptotic markers p53, Bcl-2 and Bax in primary lung cancer
-
Porebska I, Wyrodek E, Kosacka M, et al (2006). Apoptotic markers p53, Bcl-2 and Bax in primary lung cancer. In Vivo, 20, 599-604.
-
(2006)
In Vivo
, vol.20
, pp. 599-604
-
-
Porebska, I.1
Wyrodek, E.2
Kosacka, M.3
-
27
-
-
0030882353
-
EGF effects on p53 in MDA-468 human breast cancer cells: implications for G1 arrest
-
Prasad KA, Church JG (1997). EGF effects on p53 in MDA-468 human breast cancer cells: implications for G1 arrest. Cell Prolif, 30, 81-94.
-
(1997)
Cell Prolif
, vol.30
, pp. 81-94
-
-
Prasad, K.A.1
Church, J.G.2
-
28
-
-
57749105899
-
Molecular targeted therapies for breast cancer treatment
-
Schlotter CM, Vogt U, Allgayer H, et al (2008). Molecular targeted therapies for breast cancer treatment. Breast Cancer Res, 10, 211.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 211
-
-
Schlotter, C.M.1
Vogt, U.2
Allgayer, H.3
-
29
-
-
84858854342
-
RNAi screening of the kinome with cytarabine in leukemias
-
Tibes R, Bogenberger JM, Chaudhuri L, et al (2012). RNAi screening of the kinome with cytarabine in leukemias. Blood, 119, 2863-72.
-
(2012)
Blood
, vol.119
, pp. 2863-2872
-
-
Tibes, R.1
Bogenberger, J.M.2
Chaudhuri, L.3
-
30
-
-
26444575972
-
Is p53 haploinsufficient for tumor suppression? Implications for the p53+/- mouse model in carcinogenicity testing.
-
Venkatachalam S, Tyner SD, Pickering CR, et al (2001). Is p53 haploinsufficient for tumor suppression?. Implications for the p53+/- mouse model in carcinogenicity testing. Toxicol Pathol, 29, 147-54.
-
(2001)
Toxicol Pathol
, vol.29
, pp. 147-154
-
-
Venkatachalam, S.1
Tyner, S.D.2
Pickering, C.R.3
-
31
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden KH, Lu X (2002). Live or let die: the cell's response to p53. Nat Rev Cancer, 2, 594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
32
-
-
16544392882
-
Knockdown of Chk1, Wee1 and Myt1 by RNA interference abrogates G2 checkpoint and induces apoptosis
-
Wang Y, Decker SJ, Sebolt-Leopold J (2004). Knockdown of Chk1, Wee1 and Myt1 by RNA interference abrogates G2 checkpoint and induces apoptosis. Cancer Biol Ther, 3, 305-13.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 305-313
-
-
Wang, Y.1
Decker, S.J.2
Sebolt-Leopold, J.3
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