Gemifloxacin inhibits migration and invasion and induces mesenchymal-epithelial transition in human breast adenocarcinoma cells

Journal of Molecular Medicine

Volumn 92, Issue 1, 2014, Pages 53-64

  Chen, Tun Chieh ^a,b,c   Hsu, Ya Ling ^c   Tsai, Yu Chieh ^c   Chang, Yu Wei ^c,d   Kuo, Po Lin ^b,c   Chen, Yen Hsu ^b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Breast cancer; Gemifloxacin; Metastasis; NF B; RKIP

Indexed keywords

GEMIFLOXACIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SNAIL; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL STRAIN MDA MB 231; CELL STRAIN MDA MB 453; CONTROLLED STUDY; DRUG EFFECT; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; METASTASIS INHIBITION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE MODELS, ANIMAL; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FLUOROQUINOLONES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NAPHTHYRIDINES; NEOPLASM METASTASIS; NF-KAPPA B; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; SIGNAL TRANSDUCTION; TOPOISOMERASE II INHIBITORS; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84891888381     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-013-1083-4     Document Type: Article

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