Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries

Diabetes Care

Volumn 36, Issue 9, 2013, Pages 2621-2627

  Zheng, Ju Sheng ^a,b   Arnett, Donna K ^c   Parnell, Laurence D ^b   Smith, Caren E ^b   Li, Duo ^a   Borecki, Ingrid B ^d   Tucker, Katherine L ^e   Ordovás, José M ^b   Lai, Chao Qiang ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b TUFTS UNIVERSITY   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; FATTY ACID; INSULIN; INSULIN RECEPTOR SUBSTRATE 1;

ARTICLE; CARBOHYDRATE DIET; CARBOHYDRATE TO FATTY ACID RATIO; DIET RESTRICTION; DISEASE ASSOCIATION; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; HUMAN; INSULIN RECEPTOR SUBSTRATE 1 GENE; INSULIN RESISTANCE; LIFESTYLE MODIFICATION; LIPID DIET; META ANALYSIS; METABOLIC PARAMETERS; MOLECULAR DYNAMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PHENOTYPE; PROTEIN DETERMINATION; PROTEIN FUNCTION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE;

ADULT; ALLELES; DIABETES MELLITUS, TYPE 2; DIETARY CARBOHYDRATES; DIETARY FATS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MIDDLE AGED;

EID: 84891759420     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-2607     Document Type: Article

References (34)

1. Centers forDiseaseControl and Prevention. National Diabetes Fact Sheet: United States 2011. Atlanta, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, 2011
2. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87: 4-14
3. Grundy SM, Cleeman JI, Daniels SR, et al.; American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/ National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112: 2735-2752
4. Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009;106: 9362-9367
5. Voight BF, Scott LJ, Steinthorsdottir V, et al.; MAGIC investigators; GIANT Consortium. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010;42: 579-589
6. Cornelis MC, Hu FB. Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges. Annu Rev Nutr 2012;32: 245-259
7. Rung J, Cauchi S, Albrechtsen A, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009;41: 1110-1115
8. Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002;296: 1655-1657
9. Boura-Halfon S, Zick Y. Phosphorylation of IRS proteins, insulin action, and insulin resistance. AmJ Physiol EndocrinolMetab 2009;296:E581-E591
10. Thirone AC, Huang C, Klip A. Tissuespecific roles of IRS proteins in insulin signaling and glucose transport. Trends Endocrinol Metab 2006;17: 72-78
11. Yamauchi T, Tobe K, Tamemoto H, et al. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice. Mol Cell Biol 1996;16: 3074-3084
12. Kaburagi Y, Satoh S, Tamemoto H, et al. Role of insulin receptor substrate-1 and pp60 in the regulation of insulin-induced glucose transport and GLUT4 translocation in primary adipocytes. J Biol Chem 1997; 272: 25839-25844
13. Qi Q, Bray GA, Smith SR, Hu FB, Sacks FM, Qi L. Insulin receptor substrate 1 gene variation modifies insulin resistance response to weight-loss diets in a 2-year randomized trial: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial. Circulation 2011; 124: 563-571
14. Ericson U, Rukh G, Stojkovic I, et al. Sexspecific interactions between the IRS1 polymorphism and intakes of carbohydrates and fat on incident type 2 diabetes. Am J Clin Nutr 2013;97: 208-216
15. Lorenzo C, Okoloise M, Williams K, Stern MP, Haffner SM; San Antonio Heart Study. The metabolic syndrome as predictor of type 2 diabetes: the San Antonio heart study. Diabetes Care 2003;26: 3153-3159
16. Wilson PWF, D'Agostino RB, Parise H, Sullivan L, Meigs JB. Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005; 112: 3066-3072
17. Shen J, Arnett DK, Peacock JM, et al. Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J Nutr 2007;137: 1846-1851
18. Ordovas JM, Shen J. Gene-environment interactions and susceptibility to metabolic syndrome and other chronic diseases. J Periodontol 2008;79(Suppl): 1508-1513
19. Corella D, Arnett DK, Tsai MY, et al. The -256T.C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. Clin Chem 2007;53: 1144-1152
20. Subar AF, Thompson FE, Kipnis V, et al. Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires : the Eating at America's Table Study. Am J Epidemiol 2001;154: 1089-1099
21. Thompson FE, Subar AF, Brown CC, et al. Cognitive research enhances accuracy of food frequency questionnaire reports: results of an experimental validation study. J Am Diet Assoc 2002;102: 212-225
22. Salmerón J, Manson JE, Stampfer MJ, Colditz GA, Wing AL, Willett WC.Dietary fiber, glycemic load, and risk of non-insulindependent diabetes mellitus in women. JAMA 1997;277: 472-477
23. Tucker KL, Mattei J, Noel SE, et al. The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities. BMC Public Health 2010;10: 107
24. Lai CQ, Tucker KL, Choudhry S, et al. Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet 2009;125: 199-209
25. Tucker KL, Bianchi LA, Maras J, Bermudez OI. Adaptation of a food frequency questionnaire to assess diets of Puerto Rican and non-Hispanic adults. AmJ Epidemiol 1998; 148: 507-518
26. van Rompay MI, McKeown NM, Castaneda-Sceppa C, Falcón LM, Ordovás JM, Tucker KL. Acculturation and sociocultural influences on dietary intake and health status among Puerto Rican adults in Massachusetts. J Acad Nutr Diet 2012;112: 64-74
27. Tsai MY, Hanson NQ, Straka RJ, et al. Effect of influenza vaccine on markers of inflammation and lipid profile. J Lab Clin Med 2005;145: 323-327
28. Box GEP, Cox DR. An analysis of transformations. J R Stat Soc Series B Stat Methodol 1964;26: 211-252
29. Pérez MS, Tellechea ML, Aranguren F, et al. The rs1801278 G.A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status. Diabetes Res Clin Pract 2011;93:e95-e97
30. Jellema A, Zeegers MPA, Feskens EJM, Dagnelie PC, Mensink RP. Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes: ameta-analysis of 27 studies. Diabetologia 2003;46: 990-995
31. Baroni MG, Leonetti F, Sentinelli F, et al. The G972R variant of the insulin receptor substrate-1 (IRS-1) gene is associated with insulin resistance in "uncomplicated" obese subjects evaluated by hyperinsulinemiceuglycemic clamp. J Endocrinol Invest 2004;27: 754-759
32. Kilpeläinen TO, Zillikens MC, Stančákova A, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.Nat Genet 2011; 43: 753-760
33. Samuel VT, Petersen KF, Shulman GI. Lipidinduced insulin resistance: unravelling the mechanism. Lancet 2010;375: 2267-2277
34. Willett W, Manson J, Liu S. Glycemic index, glycemic load, and risk of type 2 diabetes. Am J Clin Nutr 2002;76:274S-280S