Empirical Bayes estimation of the selected treatment mean for two-stage drop-the-loser trials: A meta-analytic approach

Statistics in Medicine

Volumn 33, Issue 3, 2014, Pages 388-400

  Bowden, Jack ^a   Brannath, Werner ^b   Glimm, Ekkehard ^c  

^a MRC BIOSTATISTICS UNIT   (United Kingdom)

^b UNIVERSITY OF BREMEN   (Germany)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Drop the loser trials; Empirical Bayes estimation; Meta analysis; Temporal coherency

Indexed keywords

ACCURACY; ALGORITHM; ARTICLE; BAYES THEOREM; CALCULATION; LINEAR SYSTEM; MATHEMATICAL MODEL; MAXIMUM LIKELIHOOD ESTIMATE; MEAN SQUARED ERROR; MULTIVARIATE ANALYSIS; PREDICTION; PROBABILITY; SIMULATION; STATISTICAL ANALYSIS; STATISTICAL DISTRIBUTION; STATISTICAL PARAMETERS;

DROP-THE-LOSER TRIALS; EMPIRICAL BAYES ESTIMATION; META-ANALYSIS; TEMPORAL COHERENCY;

BAYES THEOREM; CLINICAL TRIALS AS TOPIC; HUMANS; LIKELIHOOD FUNCTIONS; META-ANALYSIS AS TOPIC; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84891827000     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.5920     Document Type: Article

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