메뉴 건너뛰기




Volumn 25, Issue 1, 2014, Pages 32-43

Caffeine induces behavioural sensitization and overexpression of cocaine-regulated and amphetamine-regulated transcript peptides in mice

Author keywords

A1 and A2A receptors; behavioural sensitization; caffeine; CART; D1 and D2 receptors; mice striatum; mouse

Indexed keywords

4 [2 [(6 AMINO 9 (N ETHYL BETA DEXTRO RIBOFURANURONAMIDOSYL) 9H PURIN 2 YL)AMINO]ETHYL]BENZENEOPROPANOIC ACID HYDROCHLORIDE; 6 N CYCLOPENTYLADENOSINE; 7 CHLORO 8 HYDROXY 3 METHYL 1 PHENYL 2,3,4,5 TETRAHYDRO 1H 3 BENZAZEPINE HYDROCHLORIDE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; CAFFEINE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; MESSENGER RNA; RACLOPRIDE; UNCLASSIFIED DRUG;

EID: 84891859280     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0000000000000016     Document Type: Article
Times cited : (8)

References (44)
  • 1
    • 16444381703 scopus 로고    scopus 로고
    • Caffeine and the dopaminergic system
    • DOI 10.1097/00008877-200503000-00001
    • Cauli O, Morelli M (2005). Caffeine and the dopaminergic system. Behav Pharmacol 16:63-77. (Pubitemid 40477532)
    • (2005) Behavioural Pharmacology , vol.16 , Issue.2 , pp. 63-77
    • Cauli, O.1    Morelli, M.2
  • 2
    • 0022559179 scopus 로고
    • C-ras(H) and ornithine decarboxylase are induced by oestradiol-17β in the mouse uterine luminal epithelium independently of the proliferative status of the cell
    • DOI 10.1016/0014-5793(86)80269-1
    • Cheng SV, Pollard JW (1986). c-rasH and ornithine decarboxylase are induced by oestradiol-17 beta in the mouse uterine luminal epithelium independently of the proliferative status of the cell. FEBS Lett 196:309-314. (Pubitemid 16047483)
    • (1986) FEBS Letters , vol.196 , Issue.2 , pp. 309-314
    • Cheng, S.V.Y.1    Pollard, J.W.2
  • 3
    • 0035927217 scopus 로고    scopus 로고
    • CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat
    • Dallvechia-Adams S, Smith Y, Kuhar MJ (2001). CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat. J Comp Neurol 434:29-39.
    • (2001) J Comp Neurol , vol.434 , pp. 29-39
    • Dallvechia-Adams, S.1    Smith, Y.2    Kuhar, M.J.3
  • 4
    • 0037043161 scopus 로고    scopus 로고
    • Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: Colocalization with γ-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons
    • DOI 10.1002/cne.10268
    • Dallvechia-Adams S, Kuhar MJ, Smith Y (2002). Cocaine-and amphetamineregulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons. J Comp Neurol 448: 360-372. (Pubitemid 34569184)
    • (2002) Journal of Comparative Neurology , vol.448 , Issue.4 , pp. 360-372
    • Dallvechia-Adams, S.1    Kuhar, M.J.2    Smith, Y.3
  • 5
    • 0028947053 scopus 로고
    • PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine
    • Douglass J, McKinzie AA, Couceyro P (1995). PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J Neurosci 15:2471-2481.
    • (1995) J Neurosci , vol.15 , pp. 2471-2481
    • Douglass, J.1    McKinzie, A.A.2    Couceyro, P.3
  • 6
    • 0028338738 scopus 로고
    • Caffeine reinforcement demonstrated in a majority of moderate caffeine users
    • Evans SM, Critchfield TS, Griffiths RR (1994). Caffeine reinforcement demonstrated in a majority of moderate caffeine users. Behav Pharmacol 5: 231-238. (Pubitemid 24217285)
    • (1994) Behavioural Pharmacology , vol.5 , Issue.3 , pp. 231-238
    • Evans, S.M.1    Critchfield, T.S.2    Griffiths, R.R.3
  • 7
    • 33746028222 scopus 로고    scopus 로고
    • Neuroendocrine implications for the association between cocaine- and amphetamine regulated transcript (CART) and hypophysiotropic thyrotropin-releasing hormone (TRH)
    • DOI 10.1016/j.peptides.2005.11.029, PII S0196978106002130
    • Fekete C, Lechan RM (2006). Neuroendocrine implications for the association between cocaine-and amphetamine-regulated transcript (CART) and hypophysiotropic thyrotropin-releasing hormone (TRH). Peptides 27: 2012-2018. (Pubitemid 44067295)
    • (2006) Peptides , vol.27 , Issue.8 , pp. 2012-2018
    • Fekete, C.1    Lechan, R.M.2
  • 9
    • 77956216026 scopus 로고    scopus 로고
    • Role of the central ascending neurotransmitter systems in the psychostimulant effects of caffeine
    • Ferre S (2010). Role of the central ascending neurotransmitter systems in the psychostimulant effects of caffeine. J Alzheimers Dis 20 (Suppl 1): S35-S49.
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 1
    • Ferre, S.1
  • 11
    • 34547954723 scopus 로고    scopus 로고
    • Time course effects of adrenalectomy and food intake on cocaine- and amphetamine-regulated transcript expression in the hypothalamus
    • DOI 10.1016/j.brainres.2007.05.077, PII S0006899307012589
    • Germano CM, de Castro M, Rorato R, Laguna MT, Antunes-Rodrigues J, Elias CF, Elias LL (2007). Time course effects of adrenalectomy and food intake on cocaine-and amphetamine-regulated transcript expression in the hypothalamus. Brain Res 1166:55-64. (Pubitemid 47268304)
    • (2007) Brain Research , vol.1166 , Issue.1 , pp. 55-64
    • Germano, C.M.R.1    De Castro, M.2    Rorato, R.3    Laguna, M.T.C.4    Antunes-Rodrigues, J.5    Elias, C.F.6    Elias, L.L.K.7
  • 13
    • 33750947281 scopus 로고    scopus 로고
    • Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens
    • DOI 10.1016/j.npep.2006.09.001, PII S0143417906000679
    • Hubert GW, Kuhar MJ (2006). Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens. Neuropeptides 40:409-415. (Pubitemid 44738020)
    • (2006) Neuropeptides , vol.40 , Issue.6 , pp. 409-415
    • Hubert, G.W.1    Kuhar, M.J.2
  • 14
    • 70449626835 scopus 로고    scopus 로고
    • Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion
    • Hubert GW, Manvich DF, Kuhar MJ (2010). Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion. Neuroscience 165:179-187.
    • (2010) Neuroscience , vol.165 , pp. 179-187
    • Hubert, G.W.1    Manvich, D.F.2    Kuhar, M.J.3
  • 15
    • 33645305508 scopus 로고    scopus 로고
    • Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors
    • DOI 10.1016/j.neuropharm.2005.12.007, PII S0028390805004181
    • Hunter RG, Jones D, Vicentic A, Hue G, Rye D, Kuhar MJ (2006). Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors. Neuropharmacology 50:858-864. (Pubitemid 43737003)
    • (2006) Neuropharmacology , vol.50 , Issue.7 , pp. 858-864
    • Hunter, R.G.1    Jones, D.2    Vicentic, A.3    Hue, G.4    Rye, D.5    Kuhar, M.J.6
  • 16
    • 33746020896 scopus 로고    scopus 로고
    • The role of CART in the reward/reinforcing properties of psychostimulants
    • DOI 10.1016/j.peptides.2006.03.034, PII S0196978106002117
    • Jaworski JN, Jones DC (2006). The role of CART in the reward/reinforcing properties of psychostimulants. Peptides 27:1993-2004. (Pubitemid 44067293)
    • (2006) Peptides , vol.27 , Issue.8 , pp. 1993-2004
    • Jaworski, J.N.1    Jones, D.C.2
  • 17
    • 0344304802 scopus 로고    scopus 로고
    • Intra-Accumbal Injection of CART (Cocaine-Amphetamine Regulated Transcript) Peptide Reduces Cocaine-Induced Locomotor Activity
    • DOI 10.1124/jpet.103.052332
    • Jaworski JN, Kozel MA, Philpot KB, Kuhar MJ (2003). Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaineinduced locomotor activity. J Pharmacol Exp Ther 307:1038-1044. (Pubitemid 37494223)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.307 , Issue.3 , pp. 1038-1044
    • Jaworski, J.N.1    Kozel, M.A.2    Philpot, K.B.3    Kuhar, M.J.4
  • 18
    • 33847272036 scopus 로고    scopus 로고
    • Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: An isobolographic analysis
    • DOI 10.1016/j.npep.2006.12.003, PII S0143417906001545
    • Jaworski JN, Kimmel HL, Mitrano DA, Tallarida RJ, Kuhar MJ (2007). Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: an isobolographic analysis. Neuropeptides 41:65-72. (Pubitemid 46329100)
    • (2007) Neuropeptides , vol.41 , Issue.2 , pp. 65-72
    • Jaworski, J.N.1    Kimmel, H.L.2    Mitrano, D.A.3    Tallarida, R.J.4    Kuhar, M.J.5
  • 19
    • 33645115840 scopus 로고    scopus 로고
    • Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5'-monophosphate/protein kinase a second messenger system
    • Jones DC, Kuhar MJ (2006). Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5'-monophosphate/protein kinase a second messenger system. J Pharmacol Exp Ther 317:454-461.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 454-461
    • Jones, D.C.1    Kuhar, M.J.2
  • 20
    • 50449092991 scopus 로고    scopus 로고
    • Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner
    • Jones FS, Jing J, Stonehouse AH, Stevens A, Edelman GM (2008). Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner. Mol Pharmacol 74:673-684.
    • (2008) Mol Pharmacol , vol.74 , pp. 673-684
    • Jones, F.S.1    Jing, J.2    Stonehouse, A.H.3    Stevens, A.4    Edelman, G.M.5
  • 21
    • 58149145445 scopus 로고    scopus 로고
    • Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity
    • Kaplan GB, Leite-Morris KA, Klufas MA, Fan WY (2009). Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity. Eur J Pharmacol 602:268-276.
    • (2009) Eur J Pharmacol , vol.602 , pp. 268-276
    • Kaplan, G.B.1    Leite-Morris, K.A.2    Klufas, M.A.3    Fan, W.Y.4
  • 23
    • 0141831860 scopus 로고    scopus 로고
    • Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos
    • Karcz-Kubicha M, Quarta D, Hope BT, Antoniou K, Muller CE, Morales M (2003b). Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos. Eur J Neurosci 18:296-302.
    • (2003) Eur J Neurosci , vol.18 , pp. 296-302
    • Karcz-Kubicha, M.1    Quarta, D.2    Hope, B.T.3    Antoniou, K.4    Muller, C.E.5    Morales, M.6
  • 24
    • 33748783064 scopus 로고    scopus 로고
    • Stimulation of adenosine receptors selectively activates gene expression in striatal enkephalinergic neurons
    • DOI 10.1038/sj.npp.1301035, PII 1301035
    • Karcz-Kubicha M, Ferre S, Diaz-Ruiz O, Quiroz C, Goldberg SR, Hope BT, Morales M (2006). Stimulation of adenosine receptors selectively activates gene expression in striatal enkephalinergic neurons. Neuropsychopharmacology 31:2173-2179. (Pubitemid 44413194)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2173-2179
    • Karcz-Kubicha, M.1    Ferre, S.2    Diaz-Ruiz, O.3    Quiroz-Molina, C.4    Goldberg, S.R.5    Hope, B.T.6    Morales, M.7
  • 26
    • 0017638142 scopus 로고
    • Reverse tolerance to stimulant-induced abnormal behavior
    • Kilbey MM, Ellinwood EH Jr (1977). Reverse tolerance to stimulant-induced abnormal behavior. Life Sci 20:1063-1075.
    • (1977) Life Sci , vol.20 , pp. 1063-1075
    • Kilbey, M.M.1    Ellinwood Jr., E.H.2
  • 27
    • 0024545499 scopus 로고
    • Reverse tolerance to ambulation-increasing effects of methamphetamine and morphine in 6 mouse strains
    • Kuribara H, Tadokoro S (1989). Reverse tolerance to ambulation-increasing effects of methamphetamine and morphine in 6 mouse strains. Jpn J Pharmacol 49:197-203. (Pubitemid 19064599)
    • (1989) Japanese Journal of Pharmacology , vol.49 , Issue.2 , pp. 197-203
    • Kirubara, H.1    Tadokoro, S.2
  • 28
    • 80052953761 scopus 로고    scopus 로고
    • Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: In vivo optical microprobe [Ca2+]i imaging
    • Luo Z, Volkow ND, Heintz N, Pan Y, Du C (2011). Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging. J Neurosci 31:13180-13190.
    • (2011) J Neurosci , vol.31 , pp. 13180-13190
    • Luo, Z.1    Volkow, N.D.2    Heintz, N.3    Pan, Y.4    Du, C.5
  • 29
    • 78049411734 scopus 로고    scopus 로고
    • CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors
    • Moffett MC, Song J, Kuhar MJ (2011). CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse 65:1-7.
    • (2011) Synapse , vol.65 , pp. 1-7
    • Moffett, M.C.1    Song, J.2    Kuhar, M.J.3
  • 30
    • 0036385312 scopus 로고    scopus 로고
    • Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity
    • Poleszak E, Malec D (2002). Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity. Pol J Pharmacol 54:359-366.
    • (2002) Pol J Pharmacol , vol.54 , pp. 359-366
    • Poleszak, E.1    Malec, D.2
  • 31
    • 0022725590 scopus 로고
    • Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
    • DOI 10.1016/0165-0173(86)90002-0
    • Robinson TE, Becker JB (1986). Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res 396:157-198. (Pubitemid 16100809)
    • (1986) Brain Research Reviews , vol.11 , Issue.2 , pp. 157-198
    • Robinson, T.E.1    Becker, J.B.2
  • 32
    • 58149378135 scopus 로고    scopus 로고
    • Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo
    • Rogge GA, Jones DC, Green T, Nestler E, Kuhar MJ (2009). Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain Res 1251:42-52.
    • (2009) Brain Res , vol.1251 , pp. 42-52
    • Rogge, G.A.1    Jones, D.C.2    Green, T.3    Nestler, E.4    Kuhar, M.J.5
  • 33
    • 68949146848 scopus 로고    scopus 로고
    • Up-regulation of cocaine-and amphetamine-regulated transcript (CART) in the rat nucleus accumbens after repeated electroconvulsive shock
    • Roh MS, Cui FJ, Ahn YM, Kang UG (2009). Up-regulation of cocaine-and amphetamine-regulated transcript (CART) in the rat nucleus accumbens after repeated electroconvulsive shock. Neurosci Res 65:210-213.
    • (2009) Neurosci Res , vol.65 , pp. 210-213
    • Roh, M.S.1    Cui, F.J.2    Ahn, Y.M.3    Kang, U.G.4
  • 34
    • 25844500359 scopus 로고    scopus 로고
    • Adenosine-dopamine interactions revealed in knockout mice
    • DOI 10.1385/JMN:26:2-3:239
    • Salmi P, Chergui K, Fredholm BB (2005). Adenosine-dopamine interactions revealed in knockout mice. J Mol Neurosci 26:239-244. (Pubitemid 41389416)
    • (2005) Journal of Molecular Neuroscience , vol.26 , Issue.2-3 , pp. 239-244
    • Salmi, P.1    Chergui, K.2    Fredholm, B.B.3
  • 35
    • 0021849916 scopus 로고
    • Determination of cyclic AMP-dependent protein kinase subunits by an immunoassay reveals a different subcellular distribution of the enzyme in rat parotid than does determination of the enzyme activity
    • Schwoch G, Lohmann SM, Walter U, Jung U (1985). Determination of cyclic AMP-dependent protein kinase subunits by an immunoassay reveals a different subcellular distribution of the enzyme in rat parotid than does determination of the enzyme activity. J Cyclic Nucleotide Protein Phosphor Res 10:247-258. (Pubitemid 15033644)
    • (1985) Journal of Cyclic Nucleotide and Protein Phosphorylation Research , vol.10 , Issue.3 , pp. 247-258
    • Schwoch, G.1    Lohmann, S.M.2    Walter, U.3    Jung, U.4
  • 36
    • 33745868024 scopus 로고    scopus 로고
    • Sensitization to caffeine and cross-sensitization to amphetamine: Influence of individual response to caffeine
    • DOI 10.1016/j.bbr.2006.04.019, PII S0166432806002130
    • Simola N, Cauli O, Morelli M (2006). Sensitization to caffeine and crosssensitization to amphetamine: influence of individual response to caffeine. Behav Brain Res 172:72-79. (Pubitemid 44037812)
    • (2006) Behavioural Brain Research , vol.172 , Issue.1 , pp. 72-79
    • Simola, N.1    Cauli, O.2    Morelli, M.3
  • 37
    • 0037441837 scopus 로고    scopus 로고
    • Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs
    • DOI 10.1016/S0006-3223(02)01574-3, PII S0006322303015743
    • Singewald N, Salchner P, Sharp T (2003). Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs. Biol Psychiatry 53:275-283. (Pubitemid 36175541)
    • (2003) Biological Psychiatry , vol.53 , Issue.4 , pp. 275-283
    • Singewald, N.1    Salchner, P.2    Sharp, T.3
  • 38
    • 0030725631 scopus 로고    scopus 로고
    • Caffeine mimics the effect of a dopamine D(2/3) receptor agonist on the expression of immediate early genes in globus pallidus
    • DOI 10.1016/S0028-3908(97)00091-9, PII S0028390897000919
    • Svenningsson P, Fredholm BB (1997). Caffeine mimics the effect of a dopamine D2/3 receptors agonist on the expression of agonist on the expression of immediate early genes in globus pallidus. Neuropharmacology 36:1309-1317. (Pubitemid 27465619)
    • (1997) Neuropharmacology , vol.36 , Issue.9 , pp. 1309-1317
    • Svenningsson, P.1    Fredholm, B.B.2
  • 39
    • 0032029264 scopus 로고    scopus 로고
    • Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat
    • DOI 10.1016/S0028-3908(98)00045-8, PII S0028390898000458
    • Svenningsson P, Nergardh R, Fredholm BB (1998). Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat. Neuropharmacology 37:331-337. (Pubitemid 28282638)
    • (1998) Neuropharmacology , vol.37 , Issue.3 , pp. 331-337
    • Svenningsson, P.1    Nergardh, R.2    Fredholm, B.B.3
  • 40
    • 0032781426 scopus 로고    scopus 로고
    • Distribution, biochemistry and function of striatal adenosine A(2A) receptors
    • DOI 10.1016/S0301-0082(99)00011-8, PII S0301008299000118
    • Svenningsson P, Le Moine C, Fisone G, Fredholm BB (1999). Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol 59:355-396. (Pubitemid 29352341)
    • (1999) Progress in Neurobiology , vol.59 , Issue.4 , pp. 355-396
    • Svenningsson, P.1    Le Moine, C.2    Fisone, G.3    Fredholm, B.B.4
  • 41
    • 77956400185 scopus 로고    scopus 로고
    • CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment
    • Tanegashima K, Okamoto S, Nakayama Y, Taya C, Shitara H, Ishii R, et al. (2010). CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment. PLoS One 5:e10321.
    • (2010) PLoS One , vol.5
    • Tanegashima, K.1    Okamoto, S.2    Nakayama, Y.3    Taya, C.4    Shitara, H.5    Ishii, R.6
  • 42
    • 84864118581 scopus 로고    scopus 로고
    • Caffeine increases psychomotor performance on the effort expenditure for rewards task
    • Wardle MC, Treadway MT, de Wit H (2012). Caffeine increases psychomotor performance on the effort expenditure for rewards task. Pharmacol Biochem Behav 102:526-531.
    • (2012) Pharmacol Biochem Behav , vol.102 , pp. 526-531
    • Wardle, M.C.1    Treadway, M.T.2    De Wit, H.3
  • 44
    • 80053221873 scopus 로고    scopus 로고
    • Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice
    • Zeitlin R, Patel S, Burgess S, Arendash GW, Echeverria V (2011). Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice. Brain Res 1417: 127-136.
    • (2011) Brain Res , vol.1417 , pp. 127-136
    • Zeitlin, R.1    Patel, S.2    Burgess, S.3    Arendash, G.W.4    Echeverria, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.