Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Fertig, Elana J ^a   Markovic, Ana ^b   Danilova, Ludmila V ^a   Gaykalova, Daria A ^c   Cope, Leslie ^a   Chung, Christine H ^a   Ochs, Michael F ^a,d   Califano, Joseph A ^a,c,e  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e GREATER BALTIMORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA INTEGRATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC IDENTIFICATION; GENETIC LINKAGE; GLI1 GENE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS NEGATIVE HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN TISSUE; MALE; META PATHWAY ANALYSIS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; WART VIRUS;

CARCINOMA, SQUAMOUS CELL; CLUSTER ANALYSIS; DNA METHYLATION; DNA, NEOPLASM; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HEDGEHOG PROTEINS; HUMANS; MALE; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84892405276     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078127     Document Type: Article

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