Inhibition of the CXCL12/CXCR4-axis as preventive therapy for radiation-induced pulmonary fibrosis

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Shu, Hui Kuo G ^a   Yoon, Younghyoun ^a   Hong, Samuel ^a   Xu, Kaiming ^a   Gao, Huiying ^a   Hao, Chunhai ^a   Torres Gonzalez, Edilson ^b   Nayra, Cardenes ^b   Rojas, Mauricio ^b   Shim, Hyunsuk ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; MESSENGER RNA; MSX 122; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; HETEROCYCLIC COMPOUND; N,N'-(1,4-PHENYLENEBIS(METHYLENE))DIPYRIMIDIN-2-AMINE; PYRIMIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; LUNG FIBROSIS; LUNG FLUID; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; RADIATION INDUCED PULMONARY FIBROSIS; RADIATION INJURY; TRANSGENIC MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPLICATION; COMPUTER ASSISTED TOMOGRAPHY; DISEASE MODEL; GENETICS; LUNG; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PULMONARY FIBROSIS; RADIATION RESPONSE; RADIOGRAPHY;

ANIMALS; CHEMOKINE CXCL12; DISEASE MODELS, ANIMAL; FEMALE; HETEROCYCLIC COMPOUNDS; LUNG; MESENCHYMAL STROMAL CELLS; MICE; PULMONARY FIBROSIS; PYRIMIDINES; RADIATION INJURIES; RADIATION INJURIES, EXPERIMENTAL; RECEPTORS, CXCR4; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84892420931     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079768     Document Type: Article

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