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Volumn 92, Issue 1, 2014, Pages 90-98

Colitogenic effector T cells: Roles of gut-homing integrin, gut antigen specificity and γδ T cells

Author keywords

4 7 integrin; CD4 T cells; Colitis; Gut antigens; IBD

Indexed keywords

ALPHA4BETA7 INTEGRIN; CD11B ANTIGEN; GAMMA INTERFERON; HERMES ANTIGEN; INTEGRIN; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84891833102     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.70     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 0028519015 scopus 로고
    • Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
    • Powrie F, Leach MW, Mauze S, Menon S, Caddle LB, Coffman RL. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994; 1: 553-562.
    • (1994) Immunity , vol.1 , pp. 553-562
    • Powrie, F.1    Leach, M.W.2    Mauze, S.3    Menon, S.4    Caddle, L.B.5    Coffman, R.L.6
  • 3
    • 79954999095 scopus 로고    scopus 로고
    • Cutting edge: Generation of colitogenic Th17 CD4 T cells is enhanced by IL-17+ gammadelta T cells
    • Do JS, Visperas A, Dong C, Baldwin WM 3rd, Min B. Cutting edge: Generation of colitogenic Th17 CD4 T cells is enhanced by IL-17+ gammadelta T cells. J Immunol 2011; 186: 4546-4550.
    • (2011) J Immunol , vol.186 , pp. 4546-4550
    • Do, J.S.1    Visperas, A.2    Dong, C.3    Baldwin III, W.M.4    Min, B.5
  • 4
    • 20144363585 scopus 로고    scopus 로고
    • Recent immune status determines the source of antigens that drive homeostatic T cell expansion
    • Kieper WC, Troy A, Burghardt JT, Ramsey C, Lee JY, Jiang HQ et al. Recent immune status determines the source of antigens that drive homeostatic T cell expansion. J Immunol 2005; 174: 3158-3163.
    • (2005) J Immunol , vol.174 , pp. 3158-3163
    • Kieper, W.C.1    Troy, A.2    Burghardt, J.T.3    Ramsey, C.4    Lee, J.Y.5    Jiang, H.Q.6
  • 5
    • 33846844985 scopus 로고    scopus 로고
    • Generation of gut-homing T cells and their localization to the small intestinal mucosa
    • Johansson-Lindbom B, Agace WW. Generation of gut-homing T cells and their localization to the small intestinal mucosa. Immunol Rev 2007; 215: 226-242.
    • (2007) Immunol Rev , vol.215 , pp. 226-242
    • Johansson-Lindbom, B.1    Agace, W.W.2
  • 6
    • 0141449950 scopus 로고    scopus 로고
    • Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): Requirement for GALT dendritic cells and adjuvant
    • Johansson-Lindbom B, Svensson M, Wurbel MA, Malissen B, Marquez G, Agace W. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 2003; 198: 963-969.
    • (2003) J Exp Med , vol.198 , pp. 963-969
    • Johansson-Lindbom, B.1    Svensson, M.2    Wurbel, M.A.3    Malissen, B.4    Marquez, G.5    Agace, W.6
  • 8
    • 39649112192 scopus 로고    scopus 로고
    • Homing imprinting and immunomodulation in the gut: Role of dendritic cells and retinoids
    • Mora JR. Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids. Inflamm Bowel Dis 2008; 14: 275-289.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 275-289
    • Mora, J.R.1
  • 10
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, Hall J, Sun CM, Belkaid Y et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007; 204: 1757-1764.
    • (2007) J Exp Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6
  • 11
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6 J Clin Invest 2006; 116: 1310-1316.
    • (2006) J Clin Invest , vol.116 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3    Poulet, F.4    McClanahan, T.5    McKenzie, B.6
  • 12
    • 34250026960 scopus 로고    scopus 로고
    • Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
    • Elson CO, Cong Y, Weaver CT, Schoeb TR, McClanahan TK, Fick RB et al. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 2007; 132: 2359-2370.
    • (2007) Gastroenterology , vol.132 , pp. 2359-2370
    • Elson, C.O.1    Cong, Y.2    Weaver, C.T.3    Schoeb, T.R.4    McClanahan, T.K.5    Fick, R.B.6
  • 13
    • 80755180843 scopus 로고    scopus 로고
    • Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation
    • Cai Y, Shen X, Ding C, Qi C, Li K, Li X et al. Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation. Immunity 2011; 35: 596-610.
    • (2011) Immunity , vol.35 , pp. 596-610
    • Cai, Y.1    Shen, X.2    Ding, C.3    Qi, C.4    Li, K.5    Li, X.6
  • 14
    • 84858644639 scopus 로고    scopus 로고
    • Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive gamma/delta T cells in patients with active ankylosing spondylitis
    • Kenna TJ, Davidson SI, Duan R, Bradbury LA, McFarlane J, Smith M et al. Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive gamma/delta T cells in patients with active ankylosing spondylitis. Arthritis Rheum 2012; 64: 1420-1429.
    • (2012) Arthritis Rheum , vol.64 , pp. 1420-1429
    • Kenna, T.J.1    Davidson, S.I.2    Duan, R.3    Bradbury, L.A.4    McFarlane, J.5    Smith, M.6
  • 15
    • 77957021670 scopus 로고    scopus 로고
    • Gammadelta T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism
    • Petermann F, Rothhammer V, Claussen MC, Haas JD, Blanco LR, Heink S et al. gammadelta T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. Immunity 2010; 33: 351-363.
    • (2010) Immunity , vol.33 , pp. 351-363
    • Petermann, F.1    Rothhammer, V.2    Claussen, M.C.3    Haas, J.D.4    Blanco, L.R.5    Heink, S.6
  • 16
    • 84865718141 scopus 로고    scopus 로고
    • IL-17-producing gammadelta T cells and innate lymphoid cells
    • Sutton CE, Mielke LA, Mills KH. IL-17-producing gammadelta T cells and innate lymphoid cells. Eur J Immunol 2012; 42: 2221-2231.
    • (2012) Eur J Immunol , vol.42 , pp. 2221-2231
    • Sutton, C.E.1    Mielke, L.A.2    Mills, K.H.3
  • 17
    • 20444469332 scopus 로고    scopus 로고
    • Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
    • Feagan BG, Greenberg GR, Wild G, Fedorak RN, Pare P, McDonald JW et al. Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. N Engl J Med 2005; 352: 2499-2507.
    • (2005) N Engl J Med , vol.352 , pp. 2499-2507
    • Feagan, B.G.1    Greenberg, G.R.2    Wild, G.3    Fedorak, R.N.4    Pare, P.5    McDonald, J.W.6
  • 18
    • 32644449066 scopus 로고    scopus 로고
    • Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine
    • Waldman E, Lu SX, Hubbard VM, Kochman AA, Eng JM, Terwey TH et al. Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine. Blood 2006; 107: 1703-1711.
    • (2006) Blood , vol.107 , pp. 1703-1711
    • Waldman, E.1    Lu, S.X.2    Hubbard, V.M.3    Kochman, A.A.4    Eng, J.M.5    Terwey, T.H.6
  • 20
    • 84878077227 scopus 로고    scopus 로고
    • Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells
    • Kawabe T, Sun SL, Fujita T, Yamaki S, Asao A, Takahashi T et al. Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells. J Immunol 2013; 190: 5788-5798.
    • (2013) J Immunol , vol.190 , pp. 5788-5798
    • Kawabe, T.1    Sun, S.L.2    Fujita, T.3    Yamaki, S.4    Asao, A.5    Takahashi, T.6
  • 21
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004; 427: 355-360.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1    Lo, C.G.2    Cinamon, G.3    Lesneski, M.J.4    Xu, Y.5    Brinkmann, V.6
  • 22
    • 83955163603 scopus 로고    scopus 로고
    • Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions
    • Do JS, Foucras G, Kamada N, Schenk AF, Shaw M, Nunez G et al. Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions. Cell Immunol 2012; 272: 117-123.
    • (2012) Cell Immunol , vol.272 , pp. 117-123
    • Do, J.S.1    Foucras, G.2    Kamada, N.3    Schenk, A.F.4    Shaw, M.5    Nunez, G.6
  • 23
    • 79952677649 scopus 로고    scopus 로고
    • Retinoic acid, immunity, and inflammation
    • Kim CH. Retinoic acid, immunity, and inflammation. Vitam Horm 2011; 86: 83-101.
    • (2011) Vitam Horm , vol.86 , pp. 83-101
    • Kim, C.H.1
  • 24
    • 26844538936 scopus 로고    scopus 로고
    • Functional specialization of gut CD103+ dendritic cells in the regulation of tissueselective T cell homing
    • Johansson-Lindbom B, Svensson M, Pabst O, Palmqvist C, Marquez G, Forster R et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissueselective T cell homing. J Exp Med 2005; 202: 1063-1073.
    • (2005) J Exp Med , vol.202 , pp. 1063-1073
    • Johansson-Lindbom, B.1    Svensson, M.2    Pabst, O.3    Palmqvist, C.4    Marquez, G.5    Forster, R.6
  • 26
    • 0027237424 scopus 로고
    • Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
    • Berlin C, Berg EL, Briskin MJ, Andrew DP, Kilshaw PJ, Holzmann B et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993; 74: 185-195.
    • (1993) Cell , vol.74 , pp. 185-195
    • Berlin, C.1    Berg, E.L.2    Briskin, M.J.3    Andrew, D.P.4    Kilshaw, P.J.5    Holzmann, B.6
  • 27
    • 0031255003 scopus 로고    scopus 로고
    • CD4+ T-cells in the regulation of inflammatory responses in the intestine
    • Powrie F, Mauze S, Coffman RL. CD4+ T-cells in the regulation of inflammatory responses in the intestine. Res Immunol 1997; 148: 576-581.
    • (1997) Res Immunol , vol.148 , pp. 576-581
    • Powrie, F.1    Mauze, S.2    Coffman, R.L.3
  • 28
    • 0035133290 scopus 로고    scopus 로고
    • Enteric bacterial antigens activate CD4(+) T cells from scid mice with inflammatory bowel disease
    • Brimnes J, Reimann J, Nissen M, Claesson M. Enteric bacterial antigens activate CD4(+) T cells from scid mice with inflammatory bowel disease. Eur J Immunol 2001; 31: 23-31.
    • (2001) Eur J Immunol , vol.31 , pp. 23-31
    • Brimnes, J.1    Reimann, J.2    Nissen, M.3    Claesson, M.4
  • 29
    • 68649126866 scopus 로고    scopus 로고
    • Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
    • Martin B, Hirota K, Cua DJ, Stockinger B, Veldhoen M. Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity 2009; 31: 321-330.
    • (2009) Immunity , vol.31 , pp. 321-330
    • Martin, B.1    Hirota, K.2    Cua, D.J.3    Stockinger, B.4    Veldhoen, M.5
  • 30
    • 73249144785 scopus 로고    scopus 로고
    • CCR6 and NK1.1 distinguish between IL-17A and IFN-gamma-producing gammadelta effector T cells
    • Haas JD, Gonzalez FH, Schmitz S, Chennupati V, Fohse L, Kremmer E et al. CCR6 and NK1.1 distinguish between IL-17A and IFN-gamma-producing gammadelta effector T cells. Eur J Immunol 2009; 39: 3488-3497.
    • (2009) Eur J Immunol , vol.39 , pp. 3488-3497
    • Haas, J.D.1    Gonzalez, F.H.2    Schmitz, S.3    Chennupati, V.4    Fohse, L.5    Kremmer, E.6
  • 31
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
    • Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009; 31: 331-341.
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5    Mills, K.H.6
  • 32
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation
    • Persson EK, Uronen-Hansson H, Semmrich M, Rivollier A, Hagerbrand K, Marsal J et al. IRF4 Transcription-Factor-Dependent CD103(+)CD11b(+) Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation. Immunity 2013; 38: 958-969.
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1    Uronen-Hansson, H.2    Semmrich, M.3    Rivollier, A.4    Hagerbrand, K.5    Marsal, J.6
  • 33
    • 84875489998 scopus 로고    scopus 로고
    • Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation
    • Farache J, Koren I, Milo I, Gurevich I, Kim KW, Zigmond E et al. Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity 2013; 38: 581-595.
    • (2013) Immunity , vol.38 , pp. 581-595
    • Farache, J.1    Koren, I.2    Milo, I.3    Gurevich, I.4    Kim, K.W.5    Zigmond, E.6
  • 34
    • 0034162570 scopus 로고    scopus 로고
    • Systemic activation and antigen-driven oligoclonal expansion of T cells in a mouse model of colitis
    • Matsuda JL, Gapin L, Sydora BC, Byrne F, Binder S, Kronenberg M et al. Systemic activation and antigen-driven oligoclonal expansion of T cells in a mouse model of colitis. J Immunol 2000; 164: 2797-2806.
    • (2000) J Immunol , vol.164 , pp. 2797-2806
    • Matsuda, J.L.1    Gapin, L.2    Sydora, B.C.3    Byrne, F.4    Binder, S.5    Kronenberg, M.6
  • 35
    • 0032536827 scopus 로고    scopus 로고
    • CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/ HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
    • Cong Y, Brandwein SL, McCabe RP, Lazenby A, Birkenmeier EH, Sundberg JP et al. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/ HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med 1998; 187: 855-864.
    • (1998) J Exp Med , vol.187 , pp. 855-864
    • Cong, Y.1    Brandwein, S.L.2    McCabe, R.P.3    Lazenby, A.4    Birkenmeier, E.H.5    Sundberg, J.P.6
  • 36
    • 84864336883 scopus 로고    scopus 로고
    • Enhancement of dendritic cell activation via CD40 ligand-expressing gammadelta T cells is responsible for protective immunity to Plasmodium parasites
    • Inoue S, Niikura M, Takeo S, Mineo S, Kawakami Y, Uchida A et al. Enhancement of dendritic cell activation via CD40 ligand-expressing gammadelta T cells is responsible for protective immunity to Plasmodium parasites. Proc Natl Acad Sci USA 2012; 109: 12129-12134.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 12129-12134
    • Inoue, S.1    Niikura, M.2    Takeo, S.3    Mineo, S.4    Kawakami, Y.5    Uchida, A.6
  • 37
    • 68649090645 scopus 로고    scopus 로고
    • Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells
    • Awasthi A, Riol-Blanco L, Jager A, Korn T, Pot C, Galileos G et al. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J Immunol 2009; 182: 5904-5908.
    • (2009) J Immunol , vol.182 , pp. 5904-5908
    • Awasthi, A.1    Riol-Blanco, L.2    Jager, A.3    Korn, T.4    Pot, C.5    Galileos, G.6
  • 38
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I et al. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002; 17: 375-387.
    • (2002) Immunity , vol.17 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6
  • 39
    • 1642415714 scopus 로고    scopus 로고
    • Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire
    • Min B, Foucras G, Meier-Schellersheim M, Paul WE. Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. Proc Natl Acad Sci USA 2004; 101: 3874-3879.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3874-3879
    • Min, B.1    Foucras, G.2    Meier-Schellersheim, M.3    Paul, W.E.4
  • 40
    • 65749091607 scopus 로고    scopus 로고
    • A protective function for interleukin 17A in T cell-mediated intestinal inflammation
    • O'Connor W Jr, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y et al. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol 2009; 10: 603-609.
    • (2009) Nat Immunol , vol.10 , pp. 603-609
    • O'Connor Jr., W.1    Kamanaka, M.2    Booth, C.J.3    Town, T.4    Nakae, S.5    Iwakura, Y.6


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