The regulation of gene expression during onset of differentiation by nuclear mechanical heterogeneity

Biomaterials

Volumn 35, Issue 8, 2014, Pages 2411-2419

  Talwar, Shefali ^a   Jain, Nikhil ^a,b   Shivashankar, G V ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Global gene expression ; Micro patterns; Nuclear mechanics; Stem cells; Transcription factor compartmentalization

Indexed keywords

CELLULAR DIFFERENTIATION; EMBRYONIC STEM CELLS; MECHANICAL HETEROGENEITY; MICROPATTERNS; NUCLEAR ACCUMULATION; NUCLEAR DEFORMATIONS; PHYSICOCHEMICAL FEATURES; TRANSCRIPTIONAL PROGRAM;

ACETYLATION; PLASTICITY; TRANSCRIPTION; TRANSCRIPTION FACTORS;

STEM CELLS;

HISTONE H3; PROTEIN; PROTEIN MRTF A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; EMBRYO; EMBRYONIC STEM CELL; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PLIABILITY; PRIORITY JOURNAL;

GLOBAL GENE EXPRESSION; MICRO-PATTERNS; NUCLEAR MECHANICS; STEM CELLS; TRANSCRIPTION FACTOR COMPARTMENTALIZATION;

ACETYLATION; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL NUCLEUS; CELLS, CULTURED; EMBRYONIC STEM CELLS; FIBRONECTINS; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; HUMANS; MICE; MICROARRAY ANALYSIS; MICROSCOPY, CONFOCAL; NUCLEAR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTOME; UP-REGULATION;

EID: 84891738440     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.010     Document Type: Article

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