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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 2, 2014, Pages 591-594

Design, synthesis and in vitro cytotoxicity evaluation of 5-(2-carboxyethenyl)isatin derivatives as anticancer agents

(11) Han, Kailin a Zhou, Yao a Liu, Fengxi a Guo, Qiannan a Wang, Pengfei a Yang, Yao a Song, Binbin a Liu, Wei a Yao, Qingwei b Teng, Yuou a Yu, Peng a

a TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY (China)

b Chemo Dynamics Inc (United States)

Author keywords

Antitumor activity; In vitro cytotoxicity; Isatin derivatives

Indexed keywords

5 (2 CARBOXYETHENYL)ISATIN DERIVATIVE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CARBONYL DERIVATIVE; ISATIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LEUKEMIA CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MTT ASSAY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTITUMOR ACTIVITY; IN VITRO CYTOTOXICITY; ISATIN DERIVATIVES;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CYTOTOXINS; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HT29 CELLS; HUMANS; K562 CELLS;

EID: 84891861316 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.12.001 Document Type: Article

Times cited : (66)

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