메뉴 건너뛰기




Volumn 63, Issue 2, 2014, Pages 272-280

Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; BACTERIAL DNA; DRUG ANTIBODY; GAMMA INTERFERON; INFLIXIMAB; INTERLEUKIN 12P40; MESALAZINE; METHOTREXATE; STEROID; TUMOR NECROSIS FACTOR ALPHA;

EID: 84891746717     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2012-303557     Document Type: Article
Times cited : (60)

References (49)
  • 1
    • 68349157701 scopus 로고    scopus 로고
    • Distribution and manifestations of inflammatory bowel disease in Asians, Hispanics, and African Americans: A systematic review
    • Hou JK, El-Serag H, Thirumurthi S. Distribution and manifestations of inflammatory bowel disease in Asians, Hispanics, and African Americans: a systematic review. Am J Gastroenterol 2009;104:2100-9.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2100-2109
    • Hou, J.K.1    El-Serag, H.2    Thirumurthi, S.3
  • 2
    • 68049113587 scopus 로고    scopus 로고
    • The evolving epidemiology of inflammatory bowel disease
    • Shanahan F, Bernstein CN. The evolving epidemiology of inflammatory bowel disease. Curr Opin Gastroenterol 2009;25:301-5.
    • (2009) Curr Opin Gastroenterol , vol.25 , pp. 301-305
    • Shanahan, F.1    Bernstein, C.N.2
  • 3
    • 23344449020 scopus 로고    scopus 로고
    • Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
    • DOI 10.1111/j.0105-2896.2005.00291.x
    • Elson CO, Cong Y, McCracken VJ, et al. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev 2005;206:260-76. (Pubitemid 41105175)
    • (2005) Immunological Reviews , vol.206 , pp. 260-276
    • Elson, C.O.1    Cong, Y.2    McCracken, V.J.3    Dimmitt, R.A.4    Lorenz, R.G.5    Weaver, C.T.6
  • 5
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • DOI 10.1056/NEJMra020831
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002;347:417-29. (Pubitemid 34851835)
    • (2002) New England Journal of Medicine , vol.347 , Issue.6 , pp. 417-429
    • Podolsky, D.K.1
  • 6
    • 0030830553 scopus 로고    scopus 로고
    • Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases
    • Sartor RB. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am J Gastroenterol 1997;92(12 Suppl):5S-11S.
    • (1997) Am J Gastroenterol , vol.92 , Issue.12 SUPPL.
    • Sartor, R.B.1
  • 7
    • 67650139597 scopus 로고    scopus 로고
    • Cytokine association with bacterial DNA in serum of patients with inflammatory bowel disease
    • Gutierrez A, Frances R, Amoros A, et al. Cytokine association with bacterial DNA in serum of patients with inflammatory bowel disease. Inflamm Bowel Dis 2009;15:508-14.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 508-514
    • Gutierrez, A.1    Frances, R.2    Amoros, A.3
  • 8
    • 79960242149 scopus 로고    scopus 로고
    • Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype
    • Gutierrez A, Holler E, Zapater P, et al. Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype. Inflamm Bowel Dis 2011;17:1641-50.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1641-1650
    • Gutierrez, A.1    Holler, E.2    Zapater, P.3
  • 11
    • 0035895992 scopus 로고    scopus 로고
    • Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
    • Ogura Y, Inohara N, Benito A, et al. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 2001;276:4812-18.
    • (2001) J Biol Chem , vol.276 , pp. 4812-4818
    • Ogura, Y.1    Inohara, N.2    Benito, A.3
  • 13
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-25.
    • (2010) Nat Genet , vol.42 , pp. 1118-1125
    • Franke, A.1    McGovern, D.P.2    Barrett, J.C.3
  • 14
    • 80655149205 scopus 로고    scopus 로고
    • New IBD genetics: Common pathways with other diseases
    • Lees CW, Barrett JC, Parkes M, et al. New IBD genetics: common pathways with other diseases. Gut 2011;60:1739-53.
    • (2011) Gut , vol.60 , pp. 1739-1753
    • Lees, C.W.1    Barrett, J.C.2    Parkes, M.3
  • 16
    • 35848970794 scopus 로고    scopus 로고
    • Erratum: Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease (Autophagy)
    • Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy 2007;3:649-51. (Pubitemid 350060072)
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 649-651
    • Massey, D.C.O.1    Parkes, M.2
  • 18
    • 34447629523 scopus 로고    scopus 로고
    • Innate and Adaptive Immunity through Autophagy
    • DOI 10.1016/j.immuni.2007.07.004, PII S1074761307003408
    • Schmid D, Munz C. Innate and adaptive immunity through autophagy. Immunity 2007;27:11-21. (Pubitemid 47089030)
    • (2007) Immunity , vol.27 , Issue.1 , pp. 11-21
    • Schmid, D.1    Munz, C.2
  • 19
    • 54849421128 scopus 로고    scopus 로고
    • Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
    • Kuballa P, Huett A, Rioux JD, et al. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One 2008;3:e3391.
    • (2008) PLoS One , vol.3
    • Kuballa, P.1    Huett, A.2    Rioux, J.D.3
  • 20
    • 77957682295 scopus 로고    scopus 로고
    • ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
    • 1641
    • Homer CR, Richmond AL, Rebert NA, et al. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology 2010;139:1630-41, 1641.
    • (2010) Gastroenterology , vol.139 , pp. 1630-1641
    • Homer, C.R.1    Richmond, A.L.2    Rebert, N.A.3
  • 21
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    • Sanjuan MA, Dillon CP, Tait SW, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007;450:1253-7.
    • (2007) Nature , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.3
  • 22
    • 48249109916 scopus 로고    scopus 로고
    • Eating for good health: Linking autophagy and phagocytosis in host defense
    • Sanjuan MA, Green DR. Eating for good health: linking autophagy and phagocytosis in host defense. Autophagy 2008;4:607-11.
    • (2008) Autophagy , vol.4 , pp. 607-611
    • Sanjuan, M.A.1    Green, D.R.2
  • 23
    • 2442613767 scopus 로고    scopus 로고
    • From symptom to diagnosis: Clinical distinctions among various forms of intestinal inflammation
    • DOI 10.1053/j.gastro.2004.02.072
    • Sands BE. From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation. Gastroenterology 2004;126:1518-32. (Pubitemid 38649870)
    • (2004) Gastroenterology , vol.126 , Issue.6 , pp. 1518-1532
    • Sands, B.E.1
  • 24
    • 84894353884 scopus 로고    scopus 로고
    • Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
    • Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005;19(Suppl A):5-36.
    • (2005) Can J Gastroenterol , vol.19 , Issue.SUPPL. A , pp. 5-36
    • Silverberg, M.S.1    Satsangi, J.2    Ahmad, T.3
  • 27
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 2007;447:661-78.
    • (2007) Nature , vol.447 , pp. 661-678
  • 29
    • 11144279151 scopus 로고    scopus 로고
    • Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
    • DOI 10.1111/j.1572-0241.2004.40304.x
    • Economou M, Trikalinos TA, Loizou KT, et al. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 2004;99:2393-404. (Pubitemid 40039371)
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.12 , pp. 2393-2404
    • Economou, M.1    Trikalinos, T.A.2    Loizou, K.T.3    Tsianos, E.V.4    Ioannidis, J.P.A.5
  • 30
    • 0036080129 scopus 로고    scopus 로고
    • The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease [2]
    • Radlmayr M, Torok HP, Martin K, et al. The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease. Gastroenterology 2002;122:2091-2. (Pubitemid 34651452)
    • (2002) Gastroenterology , vol.122 , Issue.7 , pp. 2091-2092
    • Radlmayr, M.1    Torok, H.P.2    Martin, K.3    Folwaczny, C.4
  • 31
    • 67650514274 scopus 로고    scopus 로고
    • Epistasis between toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
    • Torok HP, Glas J, Endres I, et al. Epistasis between toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol 2009;104:1723-33.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1723-1733
    • Torok, H.P.1    Glas, J.2    Endres, I.3
  • 37
    • 77951974444 scopus 로고    scopus 로고
    • Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease
    • Afif W, Loftus EV Jr, Faubion WA, et al. Clinical utility of measuring infliximab and human anti-chimeric antibody concentrations in patients with inflammatory bowel disease. Am J Gastroenterol 2010;105:1133-9.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1133-1139
    • Afif, W.1    Loftus Jr., E.V.2    Faubion, W.A.3
  • 38
    • 70350645060 scopus 로고    scopus 로고
    • Individual medicine in inflammatory bowel disease: Monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies
    • Bendtzen K, Ainsworth M, Steenholdt C, et al. Individual medicine in inflammatory bowel disease: monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies. Scand J Gastroenterol 2009;44:774-81.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 774-781
    • Bendtzen, K.1    Ainsworth, M.2    Steenholdt, C.3
  • 39
    • 84855648247 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of biologics for inflammatory bowel disease
    • Colombel JF, Feagan BG, Sandborn WJ, et al. Therapeutic drug monitoring of biologics for inflammatory bowel disease. Inflamm Bowel Dis 2012;18:349-58.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 349-358
    • Colombel, J.F.1    Feagan, B.G.2    Sandborn, W.J.3
  • 40
    • 75149145545 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of monoclonal antibodies: Concepts and lessons for drug development
    • Mould DR, Green B. Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development. Bio Drugs 2010;24:23-39.
    • (2010) Bio Drugs , vol.24 , pp. 23-39
    • Mould, D.R.1    Green, B.2
  • 41
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med 2010;362:1383-95.
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 42
    • 79955557278 scopus 로고    scopus 로고
    • Conventional medical management of inflammatory bowel disease
    • Burger D, Travis S. Conventional medical management of inflammatory bowel disease. Gastroenterology 2011;140:1827-37.
    • (2011) Gastroenterology , vol.140 , pp. 1827-1837
    • Burger, D.1    Travis, S.2
  • 44
    • 84876411893 scopus 로고    scopus 로고
    • Mucosal healing in Crohn's disease: A systematic review
    • Published Online First: 26 April, doi: 10.1002/ibd.22977
    • De CP, Kamm MA, Prideaux L, et al. Mucosal healing in Crohn's disease: a systematic review. Inflamm Bowel Dis Published Online First: 26 April 2012. doi: 10.1002/ibd.22977
    • (2012) Inflamm Bowel Dis
    • De, C.P.1    Kamm, M.A.2    Prideaux, L.3
  • 45
    • 0027244454 scopus 로고
    • Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans
    • Bjarnason I, Hayllar J, MacPherson AJ, et al. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993;104:1832-47. (Pubitemid 23235480)
    • (1993) Gastroenterology , vol.104 , Issue.6 , pp. 1832-1847
    • Bjarnason, I.1    Hayllar, J.2    MacPherson, A.J.3    Russell, A.S.4
  • 46
    • 10644266224 scopus 로고    scopus 로고
    • Systematic review: Is ingestion of paracetamol or non-steroidal anti-inflammatory drugs associated with exacerbations of inflammatory bowel disease?
    • DOI 10.1111/j.1365-2036.2004.02270.x
    • Forrest K, Symmons D, Foster P. Systematic review: is ingestion of paracetamol or non-steroidal anti-inflammatory drugs associated with exacerbations of inflammatory bowel disease? Aliment Pharmacol Ther 2004;20:1035-43. (Pubitemid 39657936)
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.10 , pp. 1035-1043
    • Forrest, K.1    Symmons, D.2    Foster, P.3
  • 47
    • 0033870071 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs in patients with inflammatory bowel disease
    • DOI 10.1016/S0002-9270(00)01033-9
    • O'Brien J. Nonsteroidal anti-inflammatory drugs in patients with inflammatory bowel disease. Am J Gastroenterol 2000;95:1859-61. (Pubitemid 30629276)
    • (2000) American Journal of Gastroenterology , vol.95 , Issue.8 , pp. 1859-1861
    • O'Brien, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.