The Ubiquitin Receptor S5a/Rpn10 Links Centrosomal Proteasomes with Dendrite Development in the Mammalian Brain

Cell Reports

Volumn 4, Issue 1, 2013, Pages 19-30

  Puram, Sidharth V ^a   Kim, Albert H ^b,c   Park, Hye Yeon ^a,c   Anckar, Julius ^a   Bonni, Azad ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEASOME; REGULATOR PROTEIN; RPN10 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CELLULAR DISTRIBUTION; CENTROSOME; CEREBELLUM; CONTROLLED STUDY; DENDRITE; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; BRAIN; CENTROSOME; DENDRITES; INHIBITOR OF DIFFERENTIATION PROTEIN 1; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; RATS;

EUKARYOTA; MAMMALIA; RODENTIA;

EID: 84892433922     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.06.006     Document Type: Article

References (33)

1. Anand G., Yin X., Shahidi A.K., Grove L., Prochownik E.V. Novel regulation of the helix-loop-helix protein Id1 by S5a, a subunit of the 26S proteasome. J.Biol. Chem. 1997, 272:19140-19151.
2. Benezra R., Davis R.L., Lockshon D., Turner D.L., Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 1990, 61:49-59.
3. Besche H.C., Peth A., Goldberg A.L. Getting to first base in proteasome assembly. Cell 2009, 138:25-28.
4. Bingol B., Wang C.F., Arnott D., Cheng D., Peng J., Sheng M. Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines. Cell 2010, 140:567-578.
5. Bornens M. The centrosome in cells and organisms. Science 2012, 335:422-426.
6. Bornens M., Paintrand M., Berges J., Marty M.C., Karsenti E. Structural and chemical characterization of isolated centrosomes. Cell Motil. Cytoskeleton 1987, 8:238-249.
7. Dantuma N.P., Lindsten K., Glas R., Jellne M., Masucci M.G. Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells. Nat. Biotechnol. 2000, 18:538-543.
8. Deveraux Q., Ustrell V., Pickart C., Rechsteiner M. A 26S protease subunit that binds ubiquitin conjugates. J.Biol. Chem. 1994, 269:7059-7061.
9. Djakovic S.N., Schwarz L.A., DeMartino G.N., Patrick G.N. Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II. J. Biol. Chem. 2009, 284:26655-26665.
10. Fu H., Reis N., Lee Y., Glickman M.H., Vierstra R.D. Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome. EMBO J. 2001, 20:7096-7107.
11. Gaudillière B., Konishi Y., de la Iglesia N., Yao Gl., Bonni A. A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis. Neuron 2004, 41:229-241.
12. Gillingham A.K., Munro S. The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin. EMBO Rep. 2000, 1:524-529.
13. Griffiths G.M., Tsun A., Stinchcombe J.C. The immunological synapse: a focal point for endocytosis and exocytosis. J.Cell Biol. 2010, 189:399-406.
14. Hasskarl J., Mern D.S., Münger K. Interference of the dominant negative helix-loop-helix protein ID1 with the proteasomal subunit S5A causes centrosomal abnormalities. Oncogene 2008, 27:1657-1664.
15. Hatten M.E., Heintz N. Mechanisms of neural patterning and specification in the developing cerebellum. Annu. Rev. Neurosci. 1995, 18:385-408.
16. Hershko A., Ciechanover A. The ubiquitin system. Annu. Rev. Biochem. 1998, 67:425-479.
17. Johnson E.S., Bartel B., Seufert W., Varshavsky A. Ubiquitin as a degradation signal. EMBO J. 1992, 11:497-505.
18. Kanaji S., Iwahashi J., Kida Y., Sakaguchi M., Mihara K. Characterization of the signal that directs Tom20 to the mitochondrial outer membrane. J.Cell Biol. 2000, 151:277-288.
19. Kim A.H., Puram S.V., Bilimoria P.M., Ikeuchi Y., Keough S., Wong M., Rowitch D., Bonni A. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 2009, 136:322-336.
20. Konishi Y., Stegmüller J., Matsuda T., Bonni S., Bonni A. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 2004, 303:1026-1030.
21. Mabb A.M., Ehlers M.D. Ubiquitination in postsynaptic function and plasticity. Annu. Rev. Cell Dev. Biol. 2010, 26:179-210.
22. O'Connell B.C., Harper J.W. Ubiquitin proteasome system (UPS): what can chromatin do for you?. Curr. Opin. Cell Biol. 2007, 19:206-214.
23. Puram S.V., Kim A.H., Ikeuchi Y., Wilson-Grady J.T., Merdes A., Gygi S.P., Bonni A. A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat. Neurosci. 2011, 14:973-983.
24. Puram S.V., Riccio A., Koirala S., Ikeuchi Y., Kim A.H., Corfas G., Bonni A. A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes Dev. 2011, 25:2659-2673.
25. Riedinger C., Boehringer J., Trempe J.F., Lowe E.D., Brown N.R., Gehring K., Noble M.E., Gordon C., Endicott J.A. Structure of Rpn10 and its interactions with polyubiquitin chains and the proteasome subunit Rpn12. J.Biol. Chem. 2010, 285:33992-34003.
26. Rosenzweig R., Bronner V., Zhang D., Fushman D., Glickman M.H. Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. J.Biol. Chem. 2012, 287:14659-14671.
27. Stauffer T.P., Ahn S., Meyer T. Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr. Biol. 1998, 8:343-346.
28. Takeuchi J., Fujimuro M., Yokosawa H., Tanaka K., Toh-e A. Rpn9 is required for efficient assembly of the yeast 26S proteasome. Mol. Cell. Biol. 1999, 19:6575-6584.
29. van Nocker S., Sadis S., Rubin D.M., Glickman M., Fu H., Coux O., Wefes I., Finley D., Vierstra R.D. The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover. Mol. Cell. Biol. 1996, 16:6020-6028.
30. Varshavsky A. The N-end rule: functions, mysteries, uses. Proc. Natl. Acad. Sci. USA 1996, 93:12142-12149.
31. Verma R., Oania R., Graumann J., Deshaies R.J. Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system. Cell 2004, 118:99-110.
32. Yamada T., Yang Y., Bonni A. Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity. Trends Neurosci. 2013, 36:218-226.
33. Young P., Deveraux Q., Beal R.E., Pickart C.M., Rechsteiner M. Characterization of two polyubiquitin binding sites in the 26S protease subunit 5a. J.Biol. Chem. 1998, 273:5461-5467.