Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis

Retrovirology

Volumn 11, Issue 1, 2014, Pages

  Koppensteiner, Herwig ^a,b   Höhne, Kristin ^a,b   Gondim, Marcos V ^a   Gobert, Francois Xavier ^c   Widder, Miriam ^b,f   Gundlach, Swantje ^b   Heigele, Anke ^d   Kirchhoff, Frank ^d   Winkler, Michael ^e   Benaroch, Philippe ^c   Schindler, Michael ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c PSL RESEARCH UNIVERSITY   (France)

^d UNIVERSITY HOSPITAL ULM   (Germany)

^e GERMAN PRIMATE CENTER   (Germany)

^f MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

AIDS; HIV; Iron homeostasis; Lentiviral replication; Macrophages; Nef; SIV

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN 2; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CELL SURFACE PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; INHIBITION KINETICS; INTERNALIZATION; IRON STORAGE; IRON TRANSPORT; MACROPHAGE; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MOTIF; SIMIAN IMMUNODEFICIENCY VIRUS; UPREGULATION; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; ENDOCYTOSIS; GENE PRODUCTS, NEF; HAPLORHINI; IRON; RECEPTORS, TRANSFERRIN; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSFERRIN;

EID: 84891796475     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-11-1     Document Type: Article

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