메뉴 건너뛰기




Volumn , Issue , 2014, Pages 221-235

Cell-based assays for identification of aryl hydrocarbon receptor (AhR) activators

Author keywords

Ah receptor; CAFLUX; CALUX; Green fluorescent protein; Luciferase; Quantitative real time PCR

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AROMATIC HYDROCARBON RECEPTOR ACTIVATOR; CYTOCHROME P450 1A1; ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84891942236     PISSN: 15572153     EISSN: 19406053     Source Type: Book Series    
DOI: 10.1007/978-1-62703-742-6_13     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0024997614 scopus 로고
    • Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
    • Safe S (1990) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21: 51-88
    • (1990) Crit Rev Toxicol , vol.21 , pp. 51-88
    • Safe, S.1
  • 2
    • 0028987872 scopus 로고
    • The aryl hydrocarbon receptor complex
    • Hankinson O (1995) The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 35:307-340
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 3
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison MS, Nagy SR (2003) Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43:309-334
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 5
    • 71449114195 scopus 로고    scopus 로고
    • An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology
    • White SS, Birnbaum LS (2009) An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 27:197-211
    • (2009) J Environ Sci Health C Environ Carcinog Ecotoxicol Rev , vol.27 , pp. 197-211
    • White, S.S.1    Birnbaum, L.S.2
  • 6
    • 84155196846 scopus 로고    scopus 로고
    • Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
    • Denison MS, Soshilov AA, He G, DeGroot DE, Zhao B (2011) Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol Sci 124:1-22
    • (2011) Toxicol Sci , vol.124 , pp. 1-22
    • Denison, M.S.1    Soshilov, A.A.2    He, G.3    DeGroot, D.E.4    Zhao, B.5
  • 8
    • 77955500692 scopus 로고    scopus 로고
    • Modulation of steroid hormone receptor activity
    • Stanisic V, Lonard DM, O'Malley BW (2010) Modulation of steroid hormone receptor activity. Prog Brain Res 181:153-176
    • (2010) Prog Brain Res , vol.181 , pp. 153-176
    • Stanisic, V.1    Lonard, D.M.2    O'Malley, B.W.3
  • 9
    • 34548363297 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor sans xenobiotics: Endogenous function in genetic model systems
    • McMillan BJ, Bradfi eld CA (2007) The aryl hydrocarbon receptor sans xenobiotics: Endogenous function in genetic model systems. Mol Pharmacol 72:487-498
    • (2007) Mol Pharmacol , vol.72 , pp. 487-498
    • McMillan, B.J.1    Bradfield, C.A.2
  • 11
    • 77958158354 scopus 로고    scopus 로고
    • Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance
    • Linden J, Lensu S, Tuomisto J, Pohjanvirta R (2010) Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance. Front Neuroendocrinol 31:452-478
    • (2010) Front Neuroendocrinol , vol.31 , pp. 452-478
    • Linden, J.1    Lensu, S.2    Tuomisto, J.3    Pohjanvirta, R.4
  • 12
    • 79952799854 scopus 로고    scopus 로고
    • Interactions of the aryl hydrocarbon receptor with infl ammatory mediators: Beyond CYP1A regulation
    • Vondracek J, Umannova L, Machala M (2011) Interactions of the aryl hydrocarbon receptor with infl ammatory mediators: Beyond CYP1A regulation. Curr Drug Metab 12:89-103
    • (2011) Curr Drug Metab , vol.12 , pp. 89-103
    • Vondracek, J.1    Umannova, L.2    Machala, M.3
  • 13
    • 84862303080 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor in infl ammatory bowel disease: Linking the environment to disease pathogenesis
    • Montelone I, MacDonald TT, Pallone F, Montelenoe G (2012) The aryl hydrocarbon receptor in infl ammatory bowel disease: Linking the environment to disease pathogenesis. Curr Opin Gastroenterol 28:310-313
    • (2012) Curr Opin Gastroenterol , vol.28 , pp. 310-313
    • Montelone, I.1    MacDonald, T.T.2    Pallone, F.3    Montelenoe, G.4
  • 14
    • 84879555576 scopus 로고    scopus 로고
    • The human Ah receptor: Hints from dioxin toxicities to deregulated target genes and physiological functions
    • Bock KW (2013) The human Ah receptor: Hints from dioxin toxicities to deregulated target genes and physiological functions. Biol Chem 394:729-739
    • (2013) Biol Chem , vol.394 , pp. 729-739
    • Bock, K.W.1
  • 15
    • 49449095646 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor is essential for mediating the anti-infl ammatory effects of a novel low molecular weight compound
    • Lawrence BP, Denison MS, Novak H, Vorderstrasse BA, Harrer N, Neruda W, Reichel C, Woisetschläger M (2008) Activation of the aryl hydrocarbon receptor is essential for mediating the anti-infl ammatory effects of a novel low molecular weight compound. Blood 112: 1158-1165
    • (2008) Blood , vol.112 , pp. 1158-1165
    • Lawrence, B.P.1    Denison, M.S.2    Novak, H.3    Vorderstrasse, B.A.4    Harrer, N.5    Neruda, W.6    Reichel, C.7    Woisetschläger, M.8
  • 16
    • 72749083607 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor as a target for estrogen receptornegative breast cancer chemotherapy
    • Zhang S, Lei P, Liu X, Walker K, Kotha L, Rowlands C, Safe S (2009) The aryl hydrocarbon receptor as a target for estrogen receptornegative breast cancer chemotherapy. Endocr Relat Cancer 16:835-844
    • (2009) Endocr Relat Cancer , vol.16 , pp. 835-844
    • Zhang, S.1    Lei, P.2    Liu, X.3    Walker, K.4    Kotha, L.5    Rowlands, C.6    Safe, S.7
  • 17
    • 84867619803 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AhR)-Active pharmaceuticals are selective AhR modulators in MDA-MB-468 and BT474 breast cancer cells
    • Jin U-H, Lee S-O, Safe S (2012) Aryl hydrocarbon receptor (AhR)-Active pharmaceuticals are selective AhR modulators in MDA-MB-468 and BT474 breast cancer cells. J Pharmacol Exp Ther 343:333-341
    • (2012) J Pharmacol Exp Ther , vol.343 , pp. 333-341
    • Jin, U.-H.1    Lee, S.-O.2    Safe, S.3
  • 18
    • 0035176468 scopus 로고    scopus 로고
    • Bioanalytical screening methods for dioxins and dioxin like compounds: A review of bioassay/biomarker technology
    • Behnisch PA, Hosoe K, Sakai S (2001) Bioanalytical screening methods for dioxins and dioxin like compounds: A review of bioassay/biomarker technology. Environ Int 27: 413-439
    • (2001) Environ Int , vol.27 , pp. 413-439
    • Behnisch, P.A.1    Hosoe, K.2    Sakai, S.3
  • 19
    • 0037156460 scopus 로고    scopus 로고
    • Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment
    • Hahn ME (2002) Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment. Sci Total Environ 289:49-69
    • (2002) Sci Total Environ , vol.289 , pp. 49-69
    • Hahn, M.E.1
  • 21
    • 2342489432 scopus 로고    scopus 로고
    • Comparison of recombinant cell bioassays for the detection of Ah receptor agonists
    • Han D-H, Nagy SR, Denison MS (2004) Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors 20:11-22
    • (2004) Biofactors , vol.20 , pp. 11-22
    • Han, D.-H.1    Nagy, S.R.2    Denison, M.S.3
  • 22
    • 0842269742 scopus 로고    scopus 로고
    • The H4IIE cell bioassay as an indicator of dioxinlike chemicals in wildlife and the environment
    • Whyte JJ, Schmitt CJ, Tillitt DE (2004) The H4IIE cell bioassay as an indicator of dioxinlike chemicals in wildlife and the environment. Crit Rev Toxicol 34:1-83
    • (2004) Crit Rev Toxicol , vol.34 , pp. 1-83
    • Whyte, J.J.1    Schmitt, C.J.2    Tillitt, D.E.3
  • 23
    • 26844566935 scopus 로고    scopus 로고
    • Speciesspecific recombinant cell lines as bioassay systems for the detection of 2, 3, 78-Tetrachlorodibenzo-p-dioxin-like chemicals
    • Garrison PM, Tullis K, Aarts JMMJG, Brouwer A, Giesy JP, Denison MS (1996) Speciesspecific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-like chemicals. Fundam Appl Toxicol 30:194-203
    • (1996) Fundam Appl Toxicol , vol.30 , pp. 194-203
    • Garrison, P.M.1    Tullis, K.2    Aarts, J.M.M.J.G.3    Brouwer, A.4    Giesy, J.P.5    Denison, M.S.6
  • 24
    • 0036158617 scopus 로고    scopus 로고
    • Development of a green fl uorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists
    • Nagy SR, Sanborn JR, Hammock BD, Denison MS (2002) Development of a green fl uorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists. Toxicol Sci 65:200-210
    • (2002) Toxicol Sci , vol.65 , pp. 200-210
    • Nagy, S.R.1    Sanborn, J.R.2    Hammock, B.D.3    Denison, M.S.4
  • 25
    • 80053450462 scopus 로고    scopus 로고
    • Third generation Ah receptor-responsive luciferase reporter plasmids: Amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness
    • He G, Tsutsumi T, Zhao B, Baston DS, Zhao J, Heath-Pagliuso S, Denison MS (2011) Third generation Ah receptor-responsive luciferase reporter plasmids: Amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicol Sci 123:511-522
    • (2011) Toxicol Sci , vol.123 , pp. 511-522
    • He, G.1    Tsutsumi, T.2    Zhao, B.3    Baston, D.S.4    Zhao, J.5    Heath-Pagliuso, S.6    Denison, M.S.7
  • 28
    • 77953329606 scopus 로고    scopus 로고
    • Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds
    • Zhao B, Baston DS, Khan E, Sorrentino C, Denison MS (2010) Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds. Sci China Chem 53:1010-1016
    • (2010) Sci China Chem , vol.53 , pp. 1010-1016
    • Zhao, B.1    Baston, D.S.2    Khan, E.3    Sorrentino, C.4    Denison, M.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.