메뉴 건너뛰기




Volumn 8, Issue 12, 2013, Pages

Elevated alanine aminotransferase is strongly associated with incident metabolic syndrome: A meta-analysis of prospective studies

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE;

EID: 84891854434     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080596     Document Type: Article
Times cited : (31)

References (68)
  • 3
    • 77949430552 scopus 로고    scopus 로고
    • Metabolic syndrome as a risk factor for diabetes
    • Aschner P (2010) Metabolic syndrome as a risk factor for diabetes. Expert Review of Cardiovascular Therapy 8: 407-412.
    • (2010) Expert Review of Cardiovascular Therapy , vol.8 , pp. 407-412
    • Aschner, P.1
  • 4
    • 33846365989 scopus 로고    scopus 로고
    • Metabolic Syndrome and Risk of Incident Cardiovascular Events and DeathA Systematic Review and Meta-Analysis of Longitudinal Studies
    • Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, et al. (2007) Metabolic Syndrome and Risk of Incident Cardiovascular Events and DeathA Systematic Review and Meta-Analysis of Longitudinal Studies. Journal of the American College of Cardiology 49: 403-414.
    • (2007) Journal of the American College of Cardiology , vol.49 , pp. 403-414
    • Gami, A.S.1    Witt, B.J.2    Howard, D.E.3    Erwin, P.J.4    Gami, L.A.5
  • 5
    • 77955549859 scopus 로고    scopus 로고
    • Metabolic syndrome and all-cause mortality: A meta-analysis of prospective cohort studies
    • Hui WS, Liu Z, Ho SC (2010) Metabolic syndrome and all-cause mortality: a meta-analysis of prospective cohort studies. European journal of epidemiology 25: 375-384.
    • (2010) European Journal of Epidemiology , vol.25 , pp. 375-384
    • Hui, W.S.1    Liu, Z.2    Ho, S.C.3
  • 6
    • 4744339348 scopus 로고    scopus 로고
    • Obesity: The worldwide epidemic
    • James PT (2004) Obesity: the worldwide epidemic. Clinics in dermatology 22: 276-280.
    • (2004) Clinics in Dermatology , vol.22 , pp. 276-280
    • James, P.T.1
  • 8
    • 0035431018 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease a feature of the metabolic syndrome
    • Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, et al. (2001) Nonalcoholic fatty liver disease a feature of the metabolic syndrome. Diabetes 50: 1844-1850.
    • (2001) Diabetes , vol.50 , pp. 1844-1850
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3    Tomassetti, S.4    Bugianesi, E.5
  • 9
    • 0034831067 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Reid AE (2001) Nonalcoholic steatohepatitis. Gastroenterology 121: 710-723.
    • (2001) Gastroenterology , vol.121 , pp. 710-723
    • Reid, A.E.1
  • 10
    • 0037382786 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    • Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, et al. (2003) Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 37: 917-923.
    • (2003) Hepatology , vol.37 , pp. 917-923
    • Marchesini, G.1    Bugianesi, E.2    Forlani, G.3    Cerrelli, F.4    Lenzi, M.5
  • 11
    • 2542498253 scopus 로고    scopus 로고
    • Serum γ-glutamyltransferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men
    • Nakanishi N, Suzuki K, Tatara K (2004) Serum γ-glutamyltransferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men. Diabetes Care 27: 1427-1432.
    • (2004) Diabetes Care , vol.27 , pp. 1427-1432
    • Nakanishi, N.1    Suzuki, K.2    Tatara, K.3
  • 12
    • 33644693579 scopus 로고    scopus 로고
    • Liver Markers and Development of the Metabolic Syndrome The Insulin Resistance Atherosclerosis Study
    • Hanley AJ, Williams K, Festa A, Wagenknecht LE, D'Agostino RB, et al. (2005) Liver Markers and Development of the Metabolic Syndrome The Insulin Resistance Atherosclerosis Study. Diabetes 54: 3140-3147.
    • (2005) Diabetes , vol.54 , pp. 3140-3147
    • Hanley, A.J.1    Williams, K.2    Festa, A.3    Wagenknecht, L.E.4    D'Agostino, R.B.5
  • 13
    • 34548381151 scopus 로고    scopus 로고
    • γ-Glutamyltransferase Activity and Development of the Metabolic Syndrome (International Diabetes Federation Definition) in Middle-Aged Men and Women Data From the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort
    • André P, Balkau B, Vol S, Charles MA, Eschwège E (2007) γ-Glutamyltransferase Activity and Development of the Metabolic Syndrome (International Diabetes Federation Definition) in Middle-Aged Men and Women Data From the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Diabetes Care 30: 2355-2361.
    • (2007) Diabetes Care , vol.30 , pp. 2355-2361
    • André, P.1    Balkau, B.2    Vol, S.3    Charles, M.A.4    Eschwège, E.5
  • 14
    • 33947366047 scopus 로고    scopus 로고
    • Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: The Hoorn Study
    • Schindhelm R, Dekker J, Nijpels G, Stehouwer C, Bouter L, et al. (2007) Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: the Hoorn Study. Diabetic medicine 24: 430-435.
    • (2007) Diabetic Medicine , vol.24 , pp. 430-435
    • Schindhelm, R.1    Dekker, J.2    Nijpels, G.3    Stehouwer, C.4    Bouter, L.5
  • 15
    • 57349163062 scopus 로고    scopus 로고
    • Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease
    • Goessling W, Massaro JM, Vasan RS, D'Agostino Sr RB, Ellison RC, et al. (2008) Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology 135: 1935.
    • (2008) Gastroenterology , vol.135 , pp. 1935
    • Goessling, W.1    Massaro, J.M.2    Vasan, R.S.3    D'Agostino Sr., R.B.4    Ellison, R.C.5
  • 16
    • 64849089976 scopus 로고    scopus 로고
    • Serum γ-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria
    • Jo S-K, Lee W-Y, Rhee E-J, Won J-C, Jung C-H, et al. (2009) Serum γ-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria. Clinica Chimica Acta 403: 234-240.
    • (2009) Clinica Chimica Acta , vol.403 , pp. 234-240
    • Jo, S.-K.1    Lee, W.-Y.2    Rhee, E.-J.3    Won, J.-C.4    Jung, C.-H.5
  • 17
    • 79951796706 scopus 로고    scopus 로고
    • Cross: 234-240. and longitudinal association of serum alanine aminotransaminase and γ-glutamyl transferase act metabolic syndrome in middleassociand elderly Chinese people
    • XU Y, XU M, HUANG Y, NING G (2011) Cross: 234-240. and longitudinal association of serum alanine aminotransaminase and γ-glutamyl transferase act metabolic syndrome in middleassociand elderly Chinese people. Journal of Diabetes 3: 38-47.
    • (2011) Journal of Diabetes , vol.3 , pp. 38-47
    • Xu, Y.1    Xu, M.2    Huang, Y.3    Ning, G.4
  • 18
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of internal medicine 151: 264-269.
    • (2009) Annals of Internal Medicine , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 20
    • 58149412516 scopus 로고
    • Weighted kappa: Nominal scale agreement provision for scaled disagreement or partial credit
    • Cohen J (1968) Weighted kappa: Nominal scale agreement provision for scaled disagreement or partial credit. Psychological bulletin 70: 213.
    • (1968) Psychological Bulletin , vol.70 , pp. 213
    • Cohen, J.1
  • 23
    • 0026777701 scopus 로고
    • Methods for trend estimation from summarized dose-response data, with applications to meta-analysis
    • Greenland S, Longnecker MP (1992) Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. American Journal of Epidemiology 135: 1301-1309.
    • (1992) American Journal of Epidemiology , vol.135 , pp. 1301-1309
    • Greenland, S.1    Longnecker, M.P.2
  • 24
    • 33646496189 scopus 로고    scopus 로고
    • Generalized least squares for trend estimation of summarized dose-response data
    • Orsini N, Bellocco R, Greenland S (2006) Generalized least squares for trend estimation of summarized dose-response data. Stata Journal 6: 40-57.
    • (2006) Stata Journal , vol.6 , pp. 40-57
    • Orsini, N.1    Bellocco, R.2    Greenland, S.3
  • 25
  • 28
    • 0034823867 scopus 로고    scopus 로고
    • Funnel plots for detecting bias in meta-analysis-Guidelines on choice of axis
    • Sterne JA, Egger M (2001) Funnel plots for detecting bias in meta-analysis-Guidelines on choice of axis. Journal of clinical epidemiology 54: 1046-1055.
    • (2001) Journal of Clinical Epidemiology , vol.54 , pp. 1046-1055
    • Sterne, J.A.1    Egger, M.2
  • 29
    • 0035897696 scopus 로고    scopus 로고
    • EVALUATION, AND TREATMENT OF HIGH BLOOD CHOLESTEROL IN ADULTS. Executive summary of the third report of The National Cholesterol Education Program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Detection EPO
    • Detection EPO (2001) EVALUATION, AND TREATMENT OF HIGH BLOOD CHOLESTEROL IN ADULTS. Executive summary of the third report of The National Cholesterol Education Program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Jama 285: 2486-2497.
    • (2001) Jama , vol.285 , pp. 2486-2497
  • 30
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome - A new worldwide definition
    • Alberti K, Zimmet P, Shaw J (2005) The metabolic syndrome-a new worldwide definition. Lancet 366: 1059.
    • (2005) Lancet , vol.366 , pp. 1059
    • Alberti, K.1    Zimmet, P.2    Shaw, J.3
  • 31
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome an American Heart Association/National Heart, Lung, and Blood Institute scientific statement
    • Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, et al. (2005) Diagnosis and management of the metabolic syndrome an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 112: 2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4    Eckel, R.H.5
  • 32
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
    • Alberti K, Zimmet P (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabetic medicine 15: 539-553.
    • (1998) Diabetic Medicine , vol.15 , pp. 539-553
    • Alberti, K.1    Zimmet, P.2
  • 33
    • 33646547644 scopus 로고    scopus 로고
    • Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States
    • Ioannou GN, Weiss NS, Boyko EJ, Mozaffarian D, Lee SP (2006) Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States. Hepatology 43: 1145-1151.
    • (2006) Hepatology , vol.43 , pp. 1145-1151
    • Ioannou, G.N.1    Weiss, N.S.2    Boyko, E.J.3    Mozaffarian, D.4    Lee, S.P.5
  • 34
    • 0034720287 scopus 로고    scopus 로고
    • Evaluation of abnormal liver-enzyme results in asymptomatic patients
    • Pratt DS, Kaplan MM (2000) Evaluation of abnormal liver-enzyme results in asymptomatic patients. New England Journal of Medicine 342: 1266-1271.
    • (2000) New England Journal of Medicine , vol.342 , pp. 1266-1271
    • Pratt, D.S.1    Kaplan, M.M.2
  • 35
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM (2003) The prevalence and etiology of elevated aminotransferase levels in the United States. The American journal of gastroenterology 98: 960-967.
    • (2003) The American Journal of Gastroenterology , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 36
    • 6844258880 scopus 로고    scopus 로고
    • Drinking habits as cofactors of risk for alcohol induced liver damage
    • Bellentani S, Saccoccio G, Costa G, Tiribelli C, Manenti F, et al. (1997) Drinking habits as cofactors of risk for alcohol induced liver damage. Gut 41: 845-850.
    • (1997) Gut , vol.41 , pp. 845-850
    • Bellentani, S.1    Saccoccio, G.2    Costa, G.3    Tiribelli, C.4    Manenti, F.5
  • 37
    • 0037221394 scopus 로고    scopus 로고
    • Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
    • Ruhl CE, Everhart JE (2003) Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. GASTROENTEROLOGY-BALTIMORE THEN PHILADELPHIA- 124: 71-79.
    • (2003) Gastroenterology-Baltimore then Philadelphia , vol.124 , pp. 71-79
    • Ruhl, C.E.1    Everhart, J.E.2
  • 38
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 39
    • 14844340783 scopus 로고    scopus 로고
    • Unexplained elevations in alanine aminotransferase in individuals with the metabolic syndrome: Results from the third National Health and Nutrition Survey (NHANES III)
    • Liangpunsakul S, Chalasani N (2005) Unexplained elevations in alanine aminotransferase in individuals with the metabolic syndrome: results from the third National Health and Nutrition Survey (NHANES III). The American journal of the medical sciences 329: 111-116.
    • (2005) The American Journal of the Medical Sciences , vol.329 , pp. 111-116
    • Liangpunsakul, S.1    Chalasani, N.2
  • 40
    • 0021075388 scopus 로고
    • Sex difference in chronic hepatitis B virus infection: An appraisal based on the status of hepatitis B e antigen and antibody
    • Chu CM, Liaw YF, Sheen I, Lin DY, Huang MJ (1983) Sex difference in chronic hepatitis B virus infection: an appraisal based on the status of hepatitis B e antigen and antibody. Hepatology 3: 947-950.
    • (1983) Hepatology , vol.3 , pp. 947-950
    • Chu, C.M.1    Liaw, Y.F.2    Sheen, I.3    Lin, D.Y.4    Huang, M.J.5
  • 41
    • 0030800166 scopus 로고    scopus 로고
    • Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: A French survey of 6,664 patients
    • Roudot-Thoraval F, Bastie A, Pawlotsky J, Dhumeaux D (1997) Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: A French survey of 6,664 patients. Hepatology 26: 485-490.
    • (1997) Hepatology , vol.26 , pp. 485-490
    • Roudot-Thoraval, F.1    Bastie, A.2    Pawlotsky, J.3    Dhumeaux, D.4
  • 43
    • 0034802218 scopus 로고    scopus 로고
    • Estimating progression to cirrhosis in chronic hepatitis C virus infection
    • Freeman AJ, Dore GJ, Law MG, Thorpe M, Von Overbeck J, et al. (2001) Estimating progression to cirrhosis in chronic hepatitis C virus infection. Hepatology 34: 809-816.
    • (2001) Hepatology , vol.34 , pp. 809-816
    • Freeman, A.J.1    Dore, G.J.2    Law, M.G.3    Thorpe, M.4    Von Overbeck, J.5
  • 45
    • 52949142682 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome
    • Kim CH, YOUNOSSI ZM (2008) Nonalcoholic fatty liver disease: a manifestation of the metabolic syndrome. Cleveland Clinic Journal of Medicine 75: 721-728.
    • (2008) Cleveland Clinic Journal of Medicine , vol.75 , pp. 721-728
    • Kim, C.H.1    Younossi, Z.M.2
  • 46
    • 84870661966 scopus 로고    scopus 로고
    • Combinative analysis of factors influence serum alanine aminotransferase activity in adult male population from southern China
    • Liu Z, Hu Y, Yang X, Tan A, Gao Y, et al. (2012) Combinative analysis of factors influence serum alanine aminotransferase activity in adult male population from southern China. Clinical Biochemistry.
    • (2012) Clinical Biochemistry
    • Liu, Z.1    Hu, Y.2    Yang, X.3    Tan, A.4    Gao, Y.5
  • 47
    • 42249103062 scopus 로고    scopus 로고
    • Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease
    • Kim W, Flamm SL, Di Bisceglie AM, Bodenheimer HC (2008) Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease. Hepatology 47: 1363-1370.
    • (2008) Hepatology , vol.47 , pp. 1363-1370
    • Kim, W.1    Flamm, S.L.2    Di Bisceglie, A.M.3    Bodenheimer, H.C.4
  • 48
    • 20944449901 scopus 로고    scopus 로고
    • Prevalence and etiology of altered liver tests: A population-based survey in a Mediterranean town
    • Pendino GM, Mariano A, Surace P, Caserta CA, Fiorillo MT, et al. (2005) Prevalence and etiology of altered liver tests: A population-based survey in a Mediterranean town. Hepatology 41: 1151-1159.
    • (2005) Hepatology , vol.41 , pp. 1151-1159
    • Pendino, G.M.1    Mariano, A.2    Surace, P.3    Caserta, C.A.4    Fiorillo, M.T.5
  • 49
    • 34547964678 scopus 로고    scopus 로고
    • Prevalence and etiology of elevated serum alanine aminotransferase level in an adult population in Taiwan
    • Chen CH, Huang MH, Yang JC, Nien CK, Yang CC, et al. (2007) Prevalence and etiology of elevated serum alanine aminotransferase level in an adult population in Taiwan. Journal of gastroenterology and hepatology 22: 1482-1489.
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , pp. 1482-1489
    • Chen, C.H.1    Huang, M.H.2    Yang, J.C.3    Nien, C.K.4    Yang, C.C.5
  • 50
    • 54049091645 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Hepatic manifestation of obesity and the metabolic syndrome
    • Boppidi H, Daram SR (2008) Nonalcoholic fatty liver disease: hepatic manifestation of obesity and the metabolic syndrome. Postgraduate medicine 120: E01.
    • (2008) Postgraduate Medicine , vol.120
    • Boppidi, H.1    Daram, S.R.2
  • 51
    • 84891882101 scopus 로고    scopus 로고
    • Gammaic fatty liver disease: Hepatic manifestation of obesity and the metabolic syndrome
    • Liu CF, Zhou WN, Fang NY (2012) Gammaic fatty liver disease: hepatic manifestation of obesity and the metabolic syndrome. Postgraduate medicine 120: E01.
    • (2012) Postgraduate Medicine , vol.120
    • Liu, C.F.1    Zhou, W.N.2    Fang, N.Y.3
  • 53
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R, Horton JD, Cohen JC, et al. (2004) Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 40: 1387-1395.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3    Horton, J.D.4    Cohen, J.C.5
  • 54
    • 33745401989 scopus 로고    scopus 로고
    • Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease
    • Eguchi Y, Eguchi T, Mizuta T, Ide Y, Yasutake T, et al. (2006) Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. Journal of gastroenterology 41: 462-469.
    • (2006) Journal of Gastroenterology , vol.41 , pp. 462-469
    • Eguchi, Y.1    Eguchi, T.2    Mizuta, T.3    Ide, Y.4    Yasutake, T.5
  • 55
    • 34047098736 scopus 로고    scopus 로고
    • Serial Metabolic Measurements and Conversion to Type 2 Diabetes in the West of Scotland Coronary Prevention Study Specific Elevations in Alanine Aminotransferase and Triglycerides Suggest Hepatic Fat Accumulation as a Potential Contributing Factor
    • Sattar N, McConnachie A, Ford I, Gaw A, Cleland SJ, et al. (2007) Serial Metabolic Measurements and Conversion to Type 2 Diabetes in the West of Scotland Coronary Prevention Study Specific Elevations in Alanine Aminotransferase and Triglycerides Suggest Hepatic Fat Accumulation as a Potential Contributing Factor. Diabetes 56: 984-991.
    • (2007) Diabetes , vol.56 , pp. 984-991
    • Sattar, N.1    McConnachie, A.2    Ford, I.3    Gaw, A.4    Cleland, S.J.5
  • 56
    • 84876490780 scopus 로고    scopus 로고
    • The association of alanine aminotransferase within the normal and mildly elevated range with lipoproteins and apolipoproteins: The Insulin Resistance Atherosclerosis Study
    • Lorenzo C, Hanley A, Rewers M, Haffner S (2013) The association of alanine aminotransferase within the normal and mildly elevated range with lipoproteins and apolipoproteins: the Insulin Resistance Atherosclerosis Study. Diabetologia: 1-12.
    • (2013) Diabetologia , pp. 1-12
    • Lorenzo, C.1    Hanley, A.2    Rewers, M.3    Haffner, S.4
  • 58
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
    • Seppälä-Lindroos A, Vehkavaara S, Häkkinen A-M, Goto T, Westerbacka J, et al. (2002) Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. Journal of Clinical Endocrinology & Metabolism 87: 3023-3028.
    • (2002) Journal of Clinical Endocrinology & Metabolism , vol.87 , pp. 3023-3028
    • Seppälä-Lindroos, A.1    Vehkavaara, S.2    Häkkinen, A.-M.3    Goto, T.4    Westerbacka, J.5
  • 59
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, et al. (2002) High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51: 1889-1895.
    • (2002) Diabetes , vol.51 , pp. 1889-1895
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3    Saremi, A.4    Pratley, R.E.5
  • 60
    • 33644674139 scopus 로고    scopus 로고
    • Gender differences in the metabolic syndrome and their role for cardiovascular disease
    • Regitz-Zagrosek V, Lehmkuhl E, Weickert MO (2006) Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clinical Research in Cardiology 95: 136-147.
    • (2006) Clinical Research in Cardiology , vol.95 , pp. 136-147
    • Regitz-Zagrosek, V.1    Lehmkuhl, E.2    Weickert, M.O.3
  • 62
    • 0346095543 scopus 로고    scopus 로고
    • Girls at five are intrinsically more insulin resistant than boys: The programming hypotheses revisited-The EarlyBird Study (EarlyBird 6)
    • Murphy MJ, Metcalf BS, Voss LD, Jeffery AN, Kirkby J, et al. (2004) Girls at five are intrinsically more insulin resistant than boys: the programming hypotheses revisited-The EarlyBird Study (EarlyBird 6). Pediatrics 113: 82-86.
    • (2004) Pediatrics , vol.113 , pp. 82-86
    • Murphy, M.J.1    Metcalf, B.S.2    Voss, L.D.3    Jeffery, A.N.4    Kirkby, J.5
  • 63
    • 0032860997 scopus 로고    scopus 로고
    • Insulin resistance during puberty: Results from clamp studies in 357 children
    • Moran A, Jacobs DR, Steinberger J, Hong C-P, Prineas R, et al. (1999) Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 48: 2039-2044.
    • (1999) Diabetes , vol.48 , pp. 2039-2044
    • Moran, A.1    Jacobs, D.R.2    Steinberger, J.3    Hong, C.-P.4    Prineas, R.5
  • 66
    • 0043240339 scopus 로고    scopus 로고
    • Prevalence of a metabolic syndrome phenotype in adolescents: Findings from the third National Health and Nutrition Examination Survey, 1988-1994
    • Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH (2003) Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Archives of pediatrics & adolescent medicine 157: 821.
    • (2003) Archives of Pediatrics & Adolescent Medicine , vol.157 , pp. 821
    • Cook, S.1    Weitzman, M.2    Auinger, P.3    Nguyen, M.4    Dietz, W.H.5
  • 68
    • 84860756406 scopus 로고    scopus 로고
    • Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in HumansClinical Perspective
    • Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, et al. (2012) Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in HumansClinical Perspective. Circulation 125: 2222-223.
    • (2012) Circulation , vol.125 , pp. 2222-2223
    • Cheng, S.1    Rhee, E.P.2    Larson, M.G.3    Lewis, G.D.4    McCabe, E.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.