메뉴 건너뛰기




Volumn 42, Issue D1, 2014, Pages

The Transformer database: Biotransformation of xenobiotics

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTITUSSIVE AGENT; CLARITHROMYCIN; CYTOCHROME P450; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DRUG METABOLIZING ENZYME; HYDROCODONE; HYDROMORPHONE; VALPROIC ACID; CARRIER PROTEIN; PRODRUG; XENOBIOTIC AGENT; ENZYME;

EID: 84891812677     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1246     Document Type: Article
Times cited : (62)

References (29)
  • 1
    • 79960599857 scopus 로고    scopus 로고
    • The prevalence of polypharmacy in elderly attenders to an emergency department-A problem with a need for an effective solution
    • Banerjee, A., Mbamalu, D., Ebrahimi, S., Khan, A.A. and Chan, T.F. (2011) The prevalence of polypharmacy in elderly attenders to an emergency department-A problem with a need for an effective solution. Int. J. Emerg. Med., 4, 22.
    • (2011) Int. J. Emerg. Med. , vol.4 , pp. 22
    • Banerjee, A.1    Mbamalu, D.2    Ebrahimi, S.3    Khan, A.A.4    Chan, T.F.5
  • 2
    • 84857824137 scopus 로고    scopus 로고
    • A national census of medicines use: A 24-hour snapshot of Australians aged 50 years and older
    • Morgan, T.K., Williamson, M., Pirotta, M., Stewart, K., Myers, S.P. and Barnes, J. (2012) A national census of medicines use: a 24-hour snapshot of Australians aged 50 years and older. Med. J. Aust., 196, 50-53.
    • (2012) Med. J. Aust. , vol.196 , pp. 50-53
    • Morgan, T.K.1    Williamson, M.2    Pirotta, M.3    Stewart, K.4    Myers, S.P.5    Barnes, J.6
  • 3
    • 84879471833 scopus 로고    scopus 로고
    • Polypharmacy and adverse drug reactions in Japanese elderly taking antihypertensives: A retrospective database study
    • Sato, I. and Akazawa, M. (2013) Polypharmacy and adverse drug reactions in Japanese elderly taking antihypertensives: a retrospective database study. Drug Healthc. Patient Saf., 5, 143-150.
    • (2013) Drug Healthc. Patient Saf. , vol.5 , pp. 143-150
    • Sato, I.1    Akazawa, M.2
  • 4
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou, J., Pomeranz, B.H. and Corey, P.N. (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 279, 1200-1205.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 5
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
    • Phillips, K.A., Veenstra, D.L., Oren, E., Lee, J.K. and Sadee, W. (2001) Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA, 286, 2270-2279.
    • (2001) JAMA , vol.286 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 6
    • 84882887932 scopus 로고    scopus 로고
    • Actual drug-drug interactions in elderly patients discharged from internal medicine clinic: A prospective observational study
    • Marusic, S., Bacic-Vrca, V., Obreli Neto, P.R., Franic, M., Erdeljic, V. and Gojo-Tomic, N. (2013) Actual drug-drug interactions in elderly patients discharged from internal medicine clinic: a prospective observational study. Eur. J. Clin. Pharmacol., 69, 1717-1724.
    • (2013) Eur. J. Clin. Pharmacol. , vol.69 , pp. 1717-1724
    • Marusic, S.1    Bacic-Vrca, V.2    Obreli Neto, P.R.3    Franic, M.4    Erdeljic, V.5    Gojo-Tomic, N.6
  • 7
    • 0034973773 scopus 로고    scopus 로고
    • Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
    • Guengerich, F.P. (2001) Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem. Res. Toxicol., 14, 611-650.
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 611-650
    • Guengerich, F.P.1
  • 8
    • 0025611278 scopus 로고
    • The enzymes of detoxication
    • Jakoby, W.B. and Ziegler, D.M. (1990) The enzymes of detoxication. J. Biol. Chem., 265, 20715-20718.
    • (1990) J. Biol. Chem. , vol.265 , pp. 20715-20718
    • Jakoby, W.B.1    Ziegler, D.M.2
  • 9
    • 84874688353 scopus 로고    scopus 로고
    • The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: What we (need to) know and how we can do so
    • Kell, D.B., Dobson, P.D., Bilsland, E. and Oliver, S.G. (2013) The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so. Drug Discov. Today, 18, 218-239.
    • (2013) Drug Discov. Today , vol.18 , pp. 218-239
    • Kell, D.B.1    Dobson, P.D.2    Bilsland, E.3    Oliver, S.G.4
  • 10
    • 69149087845 scopus 로고    scopus 로고
    • Pharmacogenomics of membrane transporters an overview
    • Yan, Q. (2003) Pharmacogenomics of membrane transporters an overview. Methods Mol. Biol., 227, 1-20.
    • (2003) Methods Mol. Biol. , vol.227 , pp. 1-20
    • Yan, Q.1
  • 11
    • 38349139559 scopus 로고    scopus 로고
    • ABCG transporters: Structure, substrate specificities and physiological roles: A brief overview
    • Velamakanni, S., Wei, S.L., Janvilisri, T. and van Veen, H.W. (2007) ABCG transporters: structure, substrate specificities and physiological roles:a brief overview. J. Bioenerg. Biomembr., 39, 465-471.
    • (2007) J. Bioenerg. Biomembr. , vol.39 , pp. 465-471
    • Velamakanni, S.1    Wei, S.L.2    Janvilisri, T.3    Van Veen, H.W.4
  • 12
    • 65249139907 scopus 로고    scopus 로고
    • Analysis and update of the human solute carrier (SLC) gene superfamily
    • He, L., Vasiliou, K. and Nebert, D.W. (2009) Analysis and update of the human solute carrier (SLC) gene superfamily. Hum. Genomics, 3, 195-206.
    • (2009) Hum. Genomics , vol.3 , pp. 195-206
    • He, L.1    Vasiliou, K.2    Nebert, D.W.3
  • 13
    • 28244485775 scopus 로고    scopus 로고
    • Pharmacogenomics of the human ABC transporter ABCG2: From functional evaluation to drug molecular design
    • Ishikawa, T., Tamura, A., Saito, H., Wakabayashi, K. and Nakagawa, H. (2005) Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design. Naturwissenschaften, 92, 451-463.
    • (2005) Naturwissenschaften , vol.92 , pp. 451-463
    • Ishikawa, T.1    Tamura, A.2    Saito, H.3    Wakabayashi, K.4    Nakagawa, H.5
  • 14
    • 38649120829 scopus 로고    scopus 로고
    • Drugs and their molecular targets: An updated overview
    • Landry, Y. and Gies, J.P. (2008) Drugs and their molecular targets: an updated overview. Fundam. Clin. Pharmacol., 22, 1-18.
    • (2008) Fundam. Clin. Pharmacol. , vol.22 , pp. 1-18
    • Landry, Y.1    Gies, J.P.2
  • 15
    • 0001199533 scopus 로고
    • Chemical aspects of selective toxicity
    • Albert, A. (1958) Chemical aspects of selective toxicity. Nature, 182, 421-422.
    • (1958) Nature , vol.182 , pp. 421-422
    • Albert, A.1
  • 16
    • 0036051551 scopus 로고    scopus 로고
    • Potential cardiac toxicity of H1-antihistamines
    • Yap, Y.G. and Camm, A.J. (2002) Potential cardiac toxicity of H1-antihistamines. Clin. Allergy Immunol., 17, 389-419.
    • (2002) Clin. Allergy Immunol. , vol.17 , pp. 389-419
    • Yap, Y.G.1    Camm, A.J.2
  • 17
    • 0033951038 scopus 로고    scopus 로고
    • Using photolabile ligands in drug discovery and development
    • Dorman, G. and Prestwich, GD. (2000) Using photolabile ligands in drug discovery and development. Trends Biotechnol., 18, 64-77.
    • (2000) Trends Biotechnol. , vol.18 , pp. 64-77
    • Dorman, G.1    Prestwich, G.D.2
  • 18
    • 34247637637 scopus 로고    scopus 로고
    • Beta-aminoketones as prodrugs with pH-controlled activation
    • Simplicio, A.L., Clancy, J.M. and Gilmer, J.F. (2007) Beta-aminoketones as prodrugs with pH-controlled activation. Int. J. Pharm., 336, 208-214.
    • (2007) Int. J. Pharm. , vol.336 , pp. 208-214
    • Simplicio, A.L.1    Clancy, J.M.2    Gilmer, J.F.3
  • 19
    • 55249095031 scopus 로고    scopus 로고
    • Cytochrome P450-activated prodrugs: Targeted drug delivery
    • Huttunen, K.M., Mahonen, N., Raunio, H. and Rautio, J. (2008) Cytochrome P450-activated prodrugs: targeted drug delivery. Curr. Med. Chem., 15, 2346-2365.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 2346-2365
    • Huttunen, K.M.1    Mahonen, N.2    Raunio, H.3    Rautio, J.4
  • 20
    • 0031941292 scopus 로고    scopus 로고
    • Regional 'pro-drug' gene therapy: Intravenous administration of an adenoviral vector expressing the E. Coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma
    • Topf, N., Worgall, S., Hackett, N.R. and Crystal, R.G (1998) Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. Coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma. Gene Ther., 5, 507-513.
    • (1998) Gene Ther. , vol.5 , pp. 507-513
    • Topf, N.1    Worgall, S.2    Hackett, N.R.3    Crystal, R.G.4
  • 21
    • 84873281965 scopus 로고    scopus 로고
    • Cytochrome P450-activated prodrugs
    • Ortiz de Montellano, P.R. (2013) Cytochrome P450-activated prodrugs. Future Med. Chem., 5, 213-228.
    • (2013) Future Med. Chem. , vol.5 , pp. 213-228
    • Ortiz De Montellano, P.R.1
  • 22
    • 34047249492 scopus 로고    scopus 로고
    • Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential toxicity for certain drugs
    • Bressler, R. (2006) Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential toxicity for certain drugs. Geriatrics, 61, 12-18.
    • (2006) Geriatrics , vol.61 , pp. 12-18
    • Bressler, R.1
  • 23
    • 49049100709 scopus 로고    scopus 로고
    • Effect of grapefruit juice in relation to human pharmacokinetic study
    • Uno, T. and Yasui-Furukori, N. (2006) Effect of grapefruit juice in relation to human pharmacokinetic study. Curr. Clin. Pharmacol., 1, 157-161.
    • (2006) Curr. Clin. Pharmacol. , vol.1 , pp. 157-161
    • Uno, T.1    Yasui-Furukori, N.2
  • 24
    • 67849104638 scopus 로고    scopus 로고
    • PubChem: A public information system for analyzing bioactivities of small molecules
    • Wang, Y., Xiao, J., Suzek, T.O., Zhang, J., Wang, J. and Bryant, S.H. (2009) PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res., 37, W623-W633.
    • (2009) Nucleic Acids Res. , vol.37
    • Wang, Y.1    Xiao, J.2    Suzek, T.O.3    Zhang, J.4    Wang, J.5    Bryant, S.H.6
  • 25
    • 85027954420 scopus 로고    scopus 로고
    • The Human Cytochrome P450 (CYP) Allele Nomenclature website: A peer-reviewed database of CYP variants and their associated effects
    • Sim, S.C. and Ingelman-Sundberg, M. (2010) The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects. Hum. Genomics, 4, 278-281.
    • (2010) Hum. Genomics , vol.4 , pp. 278-281
    • Sim, S.C.1    Ingelman-Sundberg, M.2
  • 28
    • 79958142858 scopus 로고    scopus 로고
    • Cobweb: A Java applet for network exploration and visualisation
    • von Eichborn, J., Bourne, P.E. and Preissner, R. (2011) Cobweb: a Java applet for network exploration and visualisation. Bioinformatics, 27, 1725-1726.
    • (2011) Bioinformatics , vol.27 , pp. 1725-1726
    • Von Eichborn, J.1    Bourne, P.E.2    Preissner, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.