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Volumn 25, Issue 1, 2014, Pages 63-72

Gene therapy with beta-defensin 2 induces antitumor immunity and enhances local antitumor effects

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 2;

EID: 84891781300     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2013.161     Document Type: Article
Times cited : (24)

References (54)
  • 1
    • 33646516620 scopus 로고    scopus 로고
    • Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37
    • Aarbiou, J., Tjabringa, G. S., Verhoosel, R. M., et al. (2006). Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37. Inflamm. Res. 55, 119-127.
    • (2006) Inflamm. Res , vol.55 , pp. 119-127
    • Aarbiou, J.1    Tjabringa, G.S.2    Verhoosel, R.M.3
  • 2
    • 35948972112 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 on tumor cells in vitro inhibits subsequent tumor growth in vivo
    • Andreani, V., Gatti, G., Simonella, L., et al. (2007). Activation of Toll-like receptor 4 on tumor cells in vitro inhibits subsequent tumor growth in vivo. Cancer Res. 67, 10519-10527.
    • (2007) Cancer Res , vol.67 , pp. 10519-10527
    • Andreani, V.1    Gatti, G.2    Simonella, L.3
  • 3
    • 33746214819 scopus 로고    scopus 로고
    • New generation vaccine induces effective melanoma-specific CD8 + T cells in the circulation but not in the tumor site
    • Appay, V., Jandus, C., Voelter, V., et al. (2006). New generation vaccine induces effective melanoma-specific CD8 + T cells in the circulation but not in the tumor site. J. Immunol. 177, 1670-1678.
    • (2006) J. Immunol , vol.177 , pp. 1670-1678
    • Appay, V.1    Jandus, C.2    Voelter, V.3
  • 4
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and Steinman, R. M. (1998). Dendritic cells and the control of immunity. Nature 392, 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 0032998424 scopus 로고    scopus 로고
    • Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity
    • Biragyn, A., Tani, K., Grimm, M. C., et al. (1999). Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity. Nat. Biotechnol. 17, 253-258.
    • (1999) Nat. Biotechnol , vol.17 , pp. 253-258
    • Biragyn, A.1    Tani, K.2    Grimm, M.C.3
  • 7
    • 0035576242 scopus 로고    scopus 로고
    • Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens
    • Biragyn, A., Surenhu, M., Yang, D., et al. (2001). Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens. J. Immunol. 167, 6644-6653.
    • (2001) J. Immunol , vol.167 , pp. 6644-6653
    • Biragyn, A.1    Surenhu, M.2    Yang, D.3
  • 8
    • 0036829687 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent activation of dendritic cells by betadefensin 2
    • Biragyn, A., Ruffini, P. A., Leifer, C. A., et al. (2002). Toll-like receptor 4-dependent activation of dendritic cells by betadefensin 2. Science 298, 1025-1029.
    • (2002) Science , vol.298 , pp. 1025-1029
    • Biragyn, A.1    Ruffini, P.A.2    Leifer, C.A.3
  • 9
    • 34548761516 scopus 로고    scopus 로고
    • Tumorassociated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity
    • Biragyn, A., Schiavo, R., Olkhanud, P., et al. (2007). Tumorassociated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity. J. Immunol. 179, 1381-1388.
    • (2007) J. Immunol , vol.179 , pp. 1381-1388
    • Biragyn, A.1    Schiavo, R.2    Olkhanud, P.3
  • 10
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • Blanco, P., Palucka, A. K., Gill, M., et al. (2001). Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 294, 1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3
  • 11
    • 6344229337 scopus 로고    scopus 로고
    • MIP-3alpha transfection into a rodent tumor cell line increases intratumoral dendritic cell infiltration but enhances (facilitates) tumor growth and decreases immunogenicity
    • Bonnotte, B., Crittenden, M., Larmonier, N., et al. (2004). MIP-3alpha transfection into a rodent tumor cell line increases intratumoral dendritic cell infiltration but enhances (facilitates) tumor growth and decreases immunogenicity. J. Immunol. 173, 4929-4935.
    • (2004) J. Immunol , vol.173 , pp. 4929-4935
    • Bonnotte, B.1    Crittenden, M.2    Larmonier, N.3
  • 12
    • 0033637307 scopus 로고    scopus 로고
    • Dendritic cell biology and regulation of dendritic cell trafficking by chemokines
    • Caux, C., Ait-Yahia, S., Chemin, K., et al. (2000). Dendritic cell biology and regulation of dendritic cell trafficking by chemokines. Springer Semin. Immunopathol. 22, 345-369.
    • (2000) Springer Semin. Immunopathol , vol.22 , pp. 345-369
    • Caux, C.1    Ait-Yahia, S.2    Chemin, K.3
  • 13
    • 0035882540 scopus 로고    scopus 로고
    • Efficient antitumor immunity derived from maturation of dendritic cells that had phagocytosed apoptotic/necrotic tumor cells
    • Chen, Z., Moyana, T., Saxena, A., et al. (2001). Efficient antitumor immunity derived from maturation of dendritic cells that had phagocytosed apoptotic/necrotic tumor cells. Int. J. Cancer 93, 539-548.
    • (2001) Int. J. Cancer , vol.93 , pp. 539-548
    • Chen, Z.1    Moyana, T.2    Saxena, A.3
  • 14
    • 0033526861 scopus 로고    scopus 로고
    • Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte response
    • Chiodoni, C., Paglia, P., Stoppacciaro, A., et al. (1999). Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte response. J. Exp. Med. 190, 125-133.
    • (1999) J. Exp. Med , vol.190 , pp. 125-133
    • Chiodoni, C.1    Paglia, P.2    Stoppacciaro, A.3
  • 15
    • 4644345036 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A
    • Conejo-Garcia, J. R., Benencia, F., Courreges, M. C., et al. (2004). Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nat. Med. 10, 950-958.
    • (2004) Nat. Med , vol.10 , pp. 950-958
    • Conejo-Garcia, J.R.1    Benencia, F.2    Courreges, M.C.3
  • 16
    • 0035862333 scopus 로고    scopus 로고
    • Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
    • Dhodapkar, M. V., Steinman, R. M., Krasovsky, J., et al. (2001). Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193, 233-238.
    • (2001) J. Exp. Med , vol.193 , pp. 233-238
    • Dhodapkar, M.V.1    Steinman, R.M.2    Krasovsky, J.3
  • 17
    • 18944375915 scopus 로고    scopus 로고
    • IL-4-transfected tumor cell vaccines activate tumor-infiltrating dendritic cells and promote type-1 immunity
    • Eguchi, J., Kuwashima, N., Hatano, M., et al. (2005). IL-4-transfected tumor cell vaccines activate tumor-infiltrating dendritic cells and promote type-1 immunity. J. Immunol. 174, 7194-7201.
    • (2005) J. Immunol , vol.174 , pp. 7194-7201
    • Eguchi, J.1    Kuwashima, N.2    Hatano, M.3
  • 18
    • 7144253145 scopus 로고    scopus 로고
    • Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: Perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor
    • Fioretti, F., Fradelizi, D., Stoppacciaro, A., et al. (1998). Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor. J. Immunol. 161, 342-346.
    • (1998) J. Immunol , vol.161 , pp. 342-346
    • Fioretti, F.1    Fradelizi, D.2    Stoppacciaro, A.3
  • 19
    • 0034121654 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • Fong, L., and Engleman, E. G. (2000). Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 18, 245-273.
    • (2000) Annu. Rev. Immunol , vol.18 , pp. 245-273
    • Fong, L.1    Engleman, E.G.2
  • 20
    • 1842486876 scopus 로고    scopus 로고
    • Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
    • Furumoto, K., Soares, L., Engleman, E. G., and Merad, M. (2004). Induction of potent antitumor immunity by in situ targeting of intratumoral DCs. J. Clin. Invest. 113, 774-783.
    • (2004) J. Clin. Invest , vol.113 , pp. 774-783
    • Furumoto, K.1    Soares, L.2    Engleman, E.G.3    Merad, M.4
  • 21
    • 0034111112 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth
    • Fushimi, T., Kojima, A., Moore, M. A., and Crystal, R. G. (2000). Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth. J. Clin. Invest. 105, 1383-1393.
    • (2000) J. Clin. Invest , vol.105 , pp. 1383-1393
    • Fushimi, T.1    Kojima, A.2    Moore, M.A.3    Crystal, R.G.4
  • 22
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich, D. (2004). Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 4, 941-952.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 23
    • 33745310156 scopus 로고    scopus 로고
    • Prostate epithelial cells can act as early sensors of infection by up-regulating TLR4 expression and proinflammatory mediators upon LPS stimulation
    • Gatti, G., Rivero, V., Motrich, R. D., and Maccioni, M. (2006). Prostate epithelial cells can act as early sensors of infection by up-regulating TLR4 expression and proinflammatory mediators upon LPS stimulation. J. Leukoc. Biol. 79, 989-998.
    • (2006) J. Leukoc. Biol , vol.79 , pp. 989-998
    • Gatti, G.1    Rivero, V.2    Motrich, R.D.3    Maccioni, M.4
  • 24
    • 0026009980 scopus 로고
    • Human neutrophil peptide defensins induce single strand DNA breaks in target cells
    • Gera, J. F., and Lichtenstein, A. (1991). Human neutrophil peptide defensins induce single strand DNA breaks in target cells. Cell Immunol. 138, 108-120.
    • (1991) Cell Immunol , vol.138 , pp. 108-120
    • Gera, J.F.1    Lichtenstein, A.2
  • 25
    • 35748968488 scopus 로고    scopus 로고
    • Chemoattraction of macrophages, T lymphocytes, and mast cells is evolutionarily conserved within the human alpha-defensin family
    • Grigat, J., Soruri, A., Forssmann, U., et al. (2007). Chemoattraction of macrophages, T lymphocytes, and mast cells is evolutionarily conserved within the human alpha-defensin family. J. Immunol. 179, 3958-3965.
    • (2007) J. Immunol , vol.179 , pp. 3958-3965
    • Grigat, J.1    Soruri, A.2    Forssmann, U.3
  • 26
    • 0034655262 scopus 로고    scopus 로고
    • CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: Critical role in migration from the tumor site to draining lymph nodes
    • Hirao, M., Onai, N., Hiroishi, K., et al. (2000). CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes. Cancer Res. 60, 2209-2217.
    • (2000) Cancer Res , vol.60 , pp. 2209-2217
    • Hirao, M.1    Onai, N.2    Hiroishi, K.3
  • 27
    • 19344373919 scopus 로고    scopus 로고
    • Autoantigens signal through chemokine receptors: Uveitis antigens induce CXCR3-and CXCR5-expressing lymphocytes and immature dendritic cells to migrate
    • Howard, O. M., Dong, H. F., Su, S. B., et al. (2005). Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3-and CXCR5-expressing lymphocytes and immature dendritic cells to migrate. Blood 105, 4207-4214.
    • (2005) Blood , vol.105 , pp. 4207-4214
    • Howard, O.M.1    Dong, H.F.2    Su, S.B.3
  • 28
    • 34548476495 scopus 로고    scopus 로고
    • Defensins induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo
    • Hubert, P., Herman, L., Maillard, C., et al. (2007). Defensins induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo. FASEB J. 21, 2765-2775.
    • (2007) FASEB J , vol.21 , pp. 2765-2775
    • Hubert, P.1    Herman, L.2    Maillard, C.3
  • 29
    • 0037258397 scopus 로고    scopus 로고
    • Naive CD8 + T cell recruitment and proliferation are dependent on stage of dendritic cell maturation
    • Kaiser, A., Bercovici, N., Abastado, J. P., and Nardin, A. (2003). Naive CD8 + T cell recruitment and proliferation are dependent on stage of dendritic cell maturation. Eur. J. Immunol. 33, 162-171.
    • (2003) Eur. J. Immunol , vol.33 , pp. 162-171
    • Kaiser, A.1    Bercovici, N.2    Abastado, J.P.3    Nardin, A.4
  • 30
    • 34249677845 scopus 로고    scopus 로고
    • Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
    • Kanzler, H., Barrat, F. J., Hessel, E. M., and Coffman, R. L. (2007). Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat. Med. 13, 552-559.
    • (2007) Nat. Med , vol.13 , pp. 552-559
    • Kanzler, H.1    Barrat, F.J.2    Hessel, E.M.3    Coffman, R.L.4
  • 31
    • 33747865175 scopus 로고    scopus 로고
    • Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice
    • Khazanov, E., Simberg, D., and Barenholz, Y. (2006). Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice. J. Gene Med. 8, 998-1007.
    • (2006) J. Gene Med , vol.8 , pp. 998-1007
    • Khazanov, E.1    Simberg, D.2    Barenholz, Y.3
  • 32
    • 0035266293 scopus 로고    scopus 로고
    • T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: Augmentation of dendritic cellbased immunotherapy
    • Kirk, C. J., Hartigan-O'Connor, D., Nickoloff, B. J., et al. (2001). T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cellbased immunotherapy. Cancer Res. 61, 2062-2070.
    • (2001) Cancer Res , vol.61 , pp. 2062-2070
    • Kirk, C.J.1    Hartigan-O'connor, D.2    Nickoloff, B.J.3
  • 33
    • 35948999237 scopus 로고    scopus 로고
    • Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation
    • Lapteva, N., Seethammagari, M. R., Hanks, B. A., et al. (2007). Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation. Cancer Res. 67, 10528-10537.
    • (2007) Cancer Res , vol.67 , pp. 10528-10537
    • Lapteva, N.1    Seethammagari, M.R.2    Hanks, B.A.3
  • 34
    • 69949180750 scopus 로고    scopus 로고
    • Attraction and activation of dendritic cells at the site of tumor elicits potent antitumor immunity
    • Lapteva, N., Aldrich, M., Rollins, L., et al. (2009). Attraction and activation of dendritic cells at the site of tumor elicits potent antitumor immunity. Mol. Ther. 17, 1626-1636.
    • (2009) Mol. Ther , vol.17 , pp. 1626-1636
    • Lapteva, N.1    Aldrich, M.2    Rollins, L.3
  • 35
    • 0025738532 scopus 로고
    • Mechanism of mammalian cell lysis mediated by peptide defensins. Evidence for an initial alteration of the plasma membrane
    • Lichtenstein, A. (1991). Mechanism of mammalian cell lysis mediated by peptide defensins. Evidence for an initial alteration of the plasma membrane. J. Clin. Invest. 88, 93-100.
    • (1991) J. Clin. Invest , vol.88 , pp. 93-100
    • Lichtenstein, A.1
  • 36
    • 0022886732 scopus 로고
    • In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes
    • Lichtenstein, A., Ganz, T., Selsted, M. E., and Lehrer, R. I. (1986). In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood 68, 1407-1410.
    • (1986) Blood , vol.68 , pp. 1407-1410
    • Lichtenstein, A.1    Ganz, T.2    Selsted, M.E.3    Lehrer, R.I.4
  • 37
    • 31544445750 scopus 로고    scopus 로고
    • Vaccine with beta-defensin 2-transduced leukemic cells activates innate and adaptive immunity to elicit potent antileukemia responses
    • Ma, X. T., Xu, B., An, L. L., et al. (2006). Vaccine with beta-defensin 2-transduced leukemic cells activates innate and adaptive immunity to elicit potent antileukemia responses. Cancer Res. 66, 1169-1176.
    • (2006) Cancer Res , vol.66 , pp. 1169-1176
    • Ma, X.T.1    Xu, B.2    An, L.L.3
  • 38
    • 1842562212 scopus 로고    scopus 로고
    • Tolerance and cancer: Mechanisms of tumor evasion and strategies for breaking tolerance
    • Mapara, M. Y., and Sykes, M. (2004). Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J. Clin. Oncol. 22, 1136-1151.
    • (2004) J. Clin. Oncol , vol.22 , pp. 1136-1151
    • Mapara, M.Y.1    Sykes, M.2
  • 39
    • 84863120545 scopus 로고    scopus 로고
    • Beta-defensin 2 as an adjuvant promotes anti-melanoma immune responses and inhibits the growth of implanted murine melanoma in vivo
    • Mei, H. F., Jin, X. B., Zhu, J. Y., et al. (2012). Beta-defensin 2 as an adjuvant promotes anti-melanoma immune responses and inhibits the growth of implanted murine melanoma in vivo. PLoS One 7, e31328.
    • (2012) PLoS One , vol.7
    • Mei, H.F.1    Jin, X.B.2    Zhu, J.Y.3
  • 40
    • 18344416548 scopus 로고    scopus 로고
    • Human alpha-defensins HNPs-1,-2, and-3 in renal cell carcinoma: Influences on tumor cell proliferation
    • Muller, C. A., Markovic-Lipkovski, J., Klatt, T., et al. (2002). Human alpha-defensins HNPs-1,-2, and-3 in renal cell carcinoma: influences on tumor cell proliferation. Am. J. Pathol. 160, 1311-1324.
    • (2002) Am. J. Pathol , vol.160 , pp. 1311-1324
    • Muller, C.A.1    Markovic-Lipkovski, J.2    Klatt, T.3
  • 41
    • 0345447557 scopus 로고    scopus 로고
    • Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
    • Nair, S., McLaughlin, C., Weizer, A., et al. (2003). Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J. Immunol. 171, 6275-6282.
    • (2003) J. Immunol , vol.171 , pp. 6275-6282
    • Nair, S.1    McLaughlin, C.2    Weizer, A.3
  • 42
    • 0037446540 scopus 로고    scopus 로고
    • Host absence of CCR5 potentiates dendritic cell vaccination
    • Ng-Cashin, J., Kuhns, J. J., Burkett, S. E., et al. (2003). Host absence of CCR5 potentiates dendritic cell vaccination. J. Immunol. 170, 4201-4208.
    • (2003) J. Immunol , vol.170 , pp. 4201-4208
    • Ng-Cashin, J.1    Kuhns, J.J.2    Burkett, S.E.3
  • 43
    • 34147170633 scopus 로고    scopus 로고
    • Complex formation with plasmid DNA increases the cytotoxicity of cationic liposomes
    • Nguyen, L. T., Atobe, K., Barichello, J. M., et al. (2007). Complex formation with plasmid DNA increases the cytotoxicity of cationic liposomes. Biol. Pharm. Bull. 30, 751-757.
    • (2007) Biol. Pharm. Bull , vol.30 , pp. 751-757
    • Nguyen, L.T.1    Atobe, K.2    Barichello, J.M.3
  • 44
    • 34548780921 scopus 로고    scopus 로고
    • Dendritic cells trigger tumor cell death by a nitric oxide-dependent mechanism
    • Nicolas, A., Cathelin, D., Larmonier, N., et al. (2007). Dendritic cells trigger tumor cell death by a nitric oxide-dependent mechanism. J. Immunol. 179, 812-818.
    • (2007) J. Immunol , vol.179 , pp. 812-818
    • Nicolas, A.1    Cathelin, D.2    Larmonier, N.3
  • 45
    • 29644438266 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection
    • Preynat-Seauve, O., Schuler, P., Contassot, E., et al. (2006). Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection. J. Immunol. 176, 61-67.
    • (2006) J. Immunol , vol.176 , pp. 61-67
    • Preynat-Seauve, O.1    Schuler, P.2    Contassot, E.3
  • 46
    • 0035862336 scopus 로고    scopus 로고
    • Differentiation of T regulatory cells by immature dendritic cells
    • Roncarolo, M. G., Levings, M. K., and Traversari, C. (2001). Differentiation of T regulatory cells by immature dendritic cells. J. Exp. Med. 193, F5-F9.
    • (2001) J. Exp. Med. , vol.193
    • Roncarolo, M.G.1    Levings, M.K.2    Traversari, C.3
  • 48
    • 48949120130 scopus 로고    scopus 로고
    • Effective transduction by self-complementary adeno-associated viruses of human dendritic cells with no alteration of their natural characteristics
    • Shin, O., Kim, S. J., Lee, W. I., et al. (2008). Effective transduction by self-complementary adeno-associated viruses of human dendritic cells with no alteration of their natural characteristics. J. Gene Med. 10, 762-769.
    • (2008) J. Gene Med , vol.10 , pp. 762-769
    • Shin, O.1    Kim, S.J.2    Lee, W.I.3
  • 49
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman, K., and Liu, Y. J. (2002). Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2, 151-161.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 50
    • 34250324345 scopus 로고    scopus 로고
    • Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells
    • Stary, G., Bangert, C., Tauber, M., et al. (2007). Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. J. Exp. Med. 204, 1441-1451.
    • (2007) J. Exp. Med , vol.204 , pp. 1441-1451
    • Stary, G.1    Bangert, C.2    Tauber, M.3
  • 51
    • 32244445715 scopus 로고    scopus 로고
    • A novel dendritic cell subset involved in tumor immunosurveillance
    • Taieb, J., Chaput, N., Menard, C., et al. (2006). A novel dendritic cell subset involved in tumor immunosurveillance. Nat. Med. 12, 214-219.
    • (2006) Nat. Med , vol.12 , pp. 214-219
    • Taieb, J.1    Chaput, N.2    Menard, C.3
  • 52
    • 36749026293 scopus 로고    scopus 로고
    • Immunity against tumor angiogenesis induced by a fusion vaccine with murine {beta}-defensin 2 and mFlk-1
    • Wang, Y. S., Wang, G. Q., Wen, Y. J., et al. (2007). Immunity against tumor angiogenesis induced by a fusion vaccine with murine {beta}-defensin 2 and mFlk-1. Clin. Cancer Res. 13, 6779-6787.
    • (2007) Clin. Cancer Res , vol.13 , pp. 6779-6787
    • Wang, Y.S.1    Wang, G.Q.2    Wen, Y.J.3
  • 53
    • 0033569408 scopus 로고    scopus 로고
    • Betadefensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
    • Yang, D., Chertov, O., Bykovskaia, S. N., et al. (1999). Betadefensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286, 525-528.
    • (1999) Science , vol.286 , pp. 525-528
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3
  • 54
    • 0033844287 scopus 로고    scopus 로고
    • Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
    • Yang, D., Chen, Q., Chertov, O., and Oppenheim, J. J. (2000). Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J. Leukoc. Biol. 68, 9-14.
    • (2000) J. Leukoc. Biol , vol.68 , pp. 9-14
    • Yang, D.1    Chen, Q.2    Chertov, O.3    Oppenheim, J.J.4


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