Insulin receptor substrate 1 gene variation modifies insulin resistance response to weight-loss diets in a 2-year randomized trial the preventing overweight using novel dietary strategies (POUNDS LOST) Trial

Circulation

Volumn 124, Issue 5, 2011, Pages 563-571

  Qi, Qibin ^a   Bray, George A ^c,d   Smith, Steven R ^e   Hu, Frank B ^a,b   Sacks, Frank M ^a   Qi, Lu ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b Departments of Epidemiology and Biostatistics   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^e Translational Research Institute for Metabolism and Diabetes   (United States)

Author keywords

Diet; Genetic variation; Insulin; Weight loss

Indexed keywords

CARBOHYDRATE; FAT; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITROGEN; PROTEIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CARBOHYDRATE DIET; CHOLESTEROL BLOOD LEVEL; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; DIET RESTRICTION; DIET THERAPY; FEMALE; GENETIC VARIABILITY; GENOTYPE; GENOTYPE TIME INTERACTION; HOMEOSTASIS MODEL ASSESSMENTOF INSULIN RESISTANCE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MACRONUTRIENT; MAJOR CLINICAL STUDY; MALE; NITROGEN URINE LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ADULT; DIET, REDUCING; DIETARY CARBOHYDRATES; DIETARY FATS; DIETARY PROTEINS; ENERGY INTAKE; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MIDDLE AGED; OVERWEIGHT; RISK FACTORS; WEIGHT LOSS;

EID: 80051548943     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.025767     Document Type: Article

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