Evaluation of in silico, in vitro α-amylase inhibition potential and antidiabetic activity of Pterospermum acerifolium bark

Pharmaceutical Biology

Volumn 52, Issue 2, 2014, Pages 199-207

  Rathinavelusamy, Paramaguru ^a   Mazumder, Papiya Mitra ^a   Sasmal, Dinakar ^a   Jayaprakash, Venkatesan ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY   (India)

Author keywords

3OLE; Autodock; Oxidative stress; Streptozotocin nicotinamide; Type II diabetes

Indexed keywords

ACETIC ACID ETHYL ESTER; ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ALPHA AMYLASE PANCREAS ISOENZYME; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUCOSE; GLUTATHIONE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; PTEROSPERMUM ACERIFOLIUM EXTRACT; SITOSTEROL; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BARK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; MALE; MALVACEAE; MOLECULAR INTERACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PTEROSPERMUM ACERIFOLIUM; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; COMPUTER SIMULATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN BONDING; HYPOGLYCEMIC AGENTS; MALE; NIACINAMIDE; PANCREATIC ALPHA-AMYLASES; PLANT BARK; PLANT EXTRACTS; RATS; RATS, WISTAR; SITOSTEROLS; SOFTWARE; STERCULIACEAE; STREPTOZOCIN; TOXICITY TESTS, ACUTE;

EID: 84891786739     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.823551     Document Type: Article

References (30)

1. Aebi H. (1994). Catalase in vivo methods. Enzymology 105:121-6.
2. Ali H, Houghton PJ, Soumyanath A. (2006). a-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol 107: 449-55.
3. Ananda Prabu K, Kumarappan CT, Christudas S, Kalaichelvan VK. (2012). Effect of Biophytum sensitivum on streptozotocin and nicotinamide induced diabetic rats. Asian Pacific J Trop Biomed 2: 31-5.
4. Aylin S, Sereften A, Cemal C, et al. (2007). Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits. J Ethnopharmacol 110:498-503.
5. Chance B, Greenstein DS, Roughton RJW. (1952). The mechanism of catalase action steady state analysis. Arch Biochem Biophys 37: 301-39.
6. Cheng D. (2005). Prevalence, predisposition and prevention of type II diabetes. Nutr Metab 18:2-29.
7. Chopra RN, Nayar SL, Chopra IC. (1956). Glossary of Indian Medicinal Plants. Council of Scientific & Industrial Research, New Delhi, India. p. 116.
8. Dixit P, Khan MP, Swarnkar G, et al. (2011). Osteogenic constituents from Pterospermum acerifolium Willd. flowers. Bioorg Med Chem Lett 21:4617-21.
9. Gandhi GR, Ignachimuthu S, Paulraj MG. (2012). Hypoglycemic and b-cells regenerative effects of Aegle marmelos (L.) Corr. bark extract in streptozotocin-induced diabetic rats. Food Chem Toxicol 50: 1667-74.
10. Gupta R, Sharma AK, Dobhal MP, et al. (2011). Antidiabetic effect and antioxidant potential of b-sitosterol in streptozotocin-induced experimental hyperglycemia. J Diabetes 3:29-37.
11. King H, Aubert RE, Herman WH. (1998). Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections. Diabetes Care 21:1414-31.
12. Kirtikar KR, Basu BD. (1935). Indian medical plants. J Pharm Res 2: 785-8.
13. Masella R, Vari R, D'Archivio M, et al. (2004). Extra virgin olive oil biophenols inhibit cell mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes. J Nutr 134: 785-91.
14. Mazumder PM, Sasmal D, Ghosh AR, Paramaguru R. (2011). Evaluation of antihyperlipidemic and antioxidant activity of Pterospermum acerifolium (L.) Willd. Pharmacol Online 3:128-46.
15. McCord JM, Keele BB, Fridovich I. (1976). An enzyme based theory of obligate anaerobiosis, the physiological functions of superoxide dismutase. Proc Natl Acad Sci USA 68:1024-7.
16. Misar A, Mujumdar AM, Ruikar A, Deshpande NR. (2010). Quantification of b-sitosterol from barks of three Acacia species by HPTLC. J Pharm Res 3:2595-6.
17. Misra HP, Fridovich I. (1972). The role of superoxide anion in the autooxidation of ephinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170-5.
18. Moron LS, Depierre JW, Mannervik B. (1979). Levels of glutathione, glutathione reductase, glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acta 582:67-78.
19. Muhit Md A, Khanam SS, Islam Md S, et al. (2010). Phytochemical and biological investigations of Pterospiermum acerifolium Willd bark. J Pharm Res 3:2643-6.
20. Muller D. (2001). New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414:821-7.
21. Navarro CM, Montilla PM, Martin A, et al. (1993). Free radicals scavenger and antihepatotoxic activity of Rosmarinus tomentosus. Planta Med 59:312-14.
22. Pellegrino M, Broca C, Gross R, et al. (1998). Development of a new model of type 2 diabetes in adult rats administered with streptozotocin and nicotinamide. Diabetes 47:224-9.
23. Shirwaikar A, Rajendran K, Punitha ISR. (2005). Antidiabetic activity of alcoholic stem extract of Coscinium fenestratum in streptozotocin-nicotinamide induced type 2 diabetic rats. J Ethnopharmacol 97: 36974.
24. Slater TF, Sawyer BC. (1971). The stimulatory effect of carbontetrachloride and other halogen alkane or peroxidative reaction in the rat liver function in-vitro. Biochem J 123:805-15.
25. Srinivasan K, Ramarao P. (2007). Animal models in type 2 diabetes research: An overview. Indian J Med Res 125:451-72.
26. Srinivasan S, Pari L. (2012). Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin nicotinamide generated oxidative stress induced diabetic rats. Chem Biol Interact 195:43-51.
27. Townsend DM, Tew KD, Tapiero H. (2003). The importance of glutathione in human disease. Biomed Pharmacother 57:145-55.
28. Watkins PJ. (2003). ABC of diabetes, cardiovascular disease, hypertension and lipids. Brit Med J 10:82-4.
29. WHO Expert Committee on Diabetes mellitus (1980). Technical Report Series 646, Second Report. Geneva: World Health Organization.
30. Yavari A. (2011). Glycosylated hemoglobin: The importance in management of type 2 diabetes. J Stress Physiol Biochem 7:122-9.