Catalysis of Na+ permeation in the bacterial sodium channel NavAb

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 28, 2013, Pages 11331-11336

  Chakrabarti, Nilmadhab ^a   Ing, Christopher ^a,b   Payandeh, Jian ^c,e   Zheng, Ning ^c,d   Catterall, William A ^c   Pomès, Reǵis ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM; SODIUM CHANNEL; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL NAVAB;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ION TRANSPORT; ISOMERIZATION; MEMBRANE ELECTROPHYSIOLOGY; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SIMULATION;

CATALYSIS; ION TRANSPORT; KINETICS; SODIUM; SODIUM CHANNELS;

BACTERIA (MICROORGANISMS);

EID: 84879912778     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309452110     Document Type: Article

References (35)

1. Hille B (2001) Ionic Channels of Excitable Membranes (Sinauer Associates, Sunderland, MA), 3rd Ed.
2. Catterall WA (2000) From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels. Neuron 26(1):13-25.
3. Catterall WA (2012) Voltage-gated sodium channels at 60: Structure, function and pathophysiology. J Physiol 590(Pt 11):2577-2589.
4. Bezanilla F (2008) How membrane proteins sense voltage. Nat Rev Mol Cell Biol 9(4):323-332.
5. George AL, Jr. (2005) Inherited disorders of voltage-gated sodium channels. J Clin Invest 115(8):1990-1999.
6. Catterall WA (2010) Ion channel voltage sensors: Structure, function, and pathophysiology. Neuron 67(6):915-928.
7. + conduction and selectivity. Science 280(5360):69-77.
8. + channel. Nature 423(6935):33-41.
9. Jiang Y, Ruta V, Chen J, Lee A, MacKinnon R (2003) The principle of gating charge movement in a voltage-dependent K+ channel. Nature 423(6935):42-48. (Pubitemid 36569578)
10. Bernèche S, Roux B (2002) The ionization state and the conformation of Glu-71 in the KcsA K(+) channel. Biophys J 82(2):772-780. (Pubitemid 34111218)
11. v1.2: Structural basis of electromechanical coupling. Science 309(5736):903-908.
12. Long SB, Campbell EB, Mackinnon R (2005) Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309(5736):897-903. (Pubitemid 41099919)
13. Payandeh J, Scheuer T, Zheng N, Catterall WA (2011) The crystal structure of a voltage-gated sodium channel. Nature 475(7356):353-358.
14. Terlau H, et al. (1991) Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II. FEBS Lett 293(1-2):93-96.
15. Heinemann SH, Terlau H, Stühmer W, Imoto K, Numa S (1992) Calcium channel characteristics conferred on the sodium channel by single mutations. Nature 356(6368):441-443.
16. + selectivity filter. Nature 414(6859):37-42.
17. Maguire ME, Cowan JA (2002) Magnesium chemistry and biochemistry. Biometals 15(3):203-210. (Pubitemid 34816205)
18. Carnevale V, Treptow W, Klein ML (2011) Sodium ion binding sites and hydration in the lumen of a bacterial ion channel from molecular dynamics simulations. J Phys Chem Lett 2(19):2504-2508.
19. Furini S, Domene C (2012) On conduction in a bacterial sodium channel. PLOS Comput Biol 8(4):e1002476.
20. Corry B, Thomas M (2012) Mechanism of ion permeation and selectivity in a voltage gated sodium channel. J Am Chem Soc 134(3):1840-1846.
21. Qiu H, Shen R, Guo W (2012) Ion solvation and structural stability in a sodium channel investigated by molecular dynamics calculations. Biochim Biophys Acta 1818(11):2529-2535.
22. 2+ selectivity in the bacterial voltage-gated sodium channel NavAb. PeerJ 1:e16.
23. Stock L, Delemotte L, Carnevale V, Treptow W, Klein ML (2013) Conduction in a biological sodium selective channel. J Phys Chem B 117(14):3782-3789.
24. vAb. Biochim Biophys Acta 430(4):1272-1276.
25. Ulmschneider MB, et al. (2013) Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel. Proc Natl Acad Sci USA 110(16):6364-6369.
26. + channel-Fab complex at 2.0 A resolution. Nature 414(6859):43-48.
27. Roux B, et al. (2011) Ion selectivity in channels and transporters. J Gen Physiol 137(5):415-426.
28. Andersen OS (2011) Perspectives on: Ion selectivity. J Gen Physiol 137(5):393-395.
29. Hess B, Kutzner C, van der Spoel D, Lindhal E (2008) GROMACS 4: Algorithms for highly ef ficient, load-balanced, and scalabale molecular simulations. J Chem Theory Comput 4(3):435-447.
30. Jorgensen WL, Maxwell DS, Tirado-Rives J (1996) Development and testing of the OPLS all-atom force field onthe conformaional energetics and properties of organic liquids. J Am Chem Soc 118(45):11225-11236. (Pubitemid 26399746)
31. Kaminski GA, Friesner RA, Tirado-Rives J, Jorgensen WL (2001) Evaluation and reparametrization of the OPLS-AA force field for proteins via comparison with accurate quantum chemical calculations on peptides. J Phys Chem B 105(28):6474-6487. (Pubitemid 35339015)
32. Jorgensen W, Chandrasekhar J, Madura J, Impey R, Klein M (1983) Comparison of simple potential functions for simulating liquid water. J Chem Phys 79(2):926-935.
33. Berger O, Edholm O, Jähnig F (1997) Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys J 72(5):2002-2013. (Pubitemid 27184429)
34. Chakrabarti N, Neale C, Payandeh J, Pai EF, Pomès R (2010) An iris-like mechanism of pore dilation in the CorA magnesium transport system. Biophys J 98(5):784-792.
35. MacKerell AD, Jr., et al. (1998) All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B 102(18):3586-3616.