Intermedin modulates hypoxic pulmonary vascular remodeling by inhibiting pulmonary artery smooth muscle cell proliferation

Pulmonary Pharmacology and Therapeutics

Volumn 27, Issue 1, 2014, Pages 1-9

  Mao, Sun Zhong ^a   Fan, Xiao Fang ^a   Xue, Feng ^a   Chen, Ran ^a   Chen, Xuan Ying ^a   Yuan, Gong Sheng ^a   Hu, Liang Gang ^a   Liu, Shu Fang ^a,b   Gong, Yong Sheng ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Endoplasmic reticulum stress; Hypoxia; Intermedin; L Arginine NO pathway; Proliferation; Pulmonary arterial hypertension

Indexed keywords

INTERMEDIN;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOXIA; HYPOXIC PULMONARY VASCULAR REMODELING; LUNG BLOOD VESSEL; MALE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER;

ENDOPLASMIC RETICULUM STRESS; HYPOXIA; INTERMEDIN; L-ARGININE-NO PATHWAY; PROLIFERATION; PULMONARY ARTERIAL HYPERTENSION;

ADRENOMEDULLIN; ANIMALS; ANOXIA; APOPTOSIS; ARGININE; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MEMBRANE GLYCOPROTEINS; MUSCLE, SMOOTH, VASCULAR; NEUROPEPTIDES; NITRIC OXIDE; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84892446270     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2013.06.004     Document Type: Article

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