-
1
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C et al (2007) Patterns of somatic mutation in human cancer genomes. Nature 446(7132):153-158
-
(2007)
Nature
, vol.446
, Issue.7132
, pp. 153-158
-
-
Greenman, C.1
-
2
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance ED et al (2010) A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463(7278): 191-196
-
(2010)
Nature
, vol.463
, Issue.7278
, pp. 191-196
-
-
Pleasance, E.D.1
-
3
-
-
0023479069
-
The specificity of UV-induced mutations at an endogenous locus in mammalian cells
-
Drobetsky EA, Grosovsky AJ, Glickman BW (1987) The specificity of UV-induced mutations at an endogenous locus in mammalian cells. Proc Natl Acad Sci U S A 84(24): 9103-9107
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, Issue.24
, pp. 9103-9107
-
-
Drobetsky, E.A.1
Grosovsky, A.J.2
Glickman, B.W.3
-
4
-
-
84861427327
-
Melanoma genome sequencing reveals frequent PREX2 mutations
-
Berger MF et al (2012) Melanoma genome sequencing reveals frequent PREX2 mutations. Nature 485(7399):502-506
-
(2012)
Nature
, vol.485
, Issue.7399
, pp. 502-506
-
-
Berger, M.F.1
-
5
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin JA et al (2005) Distinct sets of genetic alterations in melanoma. N Engl J Med 353(20):2135-2147
-
(2005)
N Engl J Med
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
-
6
-
-
84863393606
-
Whole genome sequencing of matched primary and metastatic acral melanomas
-
Turajlic S et al (2012) Whole genome sequencing of matched primary and metastatic acral melanomas. Genome Res 22(2):196-207
-
(2012)
Genome Res
, vol.22
, Issue.2
, pp. 196-207
-
-
Turajlic, S.1
-
7
-
-
84862777896
-
Delving into somatic variation in sporadic melanoma
-
Walia V et al (2012) Delving into somatic variation in sporadic melanoma. Pigment Cell Melanoma Res 25(2):155-170
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, Issue.2
, pp. 155-170
-
-
Walia, V.1
-
8
-
-
70349556805
-
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
-
Prickett TD et al (2009) Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet 41(10):1127-1132
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1127-1132
-
-
Prickett, T.D.1
-
9
-
-
69949162760
-
Gefi tinib or carboplatinpaclitaxel in pulmonary adenocarcinoma
-
Mok TS et al (2009) Gefi tinib or carboplatinpaclitaxel in pulmonary adenocarcinoma. N Engl J Med 361(10):947-957
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
-
10
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R et al (2009) Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 361(10):958-967
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 958-967
-
-
Rosell, R.1
-
11
-
-
57749106582
-
Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma
-
Solomon DA et al (2008) Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma. Cancer Res 68(24):10300-10306
-
(2008)
Cancer Res
, vol.68
, Issue.24
, pp. 10300-10306
-
-
Solomon, D.A.1
-
12
-
-
67349149403
-
Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma
-
Palavalli LH et al (2009) Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nat Genet 41(5):518-520
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 518-520
-
-
Palavalli, L.H.1
-
13
-
-
78649670618
-
Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma
-
Wei X et al (2010) Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res 8(11):1513-1525
-
(2010)
Mol Cancer Res
, vol.8
, Issue.11
, pp. 1513-1525
-
-
Wei, X.1
-
14
-
-
79957594872
-
Analysis of the disintegrinmetalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma
-
Wei X et al (2011) Analysis of the disintegrinmetalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma. Hum Mutat 32(6):E2148-E2175
-
(2011)
Hum Mutat
, vol.32
, Issue.6
-
-
Wei, X.1
-
15
-
-
80054997116
-
Exon capture analysis of G protein-coupled receptors identifi es activating mutations in GRM3 in melanoma
-
Prickett TD et al (2011) Exon capture analysis of G protein-coupled receptors identifi es activating mutations in GRM3 in melanoma. Nat Genet 43(11):1119-1126
-
(2011)
Nat Genet
, vol.43
, Issue.11
, pp. 1119-1126
-
-
Prickett, T.D.1
-
16
-
-
84865069757
-
Molecular pathways: Dysregulated glutamatergic signaling pathways in cancer
-
Prickett TD, Samuels Y (2012) Molecular pathways: Dysregulated glutamatergic signaling pathways in cancer. Clin Cancer Res 18(16):4240-4246
-
(2012)
Clin Cancer Res
, vol.18
, Issue.16
, pp. 4240-4246
-
-
Prickett, T.D.1
Samuels, Y.2
-
17
-
-
85027946522
-
Exome sequencing identifi es GRIN2A as frequently mutated in melanoma
-
Wei X et al (2011) Exome sequencing identifi es GRIN2A as frequently mutated in melanoma. Nat Genet 43(5):442-446
-
(2011)
Nat Genet
, vol.43
, Issue.5
, pp. 442-446
-
-
Wei, X.1
-
18
-
-
33745912772
-
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia
-
Hahn CG et al (2006) Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med 12(7):824-828
-
(2006)
Nat Med
, vol.12
, Issue.7
, pp. 824-828
-
-
Hahn, C.G.1
-
19
-
-
0034724391
-
The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses
-
Garcia RA, Vasudevan K, Buonanno A (2000) The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses. Proc Natl Acad Sci U S A 97(7):3596-3601
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.7
, pp. 3596-3601
-
-
Garcia, R.A.1
Vasudevan, K.2
Buonanno, A.3
-
20
-
-
77953738214
-
In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93
-
Delint-Ramirez I et al (2010) In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93. J Neurosci 30(24):8162-8170
-
(2010)
J Neurosci 30
, vol.24
, pp. 8162-8170
-
-
Delint-Ramirez, I.1
-
21
-
-
0037343943
-
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells
-
D'Onofrio M et al (2003) Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells. J Neurochem 84(6):1288-1295
-
(2003)
J Neurochem
, vol.84
, Issue.6
, pp. 1288-1295
-
-
D'Onofrio, M.1
-
22
-
-
33947213963
-
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma
-
Namkoong J et al (2007) Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma. Cancer Res 67(5): 2298-2305
-
(2007)
Cancer Res
, vol.67
, Issue.5
, pp. 2298-2305
-
-
Namkoong, J.1
-
23
-
-
66649107219
-
A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma
-
Yip D et al (2009) A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma. Clin Cancer Res 15(11):3896-3902
-
(2009)
Clin Cancer Res
, vol.15
, Issue.11
, pp. 3896-3902
-
-
Yip, D.1
-
24
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood LD et al (2007) The genomic landscapes of human breast and colorectal cancers. Science 318(5853):1108-1113
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
-
25
-
-
69949170092
-
Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a
-
Fine B et al (2009) Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science 325(5945):1261-1265
-
(2009)
Science
, vol.325
, Issue.5945
, pp. 1261-1265
-
-
Fine, B.1
-
26
-
-
84864042630
-
BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma
-
Colombino M et al (2012) BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma. J Clin Oncol 30(20):2522-2529
-
(2012)
J Clin Oncol
, vol.30
, Issue.20
, pp. 2522-2529
-
-
Colombino, M.1
-
27
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB et al (2011) Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364(26): 2507-2516
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.B.1
-
28
-
-
84863673204
-
Improved survival with MEK inhibition in BRAF-mutated melanoma
-
Flaherty KT et al (2012) Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med 367(2):107-114
-
(2012)
N Engl J Med
, vol.367
, Issue.2
, pp. 107-114
-
-
Flaherty, K.T.1
-
29
-
-
79960708519
-
Phase II, open-label, singlearm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplifi cation
-
Guo J et al (2011) Phase II, open-label, singlearm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplifi cation. J Clin Oncol 29(21): 2904-2909
-
(2011)
J Clin Oncol
, vol.29
, Issue.21
, pp. 2904-2909
-
-
Guo, J.1
-
30
-
-
79952108510
-
Oncogenic mutations of PIK3CA in human cancers
-
Samuels Y, Waldman T (2010) Oncogenic mutations of PIK3CA in human cancers. Curr Top Microbiol Immunol 347:21-41
-
(2010)
Curr Top Microbiol Immunol
, vol.347
, pp. 21-41
-
-
Samuels, Y.1
Waldman, T.2
-
31
-
-
77954725848
-
PIKing the right patient
-
Turke AB, Engelman JA (2010) PIKing the right patient. Clin Cancer Res 16(14):3523-3525
-
(2010)
Clin Cancer Res
, vol.16
, Issue.14
, pp. 3523-3525
-
-
Turke, A.B.1
Engelman, J.A.2
-
32
-
-
84861893379
-
A highthroughput panel for identifying clinically relevant mutation profi les in melanoma
-
Dutton-Regester K et al (2012) A highthroughput panel for identifying clinically relevant mutation profi les in melanoma. Mol Cancer Ther 11(4):888-897
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.4
, pp. 888-897
-
-
Dutton-Regester, K.1
-
33
-
-
80051625929
-
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
-
Wagle N et al (2011) Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. J Clin Oncol 29(22): 3085-3096
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3085-3096
-
-
Wagle, N.1
-
34
-
-
77952512375
-
Screening for EGFR mutations in lung cancer
-
Molina-Vila MA et al (2009) Screening for EGFR mutations in lung cancer. Discov Med 8(43):181-184
-
(2009)
Discov Med
, vol.8
, Issue.43
, pp. 181-184
-
-
Molina-Vila, M.A.1
-
35
-
-
77953589767
-
A growing family: Adding mutated Erbb4 as a novel cancer target
-
Rudloff U, Samuels Y (2010) A growing family: Adding mutated Erbb4 as a novel cancer target. Cell Cycle 9(8):1487-1503
-
(2010)
Cell Cycle
, vol.9
, Issue.8
, pp. 1487-1503
-
-
Rudloff, U.1
Samuels, Y.2
-
36
-
-
18644370411
-
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha
-
Garrett TP et al (2002) Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 110(6): 763-773
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 763-773
-
-
Garrett, T.P.1
-
37
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
Ogiso H et al (2002) Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 110(6): 775-787
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 775-787
-
-
Ogiso, H.1
|