메뉴 건너뛰기




Volumn 116, Issue 1, 2014, Pages 41-48

Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells

Author keywords

Chemoradiotherapy resistance; Glioblastoma; Irradiation; Nrf2; Temozolomide

Indexed keywords

TEMOZOLOMIDE; TRANSCRIPTION FACTOR NRF2;

EID: 84891769614     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-013-1260-x     Document Type: Article
Times cited : (35)

References (28)
  • 1
    • 56649083534 scopus 로고    scopus 로고
    • Dual roles of Nrf2 in cancer
    • 10.1016/j.phrs.2008.09.003 1:CAS:528:DC%2BD1cXhsVChurfO 2652397 18838122 10.1016/j.phrs.2008.09.003
    • Lau A, Villeneuve NF, Sun Z, Wong PK, Zhang DD (2008) Dual roles of Nrf2 in cancer. Pharmacol Res 58:262-270. doi: 10.1016/j.phrs.2008.09.003
    • (2008) Pharmacol Res , vol.58 , pp. 262-270
    • Lau, A.1    Villeneuve, N.F.2    Sun, Z.3    Wong, P.K.4    Zhang, D.D.5
  • 2
    • 2342514015 scopus 로고    scopus 로고
    • An important role of Nrf2-ARE pathway in the cellular defense mechanism
    • 1:CAS:528:DC%2BD2cXjtFWlur4%3D 15469687 10.5483/BMBRep.2004.37.2.139
    • Lee JM, Johnson JA (2004) An important role of Nrf2-ARE pathway in the cellular defense mechanism. J Biochem Mol Biol 37:139-143
    • (2004) J Biochem Mol Biol , vol.37 , pp. 139-143
    • Lee, J.M.1    Johnson, J.A.2
  • 3
    • 77649275857 scopus 로고    scopus 로고
    • Nrf2 signaling and cell survival
    • 10.1016/j.taap.2009.06.009 1:CAS:528:DC%2BC3cXjt1Gkt7Y%3D 2837794 19538984 10.1016/j.taap.2009.06.009
    • Niture SK, Kaspar JW, Shen J, Jaiswal AK (2010) Nrf2 signaling and cell survival. Toxicol Appl Pharmacol 244:37-42. doi: 10.1016/j.taap.2009.06.009
    • (2010) Toxicol Appl Pharmacol , vol.244 , pp. 37-42
    • Niture, S.K.1    Kaspar, J.W.2    Shen, J.3    Jaiswal, A.K.4
  • 4
    • 67650922529 scopus 로고    scopus 로고
    • Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells
    • 10.1016/j.ejca.2009.05.017 1:CAS:528:DC%2BD1MXptVShur8%3D 19524433 10.1016/j.ejca.2009.05.017
    • Akhdar H, Loyer P, Rauch C, Corlu A, Guillouzo A, Morel F (2009) Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells. Eur J Cancer 45:2219-2227. doi: 10.1016/j.ejca.2009.05.017
    • (2009) Eur J Cancer , vol.45 , pp. 2219-2227
    • Akhdar, H.1    Loyer, P.2    Rauch, C.3    Corlu, A.4    Guillouzo, A.5    Morel, F.6
  • 5
    • 77958129306 scopus 로고    scopus 로고
    • Gain of Nrf2 function in non-small-cell lung cancer cells confers radioresistance
    • 10.1089/ars 1:CAS:528:DC%2BC3cXht12ltL%2FN 20446773 10.1089/ars.2010.3219 2010.3219
    • Singh A, Bodas M, Wakabayashi N, Bunz F, Biswal S (2010) Gain of Nrf2 function in non-small-cell lung cancer cells confers radioresistance. Antioxid Redox Signal 13:1627-1637. doi: 10.1089/ars 2010.3219
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1627-1637
    • Singh, A.1    Bodas, M.2    Wakabayashi, N.3    Bunz, F.4    Biswal, S.5
  • 6
    • 38149003106 scopus 로고    scopus 로고
    • Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: Implication to cancer cell resistance
    • 10.1016/j.canlet.2007.10.022 1:CAS:528:DC%2BD1cXosFejuw%3D%3D 18036733 10.1016/j.canlet.2007.10.022
    • Cho JM, Manandhar S, Lee HR, Park HM, Kwak MK (2008) Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: implication to cancer cell resistance. Cancer Lett 260:96-108. doi: 10.1016/j.canlet.2007.10.022
    • (2008) Cancer Lett , vol.260 , pp. 96-108
    • Cho, J.M.1    Manandhar, S.2    Lee, H.R.3    Park, H.M.4    Kwak, M.K.5
  • 8
    • 33845964413 scopus 로고    scopus 로고
    • Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate
    • 10.1074/jbc.M604748200 1:CAS:528:DC%2BD28XhtFegsbvP 16950787 10.1074/jbc.M604748200
    • Kweon MH, Adhami VM, Lee JS, Mukhtar H (2006) Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate. J Biol Chem 281:33761-33772. doi: 10.1074/jbc.M604748200
    • (2006) J Biol Chem , vol.281 , pp. 33761-33772
    • Kweon, M.H.1    Adhami, V.M.2    Lee, J.S.3    Mukhtar, H.4
  • 10
    • 59549099432 scopus 로고    scopus 로고
    • Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury
    • 10.1155/2008/725174 2630405 19190763 10.1155/2008/725174
    • Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, Yang X, Chen G, Ji Y (2008) Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury. Mediators Inflamm 2008:725174. doi: 10.1155/2008/725174
    • (2008) Mediators Inflamm , vol.2008 , pp. 725174
    • Jin, W.1    Wang, H.2    Yan, W.3    Xu, L.4    Wang, X.5    Zhao, X.6    Yang, X.7    Chen, G.8    Ji, Y.9
  • 11
    • 75149171430 scopus 로고    scopus 로고
    • Ferulic acid protects human umbilical vein endothelial cells from radiation induced oxidative stress by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways
    • 10.1248/bpb.33.29 1:CAS:528:DC%2BC3cXos1Ont7c%3D 20045931 10.1248/bpb.33.29
    • Ma ZC, Hong Q, Wang YG, Tan HL, Xiao CR, Liang QD, Zhang BL, Gao Y (2010) Ferulic acid protects human umbilical vein endothelial cells from radiation induced oxidative stress by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways. Biol Pharm Bull 33:29-34. doi: 10.1248/bpb.33.29
    • (2010) Biol Pharm Bull , vol.33 , pp. 29-34
    • Ma, Z.C.1    Hong, Q.2    Wang, Y.G.3    Tan, H.L.4    Xiao, C.R.5    Liang, Q.D.6    Zhang, B.L.7    Gao, Y.8
  • 12
    • 84864405467 scopus 로고    scopus 로고
    • An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses
    • 10.1016/j.freeradbiomed.2012.05.038 22684019 10.1016/j.freeradbiomed. 2012.05.038
    • Lee S, Lim MJ, Kim MH, Yu CH, Yun YS, Ahn J, Song JY (2012) An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses. Free Radic Biol Med 53:807-816. doi: 10.1016/j.freeradbiomed.2012.05.038
    • (2012) Free Radic Biol Med , vol.53 , pp. 807-816
    • Lee, S.1    Lim, M.J.2    Kim, M.H.3    Yu, C.H.4    Yun, Y.S.5    Ahn, J.6    Song, J.Y.7
  • 13
    • 13644254921 scopus 로고    scopus 로고
    • Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities
    • 10.1186/1476-4598-3-36 544397 15588281 10.1186/1476-4598-3-36
    • Das A, Banik NL, Patel SJ, Ray SK (2004) Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. Mol Cancer 3:36. doi: 10.1186/1476-4598-3-36
    • (2004) Mol Cancer , vol.3 , pp. 36
    • Das, A.1    Banik, N.L.2    Patel, S.J.3    Ray, S.K.4
  • 14
    • 84863338153 scopus 로고    scopus 로고
    • Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury
    • 10.1089/neu 21806470 10.1089/neu.2011.1922 2011.1922
    • Wang X, de Rivero Vaccari JP, Wang H, Diaz P, German R, Marcillo AE, Keane RW (2011) Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury. J Neurotrauma 29:936-945. doi: 10.1089/neu 2011.1922
    • (2011) J Neurotrauma , vol.29 , pp. 936-945
    • Wang, X.1    De Rivero Vaccari, J.P.2    Wang, H.3    Diaz, P.4    German, R.5    Marcillo, A.E.6    Keane, R.W.7
  • 15
    • 84862004679 scopus 로고    scopus 로고
    • Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury
    • 10.1016/j.brainres.2012.05.014 1:CAS:528:DC%2BC38Xot1Oktbc%3D 22587887 10.1016/j.brainres.2012.05.014
    • Wang JW, Wang HD, Zhong WZ, Li N, Cong ZX (2012) Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury. Brain Res 1464:73-81. doi: 10.1016/j.brainres.2012.05. 014
    • (2012) Brain Res , vol.1464 , pp. 73-81
    • Wang, J.W.1    Wang, H.D.2    Zhong, W.Z.3    Li, N.4    Cong, Z.X.5
  • 16
    • 84885187547 scopus 로고    scopus 로고
    • The Role of Nrf2 in Migration and Invasion of Human Glioma Cell U251
    • 10.1016/j.wneu.2011.06.063
    • Pan H, Wang H, Zhu L, Mao L, Qiao L, Su X (2011) The Role of Nrf2 in Migration and Invasion of Human Glioma Cell U251. World Neurosurg. doi: 10.1016/j.wneu.2011.06.063
    • (2011) World Neurosurg
    • Pan, H.1    Wang, H.2    Zhu, L.3    Mao, L.4    Qiao, L.5    Su, X.6
  • 17
    • 77958140054 scopus 로고    scopus 로고
    • The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer
    • 10.1089/ars 1:CAS:528:DC%2BC3cXht12ltL%2FP 20486759 10.1089/ars.2010.3301 2010.3301
    • Zhang DD (2010) The Nrf2-Keap1-ARE signaling pathway: the regulation and dual function of Nrf2 in cancer. Antioxid Redox Signal 13:1623-1626. doi: 10.1089/ars 2010.3301
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1623-1626
    • Zhang, D.D.1
  • 18
    • 84872831679 scopus 로고    scopus 로고
    • Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line
    • 10.3892/or 1:CAS:528:DC%2BC3sXksl2ntA%3D%3D 23128449 2012.2115
    • Zhou Y, Wang HD, Zhu L, Cong ZX, Li N, Ji XJ, Pan H, Wang JW, Li WC (2013) Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line. Oncol Rep 29:394-400. doi: 10.3892/or 2012.2115
    • (2013) Oncol Rep , vol.29 , pp. 394-400
    • Zhou, Y.1    Wang, H.D.2    Zhu, L.3    Cong, Z.X.4    Li, N.5    Ji, X.J.6    Pan, H.7    Wang, J.W.8    Li, W.C.9
  • 20
    • 70350620150 scopus 로고    scopus 로고
    • Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway
    • 10.1016/j.freeradbiomed.2009.09.006 1:CAS:528:DC%2BD1MXhtlyrtbvL 19751820 10.1016/j.freeradbiomed.2009.09.006
    • Shim GS, Manandhar S, Shin DH, Kim TH, Kwak MK (2009) Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway. Free Radic Biol Med 47:1619-1631. doi: 10.1016/j.freeradbiomed. 2009.09.006
    • (2009) Free Radic Biol Med , vol.47 , pp. 1619-1631
    • Shim, G.S.1    Manandhar, S.2    Shin, D.H.3    Kim, T.H.4    Kwak, M.K.5
  • 21
    • 33845297317 scopus 로고    scopus 로고
    • Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of Nrf2 by cancer chemotherapeutic agents
    • 10.1158/0008-5472.CAN-06-2298 1:CAS:528:DC%2BD2sXivVyqt7w%3D 17108137 10.1158/0008-5472.CAN-06-2298
    • Wang XJ, Hayes JD, Wolf CR (2006) Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of Nrf2 by cancer chemotherapeutic agents. Cancer Res 66:10983-10994. doi: 10.1158/0008-5472.CAN-06-2298
    • (2006) Cancer Res , vol.66 , pp. 10983-10994
    • Wang, X.J.1    Hayes, J.D.2    Wolf, C.R.3
  • 22
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • 10.1016/j.drup.2004.01.004 1:CAS:528:DC%2BD2cXkt1Wquro%3D 15158766 10.1016/j.drup.2004.01.004
    • Pelicano H, Carney D, Huang P (2004) ROS stress in cancer cells and therapeutic implications. Drug Resist Updat 7:97-110. doi: 10.1016/j.drup.2004. 01.004
    • (2004) Drug Resist Updat , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 23
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • 10.1038/nrd2803 1:CAS:528:DC%2BD1MXmsFWqsLk%3D 19478820 10.1038/nrd2803
    • Trachootham D, Alexandre J, Huang P (2009) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 8:579-591. doi: 10.1038/nrd2803
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 24
    • 0031773901 scopus 로고    scopus 로고
    • Enzymatic processing of radiation-induced free radical damage in DNA
    • 1:CAS:528:DyaK1cXnt1Cqsro%3D 9806610 10.2307/3579809
    • Wallace SS (1998) Enzymatic processing of radiation-induced free radical damage in DNA. Radiat Res 150:S60-S79
    • (1998) Radiat Res , vol.150
    • Wallace, S.S.1
  • 25
    • 79955591154 scopus 로고    scopus 로고
    • Radioprotective effect of geraniin via the inhibition of apoptosis triggered by γ-radiation-induced oxidative stress
    • 10.1007/s10565-010-9172-4 20680428 10.1007/s10565-010-9172-4
    • Kang KA, Lee IK, Zhang R, Piao MJ, Kim KC, Kim SY, Shin T, Kim BJ, Lee NH, Hyun JW (2010) Radioprotective effect of geraniin via the inhibition of apoptosis triggered by γ-radiation-induced oxidative stress. Cell Biol Toxicol 27:83-94. doi: 10.1007/s10565-010-9172-4
    • (2010) Cell Biol Toxicol , vol.27 , pp. 83-94
    • Kang, K.A.1    Lee, I.K.2    Zhang, R.3    Piao, M.J.4    Kim, K.C.5    Kim, S.Y.6    Shin, T.7    Kim, B.J.8    Lee, N.H.9    Hyun, J.W.10
  • 26
    • 33845904383 scopus 로고    scopus 로고
    • The Response of CD24-/low/CD44+breast cancer-initiating cells to radiation
    • 10.1093/jnci/djj495 17179479 10.1093/jnci/djj495
    • Phillips TM, McBride WH, Pajonk F (2006) The Response of CD24-/low/CD44+breast cancer-initiating cells to radiation. J Natl Cancer Inst 98:1777-1785. doi: 10.1093/jnci/djj495
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 27
    • 84855450663 scopus 로고    scopus 로고
    • Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy
    • 10.1016/j.freeradbiomed.2011.10.487 1:CAS:528:DC%2BC38XlsVyiuw%3D%3D 22094224 10.1016/j.freeradbiomed.2011.10.487
    • Lin CJ, Lee CC, Shih YL, Lin TY, Wang SH, Lin YF, Shih CM (2012) Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy. Free Radic Biol Med 52:377-391. doi: 10.1016/j.freeradbiomed.2011.10.487
    • (2012) Free Radic Biol Med , vol.52 , pp. 377-391
    • Lin, C.J.1    Lee, C.C.2    Shih, Y.L.3    Lin, T.Y.4    Wang, S.H.5    Lin, Y.F.6    Shih, C.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.