메뉴 건너뛰기




Volumn 24, Issue 3, 2000, Pages 306-313

One-year treatment of obesity: A randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor

Author keywords

Cardiovascular risk factors; Gastrointestinal lipase inhibitor; Orlistat; Pharmacotherapy; Weight loss

Indexed keywords

ALPHA TOCOPHEROL; BETA CAROTENE; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL LIPASE; VITAMIN;

EID: 0034095342     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801128     Document Type: Article
Times cited : (253)

References (32)
  • 2
    • 0027437262 scopus 로고
    • Medical hazards of obesity
    • 2 Pi-Sunyer FX. Medical hazards of obesity. Ann Intern Med 1993; 119: 655-660.
    • (1993) Ann Intern Med , vol.119 , pp. 655-660
    • Pi-Sunyer, F.X.1
  • 6
    • 0029068682 scopus 로고
    • Obesity in Britain: Gluttony or sloth?
    • 6 Prentice AM, Jebb SA. Obesity in Britain: gluttony or sloth? Br Med J 1995; 7002: 437-439.
    • (1995) Br Med J , vol.7002 , pp. 437-439
    • Prentice, A.M.1    Jebb, S.A.2
  • 7
    • 0027443085 scopus 로고
    • Evidence for success of caloric restriction in weight loss and control. Summary of data from industry
    • 7 Hyman FN, Sempos E, Saltsman J, Glinsmann WH. Evidence for success of caloric restriction in weight loss and control. Summary of data from industry. Ann Intern Med 1993; 119: 681-687.
    • (1993) Ann Intern Med , vol.119 , pp. 681-687
    • Hyman, F.N.1    Sempos, E.2    Saltsman, J.3    Glinsmann, W.H.4
  • 8
    • 0028151299 scopus 로고
    • Long-term weight loss: The effect of pharmacologic agents
    • 8 Goldstein DJ, Parvin JH. Long-term weight loss: the effect of pharmacologic agents. Am J Clin Nutr 1994; 60: 647-657.
    • (1994) Am J Clin Nutr , vol.60 , pp. 647-657
    • Goldstein, D.J.1    Parvin, J.H.2
  • 11
    • 0030853477 scopus 로고    scopus 로고
    • Valvular heart disease associated with dexfenfluramine
    • 11 Cannistra LB, Davis SM, Bauman AG. Valvular heart disease associated with dexfenfluramine. New Engl J Med 1997; 337: 636.
    • (1997) New Engl J Med , vol.337 , pp. 636
    • Cannistra, L.B.1    Davis, S.M.2    Bauman, A.G.3
  • 12
    • 0003193759 scopus 로고    scopus 로고
    • Fenfluramine and dexfenfluramine withdrawn. Report from the Medicines Control Agency
    • 12 Fenfluramine and dexfenfluramine withdrawn. Report from the Medicines Control Agency. Curr Probl Pharmacovig 1997; 23: 13-14.
    • (1997) Curr Probl Pharmacovig , vol.23 , pp. 13-14
  • 13
    • 0026604775 scopus 로고
    • Initial studies in humans with the novel gastrointestinal lipase inhibitor Ro18-0647 (tetrahydrolipstatin)
    • 13 Hauptman JB, Jeunet FS, Hartmann D. Initial studies in humans with the novel gastrointestinal lipase inhibitor Ro18-0647 (tetrahydrolipstatin). Am J Clin Nutr 1992; 55: 309S-313S.
    • (1992) Am J Clin Nutr , vol.55
    • Hauptman, J.B.1    Jeunet, F.S.2    Hartmann, D.3
  • 14
    • 0028103894 scopus 로고
    • Retrospective population-based analysis of the dose - Response (fecal fat excretion) relationship of orlistat in normal and obese volunteers
    • 14 Zhi J, Melia AT, Guerciolini R, Chung J, Kinberg J, Hauptman JB, Patel IH. Retrospective population-based analysis of the dose - response (fecal fat excretion) relationship of orlistat in normal and obese volunteers. Clin Pharmacol Ther 1994; 56: 82-85.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 82-85
    • Zhi, J.1    Melia, A.T.2    Guerciolini, R.3    Chung, J.4    Kinberg, J.5    Hauptman, J.B.6    Patel, I.H.7
  • 17
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
    • 17 Sjöström L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HPF, Krempf M, for the European Multicentre Orlistat Study Group. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Lancet 1998; 352: 167-172.
    • (1998) Lancet , vol.352 , pp. 167-172
    • Sjöström, L.1    Rissanen, A.2    Andersen, T.3    Boldrin, M.4    Golay, A.5    Koppeschaar, H.P.F.6    Krempf, M.7
  • 21
    • 0021776312 scopus 로고
    • Predicting basal metabolic rate, new standards and review of previous work; human nutrition
    • 21 Schofield WN. Predicting basal metabolic rate, new standards and review of previous work; human nutrition. Clin Nutr 1985; 39C(Suppl 1): 5-41.
    • (1985) Clin Nutr , vol.39 C , Issue.SUPPL. 1 , pp. 5-41
    • Schofield, W.N.1
  • 22
    • 0030278351 scopus 로고    scopus 로고
    • Waist circumference as a screening tool for cardiovascular risk factors: Evaluation of Receiver Operating Characteristics (ROC)
    • 22 Han TS, van Leer EM, Seidell JC, Lean MEJ. Waist circumference as a screening tool for cardiovascular risk factors: evaluation of Receiver Operating Characteristics (ROC). Obes Res 1996; 4: 533-547.
    • (1996) Obes Res , vol.4 , pp. 533-547
    • Han, T.S.1    Van Leer, E.M.2    Seidell, J.C.3    Lean, M.E.J.4
  • 23
    • 0029015738 scopus 로고
    • Waist circumference as a measure for indicating need for weight management
    • 23 Lean MEJ, Han TS, Morrison CE. Waist circumference as a measure for indicating need for weight management. Br Med J 1995; 311: 158-161.
    • (1995) Br Med J , vol.311 , pp. 158-161
    • Lean, M.E.J.1    Han, T.S.2    Morrison, C.E.3
  • 25
    • 0028898298 scopus 로고
    • Dietary fat and obesity: Evidence from epidemiology
    • 25 Lissner L, Heitmann BL. Dietary fat and obesity: evidence from epidemiology. Eur J Clin Nutr 1995; 49: 79-90.
    • (1995) Eur J Clin Nutr , vol.49 , pp. 79-90
    • Lissner, L.1    Heitmann, B.L.2
  • 26
    • 0026753155 scopus 로고
    • Beneficial health effects of modest weight loss
    • 26 Goldstein DJ. Beneficial health effects of modest weight loss. Int J Obes 1992; 6: 397-415.
    • (1992) Int J Obes , vol.6 , pp. 397-415
    • Goldstein, D.J.1
  • 27
    • 0029067621 scopus 로고
    • Prospective study of intentional weight loss and mortality in never-smoking US white women aged 40-64 years
    • 27 Williamson DF, Pamuk E, Thun M, Flanders D, Byers T, Heath C. Prospective study of intentional weight loss and mortality in never-smoking US white women aged 40-64 years. Am J Epidemiol 1995; 141: 1128-1141.
    • (1995) Am J Epidemiol , vol.141 , pp. 1128-1141
    • Williamson, D.F.1    Pamuk, E.2    Thun, M.3    Flanders, D.4    Byers, T.5    Heath, C.6
  • 28
    • 0033559343 scopus 로고    scopus 로고
    • Prospective study of intentional weight loss and mortality in overweight white men aged 40-64 years
    • 28 Williamson DF, Pamuk E, Thun M, Flanders D, Byers T, Heath C. Prospective study of intentional weight loss and mortality in overweight white men aged 40-64 years. Am J Epidemiol 1999; 149: 491-503.
    • (1999) Am J Epidemiol , vol.149 , pp. 491-503
    • Williamson, D.F.1    Pamuk, E.2    Thun, M.3    Flanders, D.4    Byers, T.5    Heath, C.6
  • 30
    • 0025934778 scopus 로고
    • Gallstones: Pathogenesis
    • 30 Paumgartner G, Sauerbruch. Gallstones: pathogenesis. Lancet 1991; 338: 1117-1121.
    • (1991) Lancet , vol.338 , pp. 1117-1121
    • Paumgartner, G.1    Sauerbruch2
  • 31
    • 0029784311 scopus 로고    scopus 로고
    • The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers
    • 31 Melia AT, Koss-Twardy SG, Zhi J. The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers. J Clin Pharmac 1996; 36: 647-653.
    • (1996) J Clin Pharmac , vol.36 , pp. 647-653
    • Melia, A.T.1    Koss-Twardy, S.G.2    Zhi, J.3
  • 32
    • 0029989469 scopus 로고    scopus 로고
    • The effect of orlistat, an inhibitor of dietary fat absorption, on the pharmacokinetics of β-carotene in healthy volunteers
    • 32 Zhi J, Melia AT, Koss-Twardy SG, Arora S, Patel IH. The effect of orlistat, an inhibitor of dietary fat absorption, on the pharmacokinetics of β-carotene in healthy volunteers. J Clin Pharmac 1996; 36: 152-159.
    • (1996) J Clin Pharmac , vol.36 , pp. 152-159
    • Zhi, J.1    Melia, A.T.2    Koss-Twardy, S.G.3    Arora, S.4    Patel, I.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.