Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels

Journal of Molecular Biology

Volumn 426, Issue 2, 2014, Pages 467-483

  Shaya, David ^a   Findeisen, Felix ^a   Abderemane Ali, Fayal ^b,c,d   Arrigoni, Cristina ^a   Wong, Stephanie ^a   Nurva, Shailika Reddy ^a   Loussouarn, Gildas ^b,c,d   Minor, Daniel L ^a,e,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSERM   (France)

^c CNRS   (France)

^d L INSTITUT DU THORAX   (France)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

electrophysiology; ion binding; voltage gated calcium channel; voltage gated sodium channel; X ray crystallography

Indexed keywords

ION; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BINDING SITE; CALCIUM BINDING; CHANNEL GATING; CHEMICAL STRUCTURE; ELECTROPHYSIOLOGY; EUKARYOTE; ION TRANSPORT; MAMMAL; NECK; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; TAIL; UNITED STATES;

ALKALILIMNICOLA EHRLICHEI; BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; PROKARYOTA;

DDM; EGTA; ELECTROPHYSIOLOGY; ETHYLENE GLYCOL-BIS( 2-AMINOETHYLETHER)-N, N,N′,N′-TETRAACETIC ACID; ION BINDING; PD; PEG; POLYETHYLENE GLYCOL; PORE DOMAIN; VGIC; VOLTAGE-GATED CALCIUM CHANNEL; VOLTAGE-GATED ION CHANNEL; VOLTAGE-GATED SODIUM CHANNEL; VOLTAGE-SENSING DOMAIN; VSD; X-RAY CRYSTALLOGRAPHY; Β-DODECYL MALTOSIDE;

AMINO ACID SEQUENCE; BINDING SITES; CALIFORNIA; CRYSTALLOGRAPHY, X-RAY; ECTOTHIORHODOSPIRACEAE; IONS; LAKES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; VOLTAGE-GATED SODIUM CHANNELS; WATER MICROBIOLOGY;

EID: 84891835113     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.10.010     Document Type: Article

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