Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury

Brain Research

Volumn 1464, Issue , 2012, Pages 73-81

  Wang, Jia Wei ^a   Wang, Han Dong ^a   Zhong, Wu Zhao ^b   Li, Ning ^c   Cong, Zi Xiang ^a  

^a NANJING UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Expression; Fluoro Jade C; Metabotropic glutamate receptor 5; Rat cortex; Traumatic brain injury

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; METABOTROPIC RECEPTOR 5; NEURON SPECIFIC NUCLEAR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN NERVE CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRAUMATIC BRAIN INJURY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; EXCITATORY AMINO ACID AGONISTS; GLYCINE; MALE; NERVE DEGENERATION; NEURONS; PHENYLACETATES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; TISSUE DISTRIBUTION;

RATTUS;

EID: 84862004679     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.05.014     Document Type: Article

References (43)

1. J.W. Allen, S.M. Knoblach, and A.I. Faden Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro Cell Death Differ. 7 2000 470 476
2. E. Aronica, M.V. Catania, J. Geurts, B. Yankaya, and D. Troost Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes Neuroscience 105 2001 509 520
3. P. Backstrom, and P. Hyytia Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats Psychopharmacology (Berl) 192 2007 571 580
4. W.L. Bao, A.J. Williams, A.I. Faden, and F.C. Tortella Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia Brain Res. 922 2001 173 179
5. K. Biber, D.J. Laurie, A. Berthele, B. Sommer, T.R. Tolle, P.J. Gebicke-Harter, D. van Calker, and H.W. Boddeke Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia J. Neurochem. 72 1999 1671 1680
6. V. Bruno, G. Battaglia, A. Copani, M. D'Onofrio, P. Di Iorio, A. De Blasi, D. Melchiorri, P.J. Flor, and F. Nicoletti Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs J. Cereb. Blood Flow Metab. 21 2001 1013 1033
7. K.R. Byrnes, D.J. Loane, and A.I. Faden Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders Neurotherapeutics 6 2009 94 107
8. K.R. Byrnes, B. Stoica, D.J. Loane, A. Riccio, M.I. Davis, and A.I. Faden Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity Glia 57 2009 550 560
9. K.R. Byrnes, D.J. Loane, B.A. Stoica, J. Zhang, and A.I. Faden Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury J. Neuroinflammation 9 2012 43
10. M.V. Catania, M. Bellomo, V. Di Giorgi-Gerevini, G. Seminara, R. Giuffrida, R. Romeo, A. De Blasi, and F. Nicoletti Endogenous activation of group-I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells J. Neurosci. 21 2001 7664 7673
11. G. Chen, S. Zhang, J. Shi, J. Ai, M. Qi, and C. Hang Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway Exp. Neurol. 216 2009 398 406
12. T. Chen, L. Cao, W. Dong, P. Luo, W. Liu, Y. Qu, and Z. Fei Protective effects of mGluR5 positive modulators against traumatic neuronal injury through PKC-dependent activation of MEK/ERK pathway Neurochem. Res. 37 2012 983 990
13. T. Chen, L. Zhang, Y. Qu, K. Huo, X. Jiang, and Z. Fei The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway Int. J. Mol. Med. 29 2012 630 636
14. Z. Chu, and S.M. Moenter Endogenous activation of metabotropic glutamate receptors modulates GABAergic transmission to gonadotropin-releasing hormone neurons and alters their firing rate: a possible local feedback circuit J. Neurosci. 25 2005 5740 5749
15. R. Ciccarelli, F.X. Sureda, G. Casabona, P. Di Iorio, A. Caruso, F. Spinella, D.F. Condorelli, F. Nicoletti, and F. Caciagli Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture Glia 21 1997 390 398
16. C. Corti, R.W. Clarkson, L. Crepaldi, C.F. Sala, J.H. Xuereb, and F. Ferraguti Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells J. Biol. Chem. 278 2003 33105 33119
17. S.A. Dutcher, B.D. Underwood, P.D. Walker, F.G. Diaz, and D.B. Michael Patterns of immediate early gene mRNA expression following rodent and human traumatic brain injury Neurol. Res. 21 1999 234 242
18. A. Faden, P. Demediuk, S. Panter, and R. Vink The role of excitatory amino acids and NMDA receptors in traumatic brain injury Science 244 1989 798 800
19. D.M. Feeney, M.G. Boyeson, R.T. Linn, H.M. Murray, and W.G. Dail Responses to cortical injury: I. Methodology and local effects of contusions in the rat Brain Res. 211 1981 67 77
20. J.J. Geurts, G. Wolswijk, L. Bo, P. van der Valk, C.H. Polman, D. Troost, and E. Aronica Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis Brain 126 2003 1755 1766
21. Q.Z. Gong, L.L. Phillips, and B.G. Lyeth Metabotropic glutamate receptor protein alterations after traumatic brain injury in rats J. Neurotrauma 16 1999 893 902
22. S.C. Harney, M. Rowan, and R. Anwyl Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering J. Neurosci. 26 2006 1128 1132
23. R. Hayes, K. Yang, R. Raghupathi, and T. McIntosh Changes in gene expression following traumatic brain injury in the rat J. Neurotrauma 12 1995 779 790
24. G.W. Hubert, M. Paquet, and Y. Smith Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey substantia nigra J. Neurosci. 21 2001 1838 1847
25. Y.J. Jong, V. Kumar, and K.L. O'Malley Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts J. Biol. Chem. 284 2009 35827 35838
26. S.A. Kotecha, M.F. Jackson, A. Al-Mahrouki, J.C. Roder, B.A. Orser, and J.F. MacDonald Co-stimulation of mGluR5 and N-methyl-d-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons J. Biol. Chem. 278 2003 27742 27749
27. P.M. Lea, S.J. Custer, S. Vicini, and A.I. Faden Neuronal and glial mGluR5 modulation prevents stretch-induced enhancement of NMDA receptor current Pharmacol. Biochem. Behav. 73 2002 287 298
28. P.T. Lea, V.A. Movsesyan, and A.I. Faden Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors Br. J. Pharmacol. 145 2005 527 534
29. D.J. Loane, B.A. Stoica, A. Pajoohesh-Ganji, K.R. Byrnes, and A.I. Faden Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase J. Biol. Chem. 284 2009 15629 15639
30. V.A. Movsesyan, B.A. Stoica, and A.I. Faden MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor J. Neurochem. 89 2004 1528 1536
31. G. Mudo, A. Trovato-Salinaro, G. Caniglia, Q. Cheng, and D.F. Condorelli Cellular localization of mGluR3 and mGluR5 mRNAs in normal and injured rat brain Brain Res. 1149 2007 1 13
32. P. Nilsson, L. Hillered, U. Ponten, and U. Ungerstedt Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats J. Cereb. Blood Flow Metab. 10 1990 631 637
33. O. Sanz, L. Acarin, B. Gonzalez, and B. Castellano NF-kappaB and IkappaBalpha expression following traumatic brain injury to the immature rat brain J. Neurosci. Res. 67 2002 772 780
34. T.D. Schmittgen, and K.J. Livak Analyzing real-time PCR data by the comparative C(T) method Nat. Protoc. 3 2008 1101 1108
35. L.C. Schmued, C.C. Stowers, A.C. Scallet, and L. Xu Fluoro-Jade C results in ultra-high resolution and contrast labeling of degenerating neurons Brain Res. 1035 2005 24 31
36. A. Simonyi, T.R. Schachtman, and G.R. Christoffersen Metabotropic glutamate receptor subtype 5 antagonism in learning and memory Eur. J. Pharmacol. 639 2010 17 25
37. A.B. Spillson, and J.W. Russell Metabotropic glutamate receptor regulation of neuronal cell death Exp. Neurol. 184 2003 s97 s105
38. P.G. Szekeres, J.A. Koenig, and J.M. Edwardson Involvement of receptor cycling and receptor reserve in resensitization of muscarinic responses in SH-SY5Y human neuroblastoma cells J. Neurochem. 70 1998 1694 1703
39. X. Wang, K. Moussawi, L. Knackstedt, H. Shen, and P.W. Kalivas Role of mGluR5 neurotransmission in reinstated cocaine-seeking Addict. Biol. 2012 10.1111/.1369-1600.2011.00432.x
40. X. Xu, J. Zhang, X. Chen, J. Liu, H. Lu, P. Yang, X. Xiao, L. Zhao, Q. Jiao, B. Zhao, P. Zheng, and Y. Liu The increased expression of metabotropic glutamate receptor 5 in subventricular zone neural progenitor cells and enhanced neurogenesis in a rat model of intracerebral hemorrhage Neuroscience 202 2012 474 483
41. S. Yamaguchi, and S. Nakanishi Regional expression and regulation of alternative forms of mRNAs derived from two distinct transcription initiation sites of the rat mGluR5 gene J. Neurochem. 71 1998 60 68
42. N. Yanamala, K.C. Tirupula, and J. Klein-Seetharaman Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors BMC Bioinforma. 9 Suppl. 1 2008 S16
43. K. Yang, X.S. Mu, J.J. Xue, J. Whitson, A. Salminen, C.E. Dixon, P.K. Liu, and R.L. Hayes Increased expression of c-fos mRNA and AP-1 transcription factors after cortical impact injury in rats Brain Res. 664 1994 141 147