QSAR study of isatin analogues as in vitro anti-cancer agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1113-1118

  Sabet, Razieh ^a   Mohammadpour, Mehrdad ^a   Sadeghi, Amir ^a   Fassihi, Afshin ^a,b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Isfahan Pharmaceutical Sciences Research Center   (Iran)

Author keywords

Anti cancer; GA PLS; Isatin derivatives; MLR; QSAR

Indexed keywords

ANTINEOPLASTIC AGENT; HALOGEN; ISATIN DERIVATIVE; KETONE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG STRUCTURE; GENETIC ALGORITHM; IN VITRO STUDY; LIPOPHILICITY; MULTIPLE LINEAR REGRESSION ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DESIGN; HUMANS; ISATIN; LINEAR MODELS; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 75849132121     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.010     Document Type: Article

References (31)

1. Pandeya S.N., Smitha S., Jyoti M., and Sridhar S.K. Acta Pharm. 55 (2005) 27-46
2. Sharma V.M., Prasanna P., Seshu V.A., Renuka B., Rao V.L., Kumar G.S., Narasimhulu C.P., Babu P.A., Puranik R.C., Subramanyam D., Venkateswarlu A., Rajagopal S., Kumar K.B.S., Rao C.S., Mamidi N.V.S.R., Deevi D.S., Ajaykumar R., and Rajagopalan R. Bioorg. Med. Chem. Lett. 12 (2002) 2303-2307
3. Moon M.J., Lee S.K., Lee J.W., Song W.K., Kim S.W., Kim J.I., Cho C., Choi S.J., and Kim Y.C. Bioorg. Med. Chem. 14 (2006) 237-246
4. Abadi A.H., Abou-Seri S.M., Abdel-Rahman D.E., Klein C., Lozach O., and Meijer L. Eur. J. Med. Chem. 41 (2006) 296-305
5. Gursoy A., and Karali N. Eur. J. Med. Chem. 38 (2003) 633-643
6. Esheba N.H., and Salama H.M. Pharmazie 40 (1985) 320-322
7. Popp F.D., and Pajouhesh H. J. Pharm. Sci. 72 (1983) 318-321
8. Westley C.B., Vine K.L., and Benkendorff K. In: Meijer L., Guyard N., Skaltsounis L.A., and Eisenbrand G. (Eds). Indirubin, the Red Shade of Indigo; Life in Progress Editions, France (2006) 31-44
9. Benkendorff K., Bremner J., and Davis A. Molecules 6 (2001) 70-78
10. Vine K.L., Locke J.M., Ranson M., Benkendorff K., Pyne S.G., and Bremner J.B. Bioorg. Med. Chem. 15 (2007) 931-938
11. Vine K.L., Locke J.M., Ranson M., Pyne S.G., and Bremner J.B. J. Med. Chem. 50 (2007) 5109-5117
12. Matesic L., Locke J.M., Bremner J.B., Pyne S.G., Skropeta D., Ranson M., and Vine K.L. Bioorg. Med. Chem. 16 (2008) 3118-3124
13. Prenen H., Cools J., Mentens N., Folens C., Sciot R., Schoffski P., Van Oosterom A., Marynen P., and Debiec-Rychter M. Clin. Cancer Res. 8 (2006) 2622-2627
14. Motzer R.J., Michaelson M.D., Redman B.G., Hudes G.R., Wilding G., Figlin R.A., Ginsberg M.S., Kim S.T., Baum C.M., DePrimo S.E., Li J.Z., Bello C.L., Theuer C.P., George D.J., and Rini B.I. J. Clin. Oncol. 24 (2006) 16-24
15. Hansch C., Hoekman D., and Gao H. Chem. Rev. 96 (1996) 1045-1075
16. Schmidi H. Chemom. Intell. Lab. Syst. 37 (1997) 125-136
17. Hansch C.A., Kurup A., Garg R., and Gao H. Chem. Rev. 101 (2001) 619-672
18. Wold S., Trygg J., Berglund A., and Antii H. Chemom. Intell. Lab. Syst. 58 (2001) 131-150
19. Hemmateenejad B., Miri R., Akhond M., and Shamsipur M. Chemom. Intell. Lab. Syst. 64 (2002) 91-99
20. Hemmateenejad B., Miri R., Akhond M., and Shamsipur M. Arch. Pharm. Pharm. Med. Chem. 10 (2002) 472-480
21. Sabet R., and Fassihi A. Int. J. Mol. Sci. 9 (2008) 2407-2423
22. Fassihi A., and Sabet R. Int. J. Mol. Sci. 9 (2008) 1876-1892
23. Fassihi A., Abedi D., Saghaie L., Sabet R., Fazeli H., Bostaki G., Deilami O., and Sadinpour H. Eur. J. Med. Chem. (2008) 10.1016/j.ejmech.2008.10.022
24. Consonni V., Todeschini R., and Pavan M. J. Chem. Inf. Comput. Sci. 42 (2002) 693-705
25. HyperChem, Release 7.0 for Windows, Molecular Modeling System: HyperCube, 2002.
26. Visit the Hyperchem official website at: http://www.hyper.com.
27. R. Todeschini, Milano Chemometrics and QSAR Group. http://michem.disat.unimib.it (accessed 9.9.08).
28. Frisch M.J., Trucks M.J., Schlegel H.B., Scuseria G.E., Robb M.A., Cheeseman J.R., Zakrzewski V.G., et al. Gaussian 98, Revision A.7 (1998), Gaussian, Inc, Pittsburgh PA
29. Thanikaivelan P., Subramanian V., Rao J.R., and Nair B.U. Chem. Phys. Lett. 323 (2000) 59-70
30. Hansch C., Leo A., and Taft R.W. Chem. Rev. 91 (1991) 165-195
31. Hemmateenejad B. J. Chemomet. 18 (2004) 475-485