How cells feel: Stochastic model for a molecular mechanosensor

Biophysical Journal

Volumn 106, Issue 1, 2014, Pages 124-133

  Escudé, Matteo ^a   Rigozzi, Michelle K ^a   Terentjev, Eugene M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL ADHESION; FEEDBACK SYSTEM; MECHANOTRANSDUCTION; METABOLISM; MOTION; MYOFIBROBLAST; PHYSIOLOGY; STRESS FIBER;

ANIMALS; CELL ADHESION; FEEDBACK, PHYSIOLOGICAL; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; MOTION; MYOFIBROBLASTS; STRESS FIBERS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84891883521     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2013.10.042     Document Type: Article

References (41)

1. S. Sinha, and M. Hoofnagle G. Owens Transforming growth factor-β1 signaling contributes to development of smooth muscle cells from embryonic stem cells Am. J. Physiol. Cell Physiol. 287 2004 C1560 C1568
2. J. Solon, and I. Levental P. Janmey Fibroblast adaptation and stiffness matching to soft elastic substrates Biophys. J. 93 2007 4453 4461
3. T. Yeung, and P. Georges P. Janmey Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion Cell Motil. Cytoskeleton 60 2005 24 34
4. R. Pelham, and Y.-L. Wang Cell locomotion and focal adhesions are regulated by substrate flexibility Proc. Natl. Acad. Sci. USA 94 1997 13661 13665
5. M. Ghibaudo, and A. Saez B. Ladoux Traction forces and rigidity sensing regulate cell functions Soft Matter 4 2008 1836 1843
6. A. Engler, and S. Sen D. Discher Matrix elasticity directs stem cell lineage specification Cell 126 2006 677 689
7. P. Wipff, and D. Rifkin B. Hinz Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix J. Cell Biol. 179 2007 1311 1323
8. S. Sinha, and A. Heagerty C. Kielty Expression of latent TGF-β binding proteins and association with TGF-β1 and fibrillin-1 following arterial injury Cardiovasc. Res. 53 2002 971 983
9. C. Cheung, and A. Bernardo S. Sinha Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility Nat. Biotechnol. 15 2012 165 173
10. U. Schwarz, T. Erdmann, and I. Bischofs Focal adhesions as mechanosensors: the two-spring model Biosystems 83 2006 225 232
11. G. Bell Models for the specific adhesion of cells to cells Science 200 1978 618 627
12. H. Kramers Brownian motion in a field of force and the diffusion model of chemical reactions Physica 7 1940 284 304
13. O.K. Dudko, G. Hummer, and A. Szabo Intrinsic rates and activation free energies from single-molecule pulling experiments Phys. Rev. Lett. 96 2006 108101
14. M. Dembo, and Y. Wang Stresses at the cell-to-substrate interface during locomotion of fibroblasts Biophys. J. 76 1999 2307 2316
15. U. Schwarz, and D. Balaban S. Safran Calculation of forces at focal adhesions from elastic substrate Biophys. J. 83 2002 1380 1394
16. J. Tan, and J. Tien C. Chen Cells lying on a bed of microneedles: an approach to isolate mechanical force Proc. Natl. Acad. Sci. USA 100 2003 1484 1489
17. J. Tomasek, and G. Gabbiani R. Brown Myofibroblasts and mechano-regulation of connective tissue remodeling Nat. Rev. Mol. Cell Biol. 3 2002 349 363
18. B. Hinz Formation and function of the myofibroblast during tissue repair J. Invest. Dermatol. 127 2007 526 537
19. P. Arora, N. Narani, and C. McCulloch The compliance of collagen gels regulates transforming growth factor-β induction of α-smooth muscle actin in fibroblasts Am. J. Pathol. 154 1999 871-182
20. B. Hinz, and G. Celetta C. Chaponnier Alpha-smooth muscle actin expression upregulates fibroblast contractile activity Mol. Biol. Cell 12 2001 2730 2741
21. L. Buscemi, and D. Ramonet B. Hinz The single-molecule mechanics of the latent TGF-β1 complex Curr. Biol. 21 2011 2046 2054
22. P. Wells, and D. Discher Matrix elasticity, cytoskeletal tension, and TGF-β: the insoluble and soluble meet Sci. Signal. 1 2008 1 3
23. R. Graham Covariant formulation of non-equilibrium statistical thermodynamics Zeit. Phys. B 26 1977 397 405
24. S. Chandrasekhar Stochastic problems in physics and astronomy Rev. Mod. Phys. 15 1943 1 89
25. P. Hänggi, P. Talkner, and M. Borkovec Reaction rate theories: 50 years after Kramers Rev. Mod. Phys. 62 1990 251 340
26. S. Yohichi, and O.K. Dudko Single-molecule rupture dynamics on multidimensional landscapes Phys. Rev. Lett. 104 2010 048101
27. A.M. Berezhkovskii, V.Y. Zitserman, and A. Polimeno Numerical test of Kramers reaction rate theory in two dimensions J. Chem. Phys. 105 1996 6342 6357
28. J.S. Langer Statistical theory of the decay of metastable states Ann. Phys. 54 1969 258 275
29. G. Hummer, and A. Szabo Kinetics from nonequilibrium single-molecule pulling experiments Biophys. J. 85 2003 5 15
30. M.D. Brenner, R. Zhou, and T. Ha Forcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing Biopolymers 95 2011 332 344
31. T. Lecuit, P.F. Lenne, and E. Munro Force generation, transmission, and integration during cell and tissue morphogenesis Annu. Rev. Cell Dev. Biol. 27 2011 157 184
32. A.D. Bershadsky, N.Q. Balaban, and B. Geiger Adhesion-dependent cell mechanosensitivity Annu. Rev. Cell Dev. Biol. 19 2003 677 695
33. J.T. Finer, R.M. Simmons, and J.A. Spudich Single myosin molecular mechanics: picoNewton forces and nanometer steps Nature 368 1994 113 119
34. D.E. Ingber Mechanosensation through integrins: cells act locally but think globally Proc. Natl. Acad. Sci. USA 100 2003 1472 1474
35. A. Saez, and E. Anon B. Ladoux Traction forces exerted by epithelial cell sheets J. Phys. Cond. Mat. 22 2010 194119
36. L.D. Landau, and I.M. Lifshitz Theory of Elasticity 3rd Ed. 1986 Butterworth-Heinemann Oxford, UK
37. B. Cappella, and G. Dietler Force-distance curves by atomic force microscopy Surf. Sci. Rep. 34 1999 1 104
38. A. Saez, and A. Buguin B. Ladoux Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys. J. 89 2005 L52 L54
39. R. De, A. Zemel, and S.A. Safran Do cells sense stress or strain? Measurement of cellular orientation can provide a clue Biophys. J. 94 2008 L29 L31
40. T.M. Freyman, and I.V. Yannas L.J. Gibson Fibroblast contractile force is independent of the stiffness which resists the contraction Exp. Cell Res. 272 2002 153 162
41. M.B. Jackson Molecular and Cellular Biophysics 2006 Cambridge University Press Cambridge, UK