Proinflammatory cytokine induction of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in human adipocytes is mediated by MEK, C/EBPβ, and NF-κB/RelA

Journal of Clinical Endocrinology and Metabolism

Volumn 99, Issue 1, 2014, Pages

  Esteves, Cristina L ^a   Kelly, Val ^a   Breton, Amandine ^a,c   Taylor, Ashley I ^a   West, Christopher C ^a,b   Donadeu, Francesc X ^a,c   Péault, Bruno ^a,b   Seckl, Jonathan R ^a   Chapman, Karen E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; ACETYLSALICYLIC ACID; CCAAT ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; INFANT; MALE; METABOLIC SYNDROME X; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; SIMPSON GOLABI BEHMEL SYNDROME; UPREGULATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADIPOCYTES; ADULT; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELLS, CULTURED; CYTOKINES; ENZYME INDUCTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; INFANT; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; NF-KAPPA B; TRANSCRIPTION FACTOR RELA; YOUNG ADULT;

EID: 84892154015     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-1708     Document Type: Article

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