Establishment of a green fluorescent protein tracing murine model focused on the functions of host components in necrosis repair and the niche of subcutaneously implanted glioma

Oncology Reports

Volumn 31, Issue 2, 2014, Pages 657-664

  Lu, Zhao Hui ^a   Lv, Ke ^b   Zhang, Jin Shi ^a   Dai, Chun Gang ^c   Liu, Bin ^c   Ma, Xiao Yu ^c   He, Lin Ming ^c   Jia, Jing Yun ^c   Chen, Yan Ming ^a   Dai, Xing Liang ^a   Wang, Ai Dong ^a   Dong, Jun ^a   Zhang, Quan Bin ^b   Lan, Qing ^a   Huang, Qiang ^a  

^a SOOCHOW UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

^c Neurosurgical Department   (China)

Author keywords

Cancer stem cell; Green fluorescent protein nude mice; Tumor microenvironment; Tumor necrosis and repair

Indexed keywords

CD11B ANTIGEN; CD68 ANTIGEN; GREEN FLUORESCENT PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; TUMOR NECROSIS FACTOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CARCINOGENICITY; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; GLIOMA; GLIOMA CELL; HISTOPATHOLOGY; HOST CELL; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; INTERSTITIUM; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE REPAIR; TUMOR BLEEDING; TUMOR MICROENVIRONMENT; TUMOR NECROSIS; TUMOR VASCULARIZATION; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD11B; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BRAIN NEOPLASMS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GLIOMA; GREEN FLUORESCENT PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KI-67 ANTIGEN; MICE; MICE, INBRED C57BL; MICE, NUDE; MICE, TRANSGENIC; NECROSIS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; TRANSPLANTATION, HETEROLOGOUS; TUMOR MICROENVIRONMENT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892375909     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2873     Document Type: Article

References (28)

1. de Almeida Sassi F, Brunetto AL, Schwartsmann G, Roesler R and Abujamra AL: Glioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of niche. J Oncol 2012: 537861, 2012. doi:10.1.1155/2012/537861.
2. He H, Li MU and Niu CS: The pathological characteristics of glioma stem cell niches. J Clin Neurosci 19: 121-127, 2012.
3. Tavazoie M, Van der Veken L, Silva-Vargas V, et al: A specialized vascular niche for adult neural stem cells. Cell Stem Cell 3: 279-288, 2008.
4. Najbauer J, Huszthy PC, Barish ME, et al: Cellular host responses in gliomas. PLoS One 7: e35150, 2012.
5. Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ and Van Meir EG: Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol 7: 134-153, 2005.
6. Fei XF, Zhang QB, Dong J, et al: Development of a clinically relevant orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma through surgical tumor tissue injection with trocar. J Exp Clin Cancer Res 29: 84, 2010.
7. Charles NA, Holland EC, Gilbertson R, Glass R and Kettenmann H: The brain tumor microenvironment. Glia 60: 1169-1180, 2011.
8. Hoffman RM: Green fluorescent protein imaging of tumor cells in mice. Lab Animal 31: 34-41, 2002.
9. Farin A, Suzuki SO, Weiker M, Goldman JE, Bruce JN and Canoll P: Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis. Glia 53: 799-808, 2006.
10. Wan Y, Fei XF, Wang ZM, et al: Expression of miRNA-125b in the new highly invasive glioma stem cell and progenitor cell line SU3. Chin J Cancer 31: 207-214, 2012.
11. Gillespie DL, Whang K, Ragel BT, Flynn JR, Kelly DA and Jensen RL: Silencing of hypoxia inducible factor-1α by RNA interference attenuates human glioma cell growth in vivo. Clin Cancer Res 13: 2441-2448, 2007.
12. Ryan HE, Poloni M, McNulty W, Elson D, Gassmann M, Arbeit JM and Johnson RS: Hypoxia-inducible factor-1α is a positive factor in solid tumor growth. Cancer Res 60: 4010-4015, 2000.
13. Bos R,Van der Groep P, Greijer AE, et al: Levels of hypoxia-inducible factor-1α independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer 97: 1573-1581, 2003.
14. Zhong H, Semenza GL, Simons JW and De Marzo AM: Up-regulation of hypoxia-inducible factor 1α is an early event in prostate carcinogenesis. Cancer Detect Prev 28: 88-93, 2004.
15. Birner P, Schindl M, Obermair A, Plank C, Breitenecker G and Oberhuber G: Overexpression of hypoxia-inducible factor 1 α is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 60: 4693-4696, 2000.
16. Urano N, Fujiwara Y, Doki Y, et al: Overexpression of hypoxia-inducible factor-1 alpha in gastric adenocarcinoma. Gastric Cancer 9: 44-49, 2006.
17. Clottes E: Hypoxia inducible factor 1: regulation,involvement in carcinogenesis and target for anticancer therapy. Bull Cancer 92: 119-127, 2005 (In French).
18. Xia Y, Choi HK and Lee K: Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors. Eur J Med Chem 49: 24-40, 2012.
19. Lyu MA and Rosenblum MG: The immunocytokine scFv23/TNF sensitizes HER-2/neu-overexpressing SKBR-3 cells to tumor necrosis factor (TNF) via up-regulation of TNF receptor-1. Mol Cancer Ther 4: 1205-1213, 2005.
20. Ebert LM, Meuter S and Moser B: Homing and function of human skin γδ T cells and NK cells: relevance for tumor surveillance. J Immunol 176: 4331-4336, 2006.
21. Warren MA, Shoemaker SF, Shealy DJ, Bshara W and Ip MM: Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice. Mol Cancer Ther 8: 2655-2663, 2009.
22. Yin Y, Chen X and Shu Y: Gene expression of the invasive phenotype of TNF-α-treated MCF-7 cells. Biomed Pharmacother 63: 421-428, 2009.
23. Bettinger I, Thanos S and Paulus W: Microglia promote glioma migration. Acta Neuropathol 103: 351-355, 2002.
24. Markovic DS, Glass R, Synowitz M, Rooijen Nv and Kettenmann H: Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J Neuropathol Exp Neurol 64: 754-762, 2005.
25. Wu A, Wei J, Kong LY, et al: Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 12: 1113-1125, 2010.
26. Straussman R, Morikawa T, Shee K, et al: Tumour microenvironment elicits innate resistance to RAF inhibitors through HGF secretion. Nature 487: 500-504, 2012.
27. Borovski T, Verhoeff JJC, ten Cate R, et al: Tumor microvascular supports proliferation and expansion of glioma-propagating cells. In J Cancer 125: 1222-1230, 2009.
28. Gazdzinski LM and Nieman BJ: Cellular imaging and texture analysis distinguish differences in cellular dynamics in mouse brain tumors. Magn Reson Med: May 9, 2013. doi: 10.1002/mrm.24790.