Beauvericin ameliorates experimental colitis by inhibiting activated T cells via downregulation of the PI3K/Akt signaling pathway

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Wu, Xue Feng ^a   Xu, Rui ^a   Ouyang, Zi Jun ^a   Qian, Cheng ^a   Shen, Yan ^a   Wu, Xu Dong ^a   Gu, Yan Hong ^b   Xu, Qiang ^a   Sun, Yang ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BEAUVERICIN; CASPASE 12; CASPASE 3; CASPASE 9; DEXAMETHASONE; GAMMA INTERFERON; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B; STAT1 PROTEIN; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; COLITIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROHN DISEASE; DIARRHEA; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; ENZYME INHIBITION; ENZYME REGULATION; EXPERIMENTAL COLITIS; FEMALE; GAMMA INTERFERON BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MORTALITY; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TREATMENT RESPONSE; TUMOR NECROSIS FACTOR ALPHA BLOOD LEVEL; WEIGHT REDUCTION;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; COLITIS; DEPSIPEPTIDES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892376678     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083013     Document Type: Article

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