Interval estimation for drop-the-losers designs

Biometrika

Volumn 97, Issue 2, 2010, Pages 405-418

  Wu, Samuel S ^a   Wang, Weizhen ^b   Yang, Mark C K ^c  

^a UNIVERSITY OF FLORIDA   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

^c University of Florida   (United States)

Author keywords

Adaptive design; Clinical trial; Drop the losers design; P value combination; Two stage test

Indexed keywords

EID: 77952813592     PISSN: 00063444     EISSN: 14643510     Source Type: Journal    
DOI: 10.1093/biomet/asq003     Document Type: Article

References (19)

1. BAUER, P. & KÖHNE, K. (1994). Evaluation of experiments with adaptive interim analyses. Biometrics 50, 1029-1041
2. BISCHOFF,W.&MILLER, F. (2005).Adaptive two-stage procedures to find the best treatment in clinical trials. Biometrika 92, 197-212.
3. BRANNATH, W., KÖNIG, F. & BAUER, P. (2006). Estimation in flexible two stage designs. Statist. Med. 25, 3366-3381
4. BRETZ, F., SCHMIDLI, H., KÖNIG, F., RACINE, A. & MAURER, W. (2006). Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general concepts. Biomet. J. 48, 623-634 (Pubitemid 44367905)
5. CHANG, M. (2007). Adaptive design method based on sum of p-values. Statist. Med. 26, 2772-2784
6. CHOW, S. C.&CHANG,M. (2007). Adaptive DesignMethods in Clinical Trials. Boca Raton, FL: Chapman&Hill/CRC.
7. DUNNETT, C. (1955). A multiple comparison procedure for comparing several treatments with a control. J. Am. Statist. Assoc. 50, 1096-1121
8. HSU, J. C. (1996). Multiple Comparisons, Theory and Methods. London: Chapman and Hall.
9. JENNISON, C. & TURNBULL, B. W. (2006). Adaptive and nonadaptive group sequential tests. Biometrika 93, 1-21.
10. KIESER, M. (2005). Discussion of the paper by Sampson and Sill. Biomet. J. 47, 271-273
11. LEHMACHER, W. & WASSMER, G. (1999). Adaptive sample size calculation in group sequential trials. Biometrics 55, 1286-1290
12. LIU, Q., PROSCHAN, M. A. & PLEDGER, G. W. (2002). A unified theory of two-stage adaptive designs. J. Am. Statist. Assoc. 97, 1034-1041
13. SAMPSON, A. R. & SILL, M. W. (2005). Drop-the-losers design: normal case. Biomet. J. 47, 257-268
14. STALLARD, N. & FRIEDE, T. (2008). A group-sequential design for clinical trials with treatment selection. Statist. Med. 27, 620-627
15. STALLARD, N. & TODD, S. (2003). Sequential designs for phase III clinical trials incorporating treatment selection. Statist. Med. 22, 689-703.
16. THALL, P. F., SIMON, R. & ELLENBERG, S. S. (1988). Two-stage selection and testing designs for comparative clinical trials. Biometrika 75, 303-310
17. TSIATIS, A. A.&MEHTA, C. (2003). On the inefficiency of the adaptive design for monitoring clinical trials. Biometrika 90, 367-378
18. WANG, J. (2006). An adaptive two-stage design with treatment selection using the conditional error function approach. Biomet. J. 48, 679-689
19. WILKINSON, D. & MURRAY, J. R. (2001). Galantamine: a randomized double-blind, dose comparison in patients with Alzheimeròs disease. Int. J. Geriatric Psychiat. 16, 852-857