메뉴 건너뛰기




Volumn 8, Issue 12, 2013, Pages

SPIN90 knockdown attenuates the formation and movement of endosomal vesicles in the early stages of epidermal growth factor receptor endocytosis

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYCLIN D1; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN SPIN90; RAB PROTEIN; UNCLASSIFIED DRUG;

EID: 84892377085     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082610     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 22944455544 scopus 로고    scopus 로고
    • Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration
    • Jekely G, Sung HH, Luque CM, Rorth P (2005) Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration. Dev Cell 9: 197-207.
    • (2005) Dev Cell , vol.9 , pp. 197-207
    • Jekely, G.1    Sung, H.H.2    Luque, C.M.3    Rorth, P.4
  • 2
    • 0013952103 scopus 로고
    • Studies on human leukocyte motility. I. Effects of alterations in pH, electrolyte concentration, and phagocytosis on leukocyte migration, adhesiveness, and aggregation
    • Bryant RE, DesPrez RM, VanWay MH, Rogers DE (1966) Studies on human leukocyte motility. I. Effects of alterations in pH, electrolyte concentration, and phagocytosis on leukocyte migration, adhesiveness, and aggregation. J Exp Med 124: 483-499.
    • (1966) J Exp Med , vol.124 , pp. 483-499
    • Bryant, R.E.1    DesPrez, R.M.2    VanWay, M.H.3    Rogers, D.E.4
  • 3
    • 0021365860 scopus 로고
    • Selective killing of Fc-receptor-bearing tumor cells through endocytosis of a drug-carrying immune complex
    • Shen WC, Ryser HJ (1984) Selective killing of Fc-receptor-bearing tumor cells through endocytosis of a drug-carrying immune complex. Proc Natl Acad Sci U S A 81: 1445-1447.
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 1445-1447
    • Shen, W.C.1    Ryser, H.J.2
  • 4
    • 0020060598 scopus 로고
    • Down-regulation of epidermal growth factor receptors in mouse embryos
    • Adamson ED, Warshaw JB (1982) Down-regulation of epidermal growth factor receptors in mouse embryos. Dev Biol 90: 430-434.
    • (1982) Dev Biol , vol.90 , pp. 430-434
    • Adamson, E.D.1    Warshaw, J.B.2
  • 5
    • 0021357886 scopus 로고
    • Down regulation of epidermal growth factor receptors: Direct demonstration of receptor degradation in human fibroblasts
    • Stoscheck CM, Carpenter G (1984) Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J Cell Biol 98: 1048-1053.
    • (1984) J Cell Biol , vol.98 , pp. 1048-1053
    • Stoscheck, C.M.1    Carpenter, G.2
  • 6
    • 78751704702 scopus 로고    scopus 로고
    • ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis
    • Schweitzer JK, Sedgwick AE, D'Souza-Schorey C (2011) ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis. Semin Cell Dev Biol 22: 39-47.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 39-47
    • Schweitzer, J.K.1    Sedgwick, A.E.2    D'Souza-Schorey, C.3
  • 7
    • 0013825447 scopus 로고
    • The stimulation of epidermal proliferation by a specific protein (EGF)
    • Cohen S (1965) The stimulation of epidermal proliferation by a specific protein (EGF). Dev Biol 12: 394-407.
    • (1965) Dev Biol , vol.12 , pp. 394-407
    • Cohen, S.1
  • 8
    • 0029074587 scopus 로고
    • Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
    • Miettinen PJ, Berger JE, Meneses J, Phung Y, Pedersen RA, et al. (1995) Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376: 337-341.
    • (1995) Nature , vol.376 , pp. 337-341
    • Miettinen, P.J.1    Berger, J.E.2    Meneses, J.3    Phung, Y.4    Pedersen, R.A.5
  • 9
    • 0029064203 scopus 로고
    • Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
    • Threadgill DW, Dlugosz AA, Hansen LA, Tennenbaum T, Lichti U, et al. (1995) Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269: 230-234.
    • (1995) Science , vol.269 , pp. 230-234
    • Threadgill, D.W.1    Dlugosz, A.A.2    Hansen, L.A.3    Tennenbaum, T.4    Lichti, U.5
  • 11
    • 0037429692 scopus 로고    scopus 로고
    • Trafficking of the ErbB receptors and its influence on signaling
    • Wiley HS (2003) Trafficking of the ErbB receptors and its influence on signaling. Exp Cell Res 284: 78-88.
    • (2003) Exp Cell Res , vol.284 , pp. 78-88
    • Wiley, H.S.1
  • 12
    • 1342323632 scopus 로고    scopus 로고
    • ErbB receptors: Directing key signaling networks throughout life
    • Holbro T, Hynes NE (2004) ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 44: 195-217.
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 14
    • 1642417606 scopus 로고    scopus 로고
    • APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment
    • Miaczynska M, Christoforidis S, Giner A, Shevchenko A, Uttenweiler-Joseph S, et al. (2004) APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell 116: 445-456.
    • (2004) Cell , vol.116 , pp. 445-456
    • Miaczynska, M.1    Christoforidis, S.2    Giner, A.3    Shevchenko, A.4    Uttenweiler-Joseph, S.5
  • 15
    • 0036787904 scopus 로고    scopus 로고
    • Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
    • Wang Y, Pennock S, Chen X, Wang Z (2002) Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol Cell Biol 22: 7279-7290.
    • (2002) Mol Cell Biol , vol.22 , pp. 7279-7290
    • Wang, Y.1    Pennock, S.2    Chen, X.3    Wang, Z.4
  • 16
    • 0042130366 scopus 로고    scopus 로고
    • Stimulation of cell proliferation by endosomal epidermal growth factor receptor as revealed through two distinct phases of signaling
    • Pennock S, Wang Z (2003) Stimulation of cell proliferation by endosomal epidermal growth factor receptor as revealed through two distinct phases of signaling. Mol Cell Biol 23: 5803-5815.
    • (2003) Mol Cell Biol , vol.23 , pp. 5803-5815
    • Pennock, S.1    Wang, Z.2
  • 17
    • 0035413603 scopus 로고    scopus 로고
    • Growth factor-dependent signaling and cell cycle progression
    • Jones SM, Kazlauskas A (2001) Growth factor-dependent signaling and cell cycle progression. Chem Rev 101: 2413-2423.
    • (2001) Chem Rev , vol.101 , pp. 2413-2423
    • Jones, S.M.1    Kazlauskas, A.2
  • 18
    • 0032541671 scopus 로고    scopus 로고
    • Cell cycle targets of Ras/Raf signalling
    • Kerkhoff E, Rapp UR (1998) Cell cycle targets of Ras/Raf signalling. Oncogene 17: 1457-1462.
    • (1998) Oncogene , vol.17 , pp. 1457-1462
    • Kerkhoff, E.1    Rapp, U.R.2
  • 19
    • 0035150990 scopus 로고    scopus 로고
    • Growth-factor-dependent mitogenesis requires two distinct phases of signalling
    • Jones SM, Kazlauskas A (2001) Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol 3: 165-172.
    • (2001) Nat Cell Biol , vol.3 , pp. 165-172
    • Jones, S.M.1    Kazlauskas, A.2
  • 20
    • 0041967156 scopus 로고    scopus 로고
    • Cell cycle regulation and neural differentiation
    • Galderisi U, Jori FP, Giordano A (2003) Cell cycle regulation and neural differentiation. Oncogene 22: 5208-5219.
    • (2003) Oncogene , vol.22 , pp. 5208-5219
    • Galderisi, U.1    Jori, F.P.2    Giordano, A.3
  • 21
    • 17044429330 scopus 로고    scopus 로고
    • A roller coaster ride with the mitotic cyclins
    • Fung TK, Poon RY (2005) A roller coaster ride with the mitotic cyclins. Semin Cell Dev Biol 16: 335-342.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 335-342
    • Fung, T.K.1    Poon, R.Y.2
  • 22
    • 0037449752 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo
    • Andl CD, Mizushima T, Nakagawa H, Oyama K, Harada H, et al. (2003) Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J Biol Chem 278: 1824-1830.
    • (2003) J Biol Chem , vol.278 , pp. 1824-1830
    • Andl, C.D.1    Mizushima, T.2    Nakagawa, H.3    Oyama, K.4    Harada, H.5
  • 23
    • 0033147449 scopus 로고    scopus 로고
    • SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation
    • Simpson F, Hussain NK, Qualmann B, Kelly RB, Kay BK, et al. (1999) SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation. Nat Cell Biol 1: 119-124.
    • (1999) Nat Cell Biol , vol.1 , pp. 119-124
    • Simpson, F.1    Hussain, N.K.2    Qualmann, B.3    Kelly, R.B.4    Kay, B.K.5
  • 24
    • 84861624344 scopus 로고    scopus 로고
    • Reconstitution of clathrin-coated bud and vesicle formation with minimal components
    • Dannhauser PN, Ungewickell EJ (2012) Reconstitution of clathrin-coated bud and vesicle formation with minimal components. Nat Cell Biol 14: 634-639.
    • (2012) Nat Cell Biol , vol.14 , pp. 634-639
    • Dannhauser, P.N.1    Ungewickell, E.J.2
  • 25
    • 80051785076 scopus 로고    scopus 로고
    • Control of growth cone motility and neurite outgrowth by SPIN90
    • Kim SM, Bae J, Cho IH, Choi KY, Park YJ, et al. (2011) Control of growth cone motility and neurite outgrowth by SPIN90. Exp Cell Res 317: 2276-2287.
    • (2011) Exp Cell Res , vol.317 , pp. 2276-2287
    • Kim, S.M.1    Bae, J.2    Cho, I.H.3    Choi, K.Y.4    Park, Y.J.5
  • 26
    • 55249121850 scopus 로고    scopus 로고
    • Immunogold Staining of London Resin (LR) White Sections for Transmission Electron Microscopy (TEM)
    • pdb prot5016
    • Skepper JN, Powell JM (2008) Immunogold Staining of London Resin (LR) White Sections for Transmission Electron Microscopy (TEM). CSH Protoc 2008: pdb prot5016.
    • (2008) CSH Protoc , vol.2008
    • Skepper, J.N.1    Powell, J.M.2
  • 27
    • 33748917630 scopus 로고    scopus 로고
    • Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts
    • Kim SH, Choi HJ, Lee KW, Hong NH, Sung BH, et al. (2006) Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts. Genes Cells 11: 1197-1211.
    • (2006) Genes Cells , vol.11 , pp. 1197-1211
    • Kim, S.H.1    Choi, H.J.2    Lee, K.W.3    Hong, N.H.4    Sung, B.H.5
  • 28
    • 0026744303 scopus 로고
    • The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
    • Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, et al. (1992) The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 70: 715-728.
    • (1992) Cell , vol.70 , pp. 715-728
    • Bucci, C.1    Parton, R.G.2    Mather, I.H.3    Stunnenberg, H.4    Simons, K.5
  • 29
    • 26844550881 scopus 로고    scopus 로고
    • Interaction of SPIN90 with dynamin I and its participation in synaptic vesicle endocytosis
    • Kim Y, Kim S, Lee S, Kim SH, Park ZY, et al. (2005) Interaction of SPIN90 with dynamin I and its participation in synaptic vesicle endocytosis. J Neurosci 25: 9515-9523.
    • (2005) J Neurosci , vol.25 , pp. 9515-9523
    • Kim, Y.1    Kim, S.2    Lee, S.3    Kim, S.H.4    Park, Z.Y.5
  • 30
    • 0034801952 scopus 로고    scopus 로고
    • Epidermal growth factor induces cyclin D1 in human pancreatic carcinoma: Evidence for a cyclin D1-dependent cell cycle progression
    • Poch B, Gansauge F, Schwarz A, Seufferlein T, Schnelldorfer T, et al. (2001) Epidermal growth factor induces cyclin D1 in human pancreatic carcinoma: evidence for a cyclin D1-dependent cell cycle progression. Pancreas 23: 280-287.
    • (2001) Pancreas , vol.23 , pp. 280-287
    • Poch, B.1    Gansauge, F.2    Schwarz, A.3    Seufferlein, T.4    Schnelldorfer, T.5
  • 31
    • 0034759543 scopus 로고    scopus 로고
    • Cyclin D1 antisense oligonucleotide inhibits cell growth stimulated by epidermal growth factor and induces apoptosis of gastric cancer cells
    • Saikawa Y, Kubota T, Otani Y, Kitajima M, Modlin IM (2001) Cyclin D1 antisense oligonucleotide inhibits cell growth stimulated by epidermal growth factor and induces apoptosis of gastric cancer cells. Jpn J Cancer Res 92: 1102-1109.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 1102-1109
    • Saikawa, Y.1    Kubota, T.2    Otani, Y.3    Kitajima, M.4    Modlin, I.M.5
  • 32
    • 79959364718 scopus 로고    scopus 로고
    • c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulation
    • Singh AK, Swarnalatha M, Kumar V (2011) c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulation. J Biol Chem 286: 21961-21970.
    • (2011) J Biol Chem , vol.286 , pp. 21961-21970
    • Singh, A.K.1    Swarnalatha, M.2    Kumar, V.3
  • 33
    • 33644828202 scopus 로고    scopus 로고
    • EGF stimulates proliferation of mouse embryonic stem cells: Involvement of Ca2+ influx and p44/42 MAPKs
    • Heo JS, Lee YJ, Han HJ (2006) EGF stimulates proliferation of mouse embryonic stem cells: involvement of Ca2+ influx and p44/42 MAPKs. Am J Physiol Cell Physiol 290: C123-133.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Heo, J.S.1    Lee, Y.J.2    Han, H.J.3
  • 34
    • 77949645984 scopus 로고    scopus 로고
    • Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor
    • Chapter 15: Unit 15 14
    • Sorkin A, Duex JE (2010) Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor. Curr Protoc Cell Biol Chapter 15: Unit 15 14.
    • (2010) Curr Protoc Cell Biol
    • Sorkin, A.1    Duex, J.E.2
  • 35
    • 0033981633 scopus 로고    scopus 로고
    • Rab GTPases coordinate endocytosis
    • Somsel Rodman J, Wandinger-Ness A (2000) Rab GTPases coordinate endocytosis. J Cell Sci 113 Pt 2: 183-192.
    • (2000) J Cell Sci , vol.113 , Issue.PART 2 , pp. 183-192
    • Somsel Rodman, J.1    Wandinger-Ness, A.2
  • 36
    • 67649470529 scopus 로고    scopus 로고
    • Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes
    • Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, et al. (2009) Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes. Nature 459: 1091-1097.
    • (2009) Nature , vol.459 , pp. 1091-1097
    • Ohya, T.1    Miaczynska, M.2    Coskun, U.3    Lommer, B.4    Runge, A.5
  • 37
    • 84871002075 scopus 로고    scopus 로고
    • Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking
    • Kim HJ, Zhong Q, Sheng ZH, Yoshimori T, Liang C, et al. (2012) Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking. J Cell Sci 125: 4740-4750.
    • (2012) J Cell Sci , vol.125 , pp. 4740-4750
    • Kim, H.J.1    Zhong, Q.2    Sheng, Z.H.3    Yoshimori, T.4    Liang, C.5
  • 38
    • 0037339887 scopus 로고    scopus 로고
    • Grb2 regulates internalization of EGF receptors through clathrin-coated pits
    • Jiang X, Huang F, Marusyk A, Sorkin A (2003) Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell 14: 858-870.
    • (2003) Mol Biol Cell , vol.14 , pp. 858-870
    • Jiang, X.1    Huang, F.2    Marusyk, A.3    Sorkin, A.4
  • 39
    • 84901236918 scopus 로고    scopus 로고
    • Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation
    • de Graauw M, Cao L, Winkel L, van Miltenburg MH, le Devedec SE, et al. (2013) Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation. Oncogene.
    • (2013) Oncogene
    • De Graauw, M.1    Cao, L.2    Winkel, L.3    Van Miltenburg, M.H.4    Le Devedec, S.E.5
  • 40
    • 0346752072 scopus 로고    scopus 로고
    • Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis
    • Galperin E, Sorkin A (2003) Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis. J Cell Sci 116: 4799-4810.
    • (2003) J Cell Sci , vol.116 , pp. 4799-4810
    • Galperin, E.1    Sorkin, A.2
  • 41
    • 68949156319 scopus 로고    scopus 로고
    • Cell migration is regulated by platelet-derived growth factor receptor endocytosis
    • Kawada K, Upadhyay G, Ferandon S, Janarthanan S, Hall M, et al. (2009) Cell migration is regulated by platelet-derived growth factor receptor endocytosis. Mol Cell Biol 29: 4508-4518.
    • (2009) Mol Cell Biol , vol.29 , pp. 4508-4518
    • Kawada, K.1    Upadhyay, G.2    Ferandon, S.3    Janarthanan, S.4    Hall, M.5
  • 42
    • 33750796999 scopus 로고    scopus 로고
    • Nuclear trafficking of secreted factors and cell-surface receptors: New pathways to regulate cell proliferation and differentiation, and involvement in cancers
    • Planque N (2006) Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers. Cell Commun Signal 4: 7.
    • (2006) Cell Commun Signal , vol.4 , pp. 7
    • Planque, N.1
  • 43
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy C, Wrana JL (2005) Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat Rev Mol Cell Biol 6: 112-126.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 44
    • 0027965262 scopus 로고
    • Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
    • Di Guglielmo GM, Baass PC, Ou WJ, Posner BI, Bergeron JJ (1994) Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J 13: 4269-4277.
    • (1994) EMBO J , vol.13 , pp. 4269-4277
    • Di Guglielmo, G.M.1    Baass, P.C.2    Ou, W.J.3    Posner, B.I.4    Bergeron, J.J.5
  • 45
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • Vieira AV, Lamaze C, Schmid SL (1996) Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274: 2086-2089.
    • (1996) Science , vol.274 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 46
    • 0035819073 scopus 로고    scopus 로고
    • NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
    • Howe CL, Valletta JS, Rusnak AS, Mobley WC (2001) NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron 32: 801-814.
    • (2001) Neuron , vol.32 , pp. 801-814
    • Howe, C.L.1    Valletta, J.S.2    Rusnak, A.S.3    Mobley, W.C.4
  • 47
    • 84860493602 scopus 로고    scopus 로고
    • RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans
    • Skorobogata O, Rocheleau CE (2012) RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans. PLoS One 7: e36489.
    • (2012) PLoS One , vol.7
    • Skorobogata, O.1    Rocheleau, C.E.2
  • 48
    • 33845775698 scopus 로고    scopus 로고
    • Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling
    • Kobayashi S, Shimamura T, Monti S, Steidl U, Hetherington CJ, et al. (2006) Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling. Cancer Res 66: 11389-11398.
    • (2006) Cancer Res , vol.66 , pp. 11389-11398
    • Kobayashi, S.1    Shimamura, T.2    Monti, S.3    Steidl, U.4    Hetherington, C.J.5
  • 49
    • 0032529165 scopus 로고    scopus 로고
    • Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
    • Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, et al. (1998) Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev 12: 2469-2474.
    • (1998) Genes Dev , vol.12 , pp. 2469-2474
    • Robles, A.I.1    Rodriguez-Puebla, M.L.2    Glick, A.B.3    Trempus, C.4    Hansen, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.