-
1
-
-
0024997614
-
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
-
Safe S (1990) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21: 51-88
-
(1990)
Crit Rev Toxicol
, vol.21
, pp. 51-88
-
-
Safe, S.1
-
2
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson O (1995) The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 35:307-340
-
(1995)
Annu Rev Pharmacol Toxicol
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
3
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison MS, Nagy SR (2003) Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43:309-334
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
5
-
-
71449114195
-
An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology
-
White SS, Birnbaum LS (2009) An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 27:197-211
-
(2009)
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev
, vol.27
, pp. 197-211
-
-
White, S.S.1
Birnbaum, L.S.2
-
6
-
-
84155196846
-
Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
-
Denison MS, Soshilov AA, He G, DeGroot DE, Zhao B (2011) Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol Sci 124:1-22
-
(2011)
Toxicol Sci
, vol.124
, pp. 1-22
-
-
Denison, M.S.1
Soshilov, A.A.2
He, G.3
DeGroot, D.E.4
Zhao, B.5
-
7
-
-
0001877503
-
Natural and synthetic ligands for the Ah receptor
-
In: Puga A, Wallace KB (eds Taylor & Francis, Philadelphia
-
Denison MS, Seidel SD, Rogers WJ, Ziccardi M, Winter GM, Heath-Pagliuso S (1999) Natural and synthetic ligands for the Ah receptor. In: Puga A, Wallace KB (eds) Molecular biology approaches to toxicology. Taylor & Francis, Philadelphia, pp 393-410
-
(1999)
Molecular biology approaches to toxicology
, pp. 393-410
-
-
Denison, M.S.1
Seidel, S.D.2
Rogers, W.J.3
Ziccardi, M.4
Winter, G.M.5
Heath-Pagliuso, S.6
-
9
-
-
34548363297
-
The aryl hydrocarbon receptor sans xenobiotics: Endogenous function in genetic model systems
-
McMillan BJ, Bradfi eld CA (2007) The aryl hydrocarbon receptor sans xenobiotics: Endogenous function in genetic model systems. Mol Pharmacol 72:487-498
-
(2007)
Mol Pharmacol
, vol.72
, pp. 487-498
-
-
McMillan, B.J.1
Bradfield, C.A.2
-
10
-
-
58849098054
-
Dioxins and cardiovascular disease mortality
-
Humblet O, Birnbaum L, Rimm E, Mittleman MA, Hauser R (2008) Dioxins and cardiovascular disease mortality. Environ Health Perspect 116:1443-1448
-
(2008)
Environ Health Perspect
, vol.116
, pp. 1443-1448
-
-
Humblet, O.1
Birnbaum, L.2
Rimm, E.3
Mittleman, M.A.4
Hauser, R.5
-
11
-
-
77958158354
-
Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance
-
Linden J, Lensu S, Tuomisto J, Pohjanvirta R (2010) Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance. Front Neuroendocrinol 31:452-478
-
(2010)
Front Neuroendocrinol
, vol.31
, pp. 452-478
-
-
Linden, J.1
Lensu, S.2
Tuomisto, J.3
Pohjanvirta, R.4
-
12
-
-
79952799854
-
Interactions of the aryl hydrocarbon receptor with infl ammatory mediators: Beyond CYP1A regulation
-
Vondracek J, Umannova L, Machala M (2011) Interactions of the aryl hydrocarbon receptor with infl ammatory mediators: Beyond CYP1A regulation. Curr Drug Metab 12:89-103
-
(2011)
Curr Drug Metab
, vol.12
, pp. 89-103
-
-
Vondracek, J.1
Umannova, L.2
Machala, M.3
-
13
-
-
84862303080
-
The aryl hydrocarbon receptor in infl ammatory bowel disease: Linking the environment to disease pathogenesis
-
Montelone I, MacDonald TT, Pallone F, Montelenoe G (2012) The aryl hydrocarbon receptor in infl ammatory bowel disease: Linking the environment to disease pathogenesis. Curr Opin Gastroenterol 28:310-313
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 310-313
-
-
Montelone, I.1
MacDonald, T.T.2
Pallone, F.3
Montelenoe, G.4
-
14
-
-
84879555576
-
The human Ah receptor: Hints from dioxin toxicities to deregulated target genes and physiological functions
-
Bock KW (2013) The human Ah receptor: Hints from dioxin toxicities to deregulated target genes and physiological functions. Biol Chem 394:729-739
-
(2013)
Biol Chem
, vol.394
, pp. 729-739
-
-
Bock, K.W.1
-
15
-
-
49449095646
-
Activation of the aryl hydrocarbon receptor is essential for mediating the anti-infl ammatory effects of a novel low molecular weight compound
-
Lawrence BP, Denison MS, Novak H, Vorderstrasse BA, Harrer N, Neruda W, Reichel C, Woisetschläger M (2008) Activation of the aryl hydrocarbon receptor is essential for mediating the anti-infl ammatory effects of a novel low molecular weight compound. Blood 112: 1158-1165
-
(2008)
Blood
, vol.112
, pp. 1158-1165
-
-
Lawrence, B.P.1
Denison, M.S.2
Novak, H.3
Vorderstrasse, B.A.4
Harrer, N.5
Neruda, W.6
Reichel, C.7
Woisetschläger, M.8
-
16
-
-
72749083607
-
The aryl hydrocarbon receptor as a target for estrogen receptornegative breast cancer chemotherapy
-
Zhang S, Lei P, Liu X, Walker K, Kotha L, Rowlands C, Safe S (2009) The aryl hydrocarbon receptor as a target for estrogen receptornegative breast cancer chemotherapy. Endocr Relat Cancer 16:835-844
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 835-844
-
-
Zhang, S.1
Lei, P.2
Liu, X.3
Walker, K.4
Kotha, L.5
Rowlands, C.6
Safe, S.7
-
17
-
-
84867619803
-
Aryl hydrocarbon receptor (AhR)-Active pharmaceuticals are selective AhR modulators in MDA-MB-468 and BT474 breast cancer cells
-
Jin U-H, Lee S-O, Safe S (2012) Aryl hydrocarbon receptor (AhR)-Active pharmaceuticals are selective AhR modulators in MDA-MB-468 and BT474 breast cancer cells. J Pharmacol Exp Ther 343:333-341
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 333-341
-
-
Jin, U.-H.1
Lee, S.-O.2
Safe, S.3
-
18
-
-
0035176468
-
Bioanalytical screening methods for dioxins and dioxin like compounds: A review of bioassay/biomarker technology
-
Behnisch PA, Hosoe K, Sakai S (2001) Bioanalytical screening methods for dioxins and dioxin like compounds: A review of bioassay/biomarker technology. Environ Int 27: 413-439
-
(2001)
Environ Int
, vol.27
, pp. 413-439
-
-
Behnisch, P.A.1
Hosoe, K.2
Sakai, S.3
-
19
-
-
0037156460
-
Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment
-
Hahn ME (2002) Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment. Sci Total Environ 289:49-69
-
(2002)
Sci Total Environ
, vol.289
, pp. 49-69
-
-
Hahn, M.E.1
-
20
-
-
3543036976
-
Recombinant cell related chemicals
-
Denison MS, Zhao B, Baston DS, Clark GC, Murata H, Han D-H (2004) Recombinant cell related chemicals. Talanta 63:1123-1133
-
(2004)
Talanta
, vol.63
, pp. 1123-1133
-
-
Denison, M.S.1
Zhao, B.2
Baston, D.S.3
Clark, G.C.4
Murata, H.5
Han, D.-H.6
-
21
-
-
2342489432
-
Comparison of recombinant cell bioassays for the detection of Ah receptor agonists
-
Han D-H, Nagy SR, Denison MS (2004) Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors 20:11-22
-
(2004)
Biofactors
, vol.20
, pp. 11-22
-
-
Han, D.-H.1
Nagy, S.R.2
Denison, M.S.3
-
22
-
-
0842269742
-
The H4IIE cell bioassay as an indicator of dioxinlike chemicals in wildlife and the environment
-
Whyte JJ, Schmitt CJ, Tillitt DE (2004) The H4IIE cell bioassay as an indicator of dioxinlike chemicals in wildlife and the environment. Crit Rev Toxicol 34:1-83
-
(2004)
Crit Rev Toxicol
, vol.34
, pp. 1-83
-
-
Whyte, J.J.1
Schmitt, C.J.2
Tillitt, D.E.3
-
23
-
-
26844566935
-
Speciesspecific recombinant cell lines as bioassay systems for the detection of 2, 3, 78-Tetrachlorodibenzo-p-dioxin-like chemicals
-
Garrison PM, Tullis K, Aarts JMMJG, Brouwer A, Giesy JP, Denison MS (1996) Speciesspecific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-like chemicals. Fundam Appl Toxicol 30:194-203
-
(1996)
Fundam Appl Toxicol
, vol.30
, pp. 194-203
-
-
Garrison, P.M.1
Tullis, K.2
Aarts, J.M.M.J.G.3
Brouwer, A.4
Giesy, J.P.5
Denison, M.S.6
-
24
-
-
0036158617
-
Development of a green fl uorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists
-
Nagy SR, Sanborn JR, Hammock BD, Denison MS (2002) Development of a green fl uorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists. Toxicol Sci 65:200-210
-
(2002)
Toxicol Sci
, vol.65
, pp. 200-210
-
-
Nagy, S.R.1
Sanborn, J.R.2
Hammock, B.D.3
Denison, M.S.4
-
25
-
-
80053450462
-
Third generation Ah receptor-responsive luciferase reporter plasmids: Amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness
-
He G, Tsutsumi T, Zhao B, Baston DS, Zhao J, Heath-Pagliuso S, Denison MS (2011) Third generation Ah receptor-responsive luciferase reporter plasmids: Amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicol Sci 123:511-522
-
(2011)
Toxicol Sci
, vol.123
, pp. 511-522
-
-
He, G.1
Tsutsumi, T.2
Zhao, B.3
Baston, D.S.4
Zhao, J.5
Heath-Pagliuso, S.6
Denison, M.S.7
-
26
-
-
0010636992
-
Analysis of the Ah receptor signal transduction pathway
-
In: Maines M, Costa LG, Reed DJ, Sassa S, Sipes IG (eds Wiley, New York
-
Denison MS, Rogers JM, Rushing SR, Jones CL, Tetangco SC, Heath-Pagliuso S (2002) Analysis of the Ah receptor signal transduction pathway. In: Maines M, Costa LG, Reed DJ, Sassa S, Sipes IG (eds) Current protocols in toxicology. Wiley, New York, pp 4.8.1-4.8.45
-
(2002)
Current protocols in toxicology.
, pp. 481-4845
-
-
Denison, M.S.1
Rogers, J.M.2
Rushing, S.R.3
Jones, C.L.4
Tetangco, S.C.5
Heath-Pagliuso, S.6
-
27
-
-
84891960109
-
Novel 2-Aminoisofl avones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cellspecific context
-
Wall RJ, He G, Denison MS, Congiu C, Onnis V, Fernandes A, Bell DR, Rose M, Rowlands JC, Balboni G (2012) Novel 2-Aminoisofl avones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cellspecific context. Toxicology 88:881-887
-
(2012)
Toxicology
, vol.88
, pp. 881-887
-
-
Wall, R.J.1
He, G.2
Denison, M.S.3
Congiu, C.4
Onnis, V.5
Fernandes, A.6
Bell, D.R.7
Rose, M.8
Rowlands, J.C.9
Balboni, G.10
-
28
-
-
77953329606
-
Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds
-
Zhao B, Baston DS, Khan E, Sorrentino C, Denison MS (2010) Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds. Sci China Chem 53:1010-1016
-
(2010)
Sci China Chem
, vol.53
, pp. 1010-1016
-
-
Zhao, B.1
Baston, D.S.2
Khan, E.3
Sorrentino, C.4
Denison, M.S.5
-
29
-
-
84874144884
-
Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor
-
Zhao B, Bohonowych JES, Timme-Laragy A, Jung D, Affatato AA, Rice RH, Di Giulio RT, Denison MS (2013) Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. PLoS One 8:e56860
-
(2013)
PLoS One
, vol.8
-
-
Zhao, B.1
Bohonowych, J.E.S.2
Timme-Laragy, A.3
Jung, D.4
Affatato, A.A.5
Rice, R.H.6
Di Giulio, R.T.7
Denison, M.S.8
-
30
-
-
0037144119
-
Ligand binding and activation of the Ah receptor
-
Denison MS, Pandini A, Nagy SR, Baldwin EP, Bonati L (2002) Ligand binding and activation of the Ah receptor. Chem Biol Interact 141: 3-24
-
(2002)
Chem Biol Interact
, vol.141
, pp. 3-24
-
-
Denison, M.S.1
Pandini, A.2
Nagy, S.R.3
Baldwin, E.P.4
Bonati, L.5
-
31
-
-
0031008407
-
Regulation of dioxin receptor function by omeprazole
-
Dzeletovic N, McGuire J, Daujat M, Tholander J, Ema M, Fujii-Kuriyama Y, Bergman J, Maurel P, Poellinger L (1997) Regulation of dioxin receptor function by omeprazole. J Biol Chem 272:12705-12713
-
(1997)
J Biol Chem
, vol.272
, pp. 12705-12713
-
-
Dzeletovic, N.1
McGuire, J.2
Daujat, M.3
Tholander, J.4
Ema, M.5
Fujii-Kuriyama, Y.6
Bergman, J.7
Maurel, P.8
Poellinger, L.9
-
32
-
-
3042629590
-
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins
-
Knockaert M, Blondel M, Bach S, Leost M, Elbi C, Hager GL, Nagy SR, Han D, Denison MS, French M, Ryan XP, Magiatis P, Polychronopoulos P, Greengard P, Skaltsounis L, Meijer L (2004) Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene 23:4400-4412
-
(2004)
Oncogene
, vol.23
, pp. 4400-4412
-
-
Knockaert, M.1
Blondel, M.2
Bach, S.3
Leost, M.4
Elbi, C.5
Hager, G.L.6
Nagy, S.R.7
Han, D.8
Denison, M.S.9
French, M.10
Ryan, X.P.11
Magiatis, P.12
Polychronopoulos, P.13
Greengard, P.14
Skaltsounis, L.15
Meijer, L.16
-
33
-
-
84867575767
-
An improved AhR reporter gene assay for analyzing dioxins in soil, sediment and fish
-
Chao HR, Wang YF, Wang YN, Lin DY, Gou YY, Chen CY, Chen KC, Wu WK, Chiang BA, Huang YT, Hsieh LT, Yeh KJ, Tsou TC (2012) An improved AhR reporter gene assay for analyzing dioxins in soil, sediment and fi sh. Bull Environ Contam Toxicol 89:739-743
-
(2012)
Bull Environ Contam Toxicol
, vol.89
, pp. 739-743
-
-
Chao, H.R.1
Wang, Y.F.2
Wang, Y.N.3
Lin, D.Y.4
Gou, Y.Y.5
Chen, C.Y.6
Chen, K.C.7
Wu, W.K.8
Chiang, B.A.9
Huang, Y.T.10
Hsieh, L.T.11
Yeh, K.J.12
Tsou, T.C.13
-
34
-
-
48749127971
-
Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays
-
Van der Linden SC, Heringa MB, Man HY, Sonneveld E, Puijker LM, Brouwer A, Van der Burg B (2008) Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays. Environ Sci Technol 42:5814-5820
-
(2008)
Environ Sci Technol
, vol.42
, pp. 5814-5820
-
-
Van Der Linden, S.C.1
Heringa, M.B.2
Man, H.Y.3
Sonneveld, E.4
Puijker, L.M.5
Brouwer, A.6
Van Der Burg, B.7
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