Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cells

Experimental Biology and Medicine

Volumn 239, Issue 1, 2014, Pages 105-115

  Pan, Qiuwei ^a   Fouraschen, Suomi M G ^a   de Ruiter, Petra E ^a   Dinjens, Winand N M ^a   Kwekkeboom, Jaap ^a   Tilanus, Hugo W ^a   van der Laan, Luc J W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

cell culture; genomic instability; MSCs; tumorigenic

Indexed keywords

EUROPIUM; MICRORNA; RNA;

ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL CULTURE; CELL GROWTH; CELL ISOLATION; CYTOLOGY; CYTOTOXICITY; DNA MICROARRAY; ENGRAFTMENT; FLOW CYTOMETRY; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENOMIC INSTABILITY; HIGH RESOLUTION GENOME WIDE DNA ANALYSIS; HUMAN; HUMAN CELL; MESENCHYMAL STROMA CELL; MOUSE; MTT ASSAY; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SHORT TANDEM REPEAT; STEM CELL EXPANSION; ANIMAL; BIOSYNTHESIS; CELL TRANSFORMATION; CHROMOSOME ABERRATION; CLINICAL TRIAL; FEMALE; GENE EXPRESSION REGULATION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE; TIME; XENOGRAFT;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHROMOSOME ABERRATIONS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MICRORNAS; RNA, NEOPLASM; TIME FACTORS;

EID: 84891919044     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213506802     Document Type: Article

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