Biotic activity of Ca2+-modulating non-traditional antimicrobial and -viral agents

Frontiers in Microbiology

Volumn 4, Issue DEC, 2013, Pages

  Clark, Kevin B ^a  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Antiifective; Bacteria; Calcium channel blockers; Drug design and development; Pathogen toxins; Probiotic; Protozoa; Viruses

Indexed keywords

1,4 DIHYDROPYRIDINE; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; BENZODIAZEPINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; PHENYLALKYLAMINE;

ARTICLE; BIOTIC STRESS; DISEASE COURSE; DRUG RESPONSE; ENZYME ACTIVITY; GASTROINTESTINAL ABSORPTION; HUMAN; IMMUNOSURVEILLANCE; INFECTION; MOTOR PERFORMANCE; NONHUMAN; PHYLOGENY; SIGNAL TRANSDUCTION;

EID: 84892189218     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2013.00381     Document Type: Article

References (51)

1. Alam, U., Hyseni, C., Symula, R. E., Brelsfoard, C., Wu, Y., Kruglov, O., et al. (2012). Implications of microfauna-host interactions for trypanosome transmission dynamics in Glossina fuscipes in Uganda. Appl. Environ. Microbiol. 78, 4627-4637. doi: 10.1128/AEM.00806-12.
2. Ben-Jacob, E., Becker, I., Shapira, Y., and Levine, H. (2004). Bacterial linguistic communication and social intelligence. Trends. Microbiol. 12, 366-372. doi: 10.1016/j.tim.2004.06.006.
3. Boulkroun, S., Guenin-Macé, L., Thoulouze, M. I., Monot, M., Merckx, A., Langsley, G., et al. (2010). Mycolactone suppresses T cell rsponsiveness by altering both early signaling and posttranslational events. J. Immunol. 184, 1436-1444. doi: 10.4049/jimmunol.0902854.
4. Burleigh, B. A., and Andrews, N. W. (1995). A 120-kDa alkaline peptidase from Trypanosoma cruzi is involved in the generation of a novel Ca(2+)-signaling factor for mammalian cells. J. Biol. Chem. 270, 5172-5180. doi: 10.1074/jbc.270.10.5172.
5. Burleigh, B. A., Caler, E. V., Webster, P., and Andrews, N. W. (1997). A cytosolic serine endopeptidase from Trypanosoma cruzi is required for the generation of Ca2+ signaling in mammalian cells. J. Cell Biol. 136, 609-620. doi: 10.1083/jcb.136.3.609.
6. Casadesus, J., and D'Ari, R. (2002). Memory in bacteria and phage. Bioessays 24, 512-518. doi: 10.1002/bies.10102.
7. Caselli, E., Galvan, M., Cassai, E., Caruso, A., Sighinolfi, L., and Di Luca, D. (2005). Human herpesvirus 8 enhanvces immunodeficiency virus replication in acutely infected cells and indues reactivation in latently infected cells. Blood 106, 2790-2797. doi: 10.1182/blood-2005-04-1390.
8. Cassone, A., and Cauda, R. (2012). Candida and candidiasis in HIV-infected patients: where commensalism, opportunistic behavior and frank pathogenicity lose their borders. AIDS 26, 1457-1472. doi: 10.1097/QAD.0b013e3283536ba8.
9. 2+ signaling in the induction of apoptosis by hepatitis B virus X protein. J. Biol. Chem. 278, 31745-31755. doi: 10.1074/jbc.M304202200.
10. Clark, K. B. (2013a). Editorial: new therapeutic bearings for drug repositioning. Curr. Top. Med. Chem. 13, 2281-2282. doi: 10.2174/15680266113136660159.
11. Clark, K. B. (2013b). "The mating judgments of microbes," in Social Learning Theory: Phylogenetic Considerations across Animal, Plant, and Microbial Taxa, ed K. B. Clark (Hauppauge, NY: Nova Science Publishers Inc), 173-200.
12. Clark, K. B., and Eisenstein, E. M. (2013). Targeting host store-operated Ca2+ release to attenuate viral infections. Curr. Top. Med. Chem. 13, 1916-1932. doi: 10.2174/15680266113139990128.
13. Clark, K. B., Eisenstein, E. M., and Krahl, S. E. (2013). Calcium antagonists: a ready prescription for treating infectious diseases? Curr. Top. Med. Chem. 13, 2291-2305. doi: 10.2174/15680266113136660161.
14. Contreras, X., Bennasser, Y., Chazal, N., Moreau, M., Leclerc, C., Tkaczuk, J., et al. (2005). Human immunodeficiency virus type 1 Tat protein induces an intracellular calcium increase in human monocytes that requires DHP receptors: Involvement in TNF-alpha production. Virology 332, 316-328. doi: 10.1016/j.virol.2004.11.032.
15. Crespi, B. J. (2001). The evolution of social behavior in microorganisms. Trends Ecol. Evol. 16, 178-183. doi: 10.1016/S0169-5347(01)02115-2.
16. Cyert, M. S. (2003). Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Biochem. Biophys. Res. Commun. 311, 1143-1150. doi: 10.1016/S0006-291X(03)01552-3.
17. Diniello, G. B., Algranati, I. D., and Goldemberg, S. H. (1998). Streptomycin bacterial action is dependent on polyamine endogenous levels in E. coli. Cell Mol. Biol. 44, 521-526.
18. Dreyfus, L. A., Harville, B., Howard, D. E., Shaban, R., Beatty, D. M., and Morris, S. J. (1993). Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (STB). Proc. Natl. Acad. Sci. U. S. A. 90, 3202-3206. doi: 10.1073/pnas.90.8.3202.
19. Fernandes, M. C., Cortez, M., Flannery, A. R., Tam, C., Mortara, R. A., and Andrews, N. W. (2011). Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion. J. Exp. Med. 208, 909-921. doi: 10.1084/jem.20102518.
20. Gearhart, T. L., and Bouchard, M. J. (2010a). Replication of the hepatitis B virus requires a calcium-dependent HBx-induced G1 phase arrest of hepatocytes. Virology 407, 14-25. doi: 10.1016/j.virol.2010.07.042.
21. Gearhart, T. L., and Bouchard, M. J. (2010b). The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication. J. Virol. 84, 2675-2686. doi: 10.1128/JVI.02196-09.
22. Guo, H. G., Pati, S., Sadowska, M., Charurat, M., and Reitz, M. (2004). Tumorigenesis by human herpesvirus 8 vGPCR is accelerated by human immunodeficiency virus type 1 Tat. J. Virol. 78, 9336-9342. doi: 10.1128/JVI.78.17.9336-9342.2004.
23. Hellingwerf, K. J. (2005). Bacterial observations: a rudimentary form of intelligence? Trends Microbiol. 13, 152-158. doi: 10.1016/j.tim.2005.02.001.
24. Huang, L. M., Chao, M. F., Chen, M. Y., Shih, H. M., Chiang, Y. P., Chuang, C. Y., et al. (2001). Reciprocal regulatory interaction between human herpesvirus 8 and human immunodeficiency virus type 1. J. Biol. Chem. 276, 13427-13432. doi: 10.1074/jbc.M011314200.
25. Jover, E., Tawk, M. Y., Laventie, B. J., Poulain, B., and Prévost, G. (2013). Staphylococcal leukotoxins trigger free intracellular Ca(2+) rise in neurons, signaling trough acidic stores and activation of store-operated channels. Cell Microbiol. 15, 742-758. doi: 10.1111/cmi.12069.
26. Kozubowski, L., Lee, S. C., and Heitman, J. (2009). Signaling pathways in the pathogenesis of Cryptococcus. Cell Microbiol. 11, 370-380. doi: 10.1111/j.1462-5822.2008.01273.x.
27. 2+]i homeostasis and induce neurotoxicity in human embryonic neurons. Eur. J. Neurosci. 7, 2285-2293. doi: 10.1111/j.1460-9568.1995.tb00649.x.
28. Leitch, G. J., Scanlon, M., Shaw, A., and Visvesvara, G. S. (2001). Role of glygoprotein in the course and treatment of Encephalitozoon microsporidiosis. Antimicrob. Agents Chemother. 45, 73-78. doi: 10.1128/AAC.45.1.73-78.2001.
29. Li, Y. J., Wang, H. L., and Li, T. S. (2012). Hepatitis B virus/human imunodeficiency virus coinfection: interaction among human immunodeficiency virus infection, chronic hepatitis B virus infection, and host immunity. Chin. Med. J. 125, 2371-2377.
30. Lowry, J. E., Leonhardt, J. A., Yao, C., Belden, E. L., and Andrews, G. P. (2013). Infection of C57BL/6 mice by Trypanosoma musculi modulates host immune responses during Brucella abortus cocolonization. J. Wildl. Dis. doi: 10.7589/2013-03-008. [Epub ahead of print].
31. Mani, K., Sandgren, S., Lilja, J., Cheng, F., Svensson, K., Persson, L., and Belting, M. (2007). HIV-Tat protein transduction domain specifically attenuates growth of polyamine deprived tumor cells. Mol. Cancer Ther. 6, 782-788. doi: 10.1158/1535-7163.MCT-06-0370.
32. Marijuán, P. C., Navarro, J., and del Moral, R. (2010). On prokaryotic intelligence: strategies for sensing the environment. Biosystems 99, 94-103. doi: 10.1016/j.biosystems.2009.09.004.
33. Meirelles, M. N., and De Souza, W. (1983). Interaction of lysosomes with endocytic vacuoles in macrophages simultaneously infected with Trypanosoma cruzi and Toxoplasma gondii. J. Submicrosc. Cytol. 15, 889-896.
34. Moreno, S. N., and Docampo, R. (2003). Calcium regulation in protozoan parasites. Curr. Opin. Microbiol. 6, 359-364. doi: 10.1016/S1369-5274(03)00091-2.
35. Niide, O., Suzuki, Y., Yoshimaru, T., Inoue, T., Takayama, T., and Ra, C. (2006). Fungal metabolite gliotoxin blocks mast cell activation by a calcium-and superoxide-dependent mechanism: implications for immunosuppressive activities. Clin. Immunol. 118, 108-116. doi: 10.1016/j.clim.2005.08.012.
36. Pathak, S., Wentzel-Larsen, T., and Asjö, B. (2010). Effects of in vitro HIV-1 infection on mycobaterial growth in peripheral blood monocyte-derived macrophages. Infect. Immun. 78, 4022-4032. doi: 10.1128/IAI.00106-10.
37. Peacock, L., Ferris, V., Bailey, M., and Gibson, W. (2007). Dynamics of infection and competition between two strains of Trypanosoma brucei brucei in the tsetse fly observed using fluorescent markers. Kinetoplastid Biol. Dis. 6, 4. doi: 10.1186/1475-9292-6-4.
38. Prendergast, M. A., Rogers, D. T., Mulholland, P. J., Littelton, J. M., Wilkins, L. H. Jr., Self, R. L., et al. (2002). Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-meythl-D-aspartate receptor. Brain Res. 954, 300-307. doi: 10.1016/S0006-8993(02)03360-7.
39. 2+ mobilization and microfilament rearrangement in host cells. J. Cell Biol. 129, 1263-1273. doi: 10.1083/jcb.129.5.1263.
40. 2+-dependent cell signaling. J. Infect. Dis. 182, 240-251. doi: 10.1086/315676.
41. Romano, J. D., de Beaumont, C., Carrasco, J. A., Ehrenman, K., Bavoil, P. M., and Coppens, I. (2013). Fierce competition between Toxoplasma and Chlamydia for host cell structures in dually infected cells. Eukaryot. Cell 12, 265. doi: 10.1128/EC.00313-12.
42. 2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site. Brain Res. 995, 39-45. doi: 10.1016/j.brainres.2003.09.052.
43. Snyder, D. S., and Small, P. L. (2003). Uptake and cellular actions of mycolactone, a virulence determinant for Mycobacterium ulcerans. Microb. Pathog. 34, 91-101. doi: 10.1016/S0882-4010(02)00210-3.
44. 2+ transients. J. Exp. Med. 179, 1017-1022. doi: 10.1084/jem.179.3.1017.
45. Toossi, Z., Wu., M., Hirsch, C. S., Mayanja-Kizza, H., Baseke, J., Aung, H., et al. (2012). Activation of P-TEFb at sites of dual HIV/TB infection, and inhibition of MTB-induced HIV transcription activation by the inhibitor of CDK9, Indirubin-3'-monoxime. AIDS Res. Hum. Retroviruses 28, 182-187. doi: 10.1089/aid.2010.0211.
46. TranVan, N. G., Clair, C., Grompone, G., and Sansonetti, P. (2004). Calcium signalling during cell interactions with bacterial pathogens. Biol. Cell 96, 93-101. doi: 10.1016/j.biolcel.2003.10.006.
47. Ulrich, Y., and Schmid-Hempel, P. (2012). Host modulation of parasite competition in multiple infections. Proc. Biol. Sci. 279, 2982-2989. doi: 10.1098/rspb.2012.0474.
48. 2+/calmodulin-P13K hVPS34 cascade. J. Exp. Med. 198, 653-659. doi: 10.1084/jem.20030527.
49. Yang, B., and Bouchard, M. J. (2012). The hepatitis B virus X protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake. J. Virol. 86, 313-327. doi: 10.1128/JVI.06442-11.
50. 2+ and virus. Cell Calcium 46, 1-17. doi: 10.1016/j.ceca.2009.05.005.
51. Zocchi, M. R., Rubartelli, A., Morgavi, P., and Poggi, A. (1998). HIV-1 Tat inhibits human natural killer cell function by blocking L-type calcium channels. J. Immunol. 161, 2938-2943.