메뉴 건너뛰기




Volumn 138, Issue 4, 2011, Pages 601-607

What's all the noise about developmental stochasticity?

Author keywords

Gene expression noise; Incomplete penetrance; Population heterogeneity; Signaling; Stem cells; Time lapse microscopy

Indexed keywords

CONFERENCE PAPER; DEVELOPMENTAL BIOLOGY; GENE REGULATORY NETWORK; GENETIC HETEROGENEITY; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; MOUSE EMBRYO; NONHUMAN; PLURIPOTENT STEM CELL; POPULATION GENETICS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; STOCHASTIC MODEL; THEORETICAL MODEL;

EID: 79951520820     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.059923     Document Type: Conference Paper
Times cited : (37)

References (65)
  • 1
    • 84883829346 scopus 로고    scopus 로고
    • Modeling a snap-action, variable-delay switch controlling extrinsic cell death
    • Albeck, J. G., Burke, J. M., Spencer, S. L., Lauffenburger, D. A. and Sorger, P. K. (2008). Modeling a snap-action, variable-delay switch controlling extrinsic cell death. PLoS Biol. 6, 2831-2852.
    • (2008) PLoS Biol. , vol.6 , pp. 2831-2852
    • Albeck, J.G.1    Burke, J.M.2    Spencer, S.L.3    Lauffenburger, D.A.4    Sorger, P.K.5
  • 5
    • 75849159018 scopus 로고    scopus 로고
    • A theory of microtubule catastrophes and their regulation
    • Brun, L., Rupp, B., Ward, J. J. and Nedelec, F. (2009). A theory of microtubule catastrophes and their regulation. Proc. Natl. Acad. Sci. USA 106, 21173-21178.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 21173-21178
    • Brun, L.1    Rupp, B.2    Ward, J.J.3    Nedelec, F.4
  • 6
    • 77952915049 scopus 로고    scopus 로고
    • Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript
    • Canham, M. A., Sharov, A. A., Ko, M. S. and Brickman, J. M. (2010). Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript. PLoS Biol. 8, e1000379.
    • (2010) PLoS Biol. , vol.8
    • Canham, M.A.1    Sharov, A.A.2    Ko, M.S.3    Brickman, J.M.4
  • 8
    • 77954891539 scopus 로고    scopus 로고
    • Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition
    • Cohen, M., Georgiou, M., Stevenson, N. L., Miodownik, M. and Baum, B. (2010a). Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition. Dev. Cell 19, 78-89.
    • (2010) Dev. Cell , vol.19 , pp. 78-89
    • Cohen, M.1    Georgiou, M.2    Stevenson, N.L.3    Miodownik, M.4    Baum, B.5
  • 9
    • 79951537451 scopus 로고    scopus 로고
    • The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell-cell signalling
    • in press
    • Cohen, M., Baum, B. and Miodownik, M. (2010b). The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell-cell signalling. J. R. Soc. Interface (in press).
    • (2010) J. R. Soc. Interface
    • Cohen, M.1    Baum, B.2    Miodownik, M.3
  • 10
    • 0000296912 scopus 로고
    • Statistical fluctuations in autocatalytic reactions
    • Delbrück, M. (1940). Statistical fluctuations in autocatalytic reactions. J. Chem. Phys. 8, 120-124.
    • (1940) J. Chem. Phys. , vol.8 , pp. 120-124
    • Delbrück, M.1
  • 11
    • 42349117524 scopus 로고    scopus 로고
    • Segmental patterning of the vertebrate embryonic axis
    • Dequeant, M. L. and Pourquie, O. (2008). Segmental patterning of the vertebrate embryonic axis. Nat. Rev. Genet. 9, 370-382.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 370-382
    • Dequeant, M.L.1    Pourquie, O.2
  • 12
    • 36749092279 scopus 로고    scopus 로고
    • Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
    • DOI 10.1038/nature06347, PII NATURE06347
    • Dessaud, E., Yang, L. L., Hill, K., Cox, B., Ulloa, F., Ribeiro, A., Mynett, A., Novitch, B. G. and Briscoe, J. (2007). Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature 450, 717-720. (Pubitemid 350207693)
    • (2007) Nature , vol.450 , Issue.7170 , pp. 717-720
    • Dessaud, E.1    Yang, L.L.2    Hill, K.3    Cox, B.4    Ulloa, F.5    Ribeiro, A.6    Mynett, A.7    Novitch, B.G.8    Briscoe, J.9
  • 14
    • 38049095768 scopus 로고    scopus 로고
    • Stochastic patterning in the mouse preimplantation embryo
    • Dietrich, J. E. and Hiiragi, T. (2007). Stochastic patterning in the mouse preimplantation embryo. Development 134, 4219-4231.
    • (2007) Development , vol.134 , pp. 4219-4231
    • Dietrich, J.E.1    Hiiragi, T.2
  • 15
    • 76249112830 scopus 로고    scopus 로고
    • The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate
    • Doupe, D. P., Klein, A. M., Simons, B. D. and Jones, P. H. (2010). The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate. Dev. Cell 18, 317-323.
    • (2010) Dev. Cell , vol.18 , pp. 317-323
    • Doupe, D.P.1    Klein, A.M.2    Simons, B.D.3    Jones, P.H.4
  • 16
    • 60149102751 scopus 로고    scopus 로고
    • Continuous single-cell imaging of blood generation from haemogenic endothelium
    • Eilken, H. M., Nishikawa, S. and Schroeder, T. (2009). Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature 457, 896-900.
    • (2009) Nature , vol.457 , pp. 896-900
    • Eilken, H.M.1    Nishikawa, S.2    Schroeder, T.3
  • 17
    • 77956520011 scopus 로고    scopus 로고
    • Functional roles for noise in genetic circuits
    • Eldar, A. and Elowitz, M. B. (2010). Functional roles for noise in genetic circuits. Nature 467, 167-173.
    • (2010) Nature , vol.467 , pp. 167-173
    • Eldar, A.1    Elowitz, M.B.2
  • 18
    • 66249105640 scopus 로고    scopus 로고
    • Visualisation and quantification of morphogen gradient formation in the zebrafish
    • Harvey, S. A. and Smith, J. C. (2009). Visualisation and quantification of morphogen gradient formation in the zebrafish. PLoS Biol. 7, e1000101.
    • (2009) PLoS Biol. , vol.7
    • Harvey, S.A.1    Smith, J.C.2
  • 21
    • 44449137418 scopus 로고    scopus 로고
    • Computer simulation of emerging asymmetry in the mouse blastocyst
    • DOI 10.1242/dev.014555
    • Honda, H., Motosugi, N., Nagai, T., Tanemura, M. and Hiiragi, T. (2008). Computer simulation of emerging asymmetry in the mouse blastocyst. Development 135, 1407-1414. (Pubitemid 351753631)
    • (2008) Development , vol.135 , Issue.8 , pp. 1407-1414
    • Honda, H.1    Motosugi, N.2    Nagai, T.3    Tanemura, M.4    Hiiragi, T.5
  • 22
    • 70450162700 scopus 로고    scopus 로고
    • Non-genetic heterogeneity of cells in development: More than just noise
    • Huang, S. (2009). Non-genetic heterogeneity of cells in development: more than just noise. Development 136, 3853-3862.
    • (2009) Development , vol.136 , pp. 3853-3862
    • Huang, S.1
  • 23
    • 58149380714 scopus 로고    scopus 로고
    • Regulative feedback in pattern formation: Towards a general relativistic theory of positional information
    • Jaeger, J., Irons, D. and Monk, N. (2008). Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Development 135, 3175-3183.
    • (2008) Development , vol.135 , pp. 3175-3183
    • Jaeger, J.1    Irons, D.2    Monk, N.3
  • 26
    • 77956906135 scopus 로고    scopus 로고
    • Stochastic variation: From single cells to superorganisms
    • Kilfoil, M. L., Lasko, P. and Abouheif, E. (2009). Stochastic variation: from single cells to superorganisms. HFSP J. 3, 379-385.
    • (2009) HFSP J. , vol.3 , pp. 379-385
    • Kilfoil, M.L.1    Lasko, P.2    Abouheif, E.3
  • 29
    • 69249215528 scopus 로고    scopus 로고
    • The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells
    • Kobayashi, T., Mizuno, H., Imayoshi, I., Furusawa, C., Shirahige, K. and Kageyama, R. (2009). The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev. 23, 1870-1875.
    • (2009) Genes Dev. , vol.23 , pp. 1870-1875
    • Kobayashi, T.1    Mizuno, H.2    Imayoshi, I.3    Furusawa, C.4    Shirahige, K.5    Kageyama, R.6
  • 30
    • 77958485383 scopus 로고    scopus 로고
    • Intestinal stem cell replacement follows a pattern of neutral drift
    • Lopez-Garcia, C., Klein, A. M., Simons, B. D. and Winton, D. J. (2010). Intestinal stem cell replacement follows a pattern of neutral drift. Science 330, 822-825.
    • (2010) Science , vol.330 , pp. 822-825
    • Lopez-Garcia, C.1    Klein, A.M.2    Simons, B.D.3    Winton, D.J.4
  • 31
    • 41749107942 scopus 로고    scopus 로고
    • Stochasticity and cell fate
    • DOI 10.1126/science.1147888
    • Losick, R. and Desplan, C. (2008). Stochasticity and cell fate. Science 320, 65-68. (Pubitemid 351490752)
    • (2008) Science , vol.320 , Issue.5872 , pp. 65-68
    • Losick, R.1    Desplan, C.2
  • 32
    • 64549144670 scopus 로고    scopus 로고
    • Programming with models: Modularity and abstraction provide powerful capabilities for systems biology
    • Mallavarapu, A., Thomson, M., Ullian, B. and Gunawardena, J. (2009). Programming with models: modularity and abstraction provide powerful capabilities for systems biology. J. R. Soc. Interface 6, 257-270.
    • (2009) J. R. Soc. Interface , vol.6 , pp. 257-270
    • Mallavarapu, A.1    Thomson, M.2    Ullian, B.3    Gunawardena, J.4
  • 35
    • 77649140924 scopus 로고    scopus 로고
    • Methylation of H3K4 Is required for inheritance of active transcriptional states
    • Muramoto, T., Muller, I., Thomas, G., Melvin, A. and Chubb, J. R. (2010). Methylation of H3K4 Is required for inheritance of active transcriptional states. Curr. Biol. 20, 397-406.
    • (2010) Curr. Biol. , vol.20 , pp. 397-406
    • Muramoto, T.1    Muller, I.2    Thomas, G.3    Melvin, A.4    Chubb, J.R.5
  • 36
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34- Low/negative hematopoietic stem cell
    • Osawa, M., Hanada, K., Hamada, H. and Nakauchi, H. (1996). Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273, 242-245. (Pubitemid 26285891)
    • (1996) Science , vol.273 , Issue.5272 , pp. 242-245
    • Osawa, M.1    Hanada, K.-I.2    Hamada, H.3    Nakauchi, H.4
  • 39
    • 39249085658 scopus 로고    scopus 로고
    • Live analysis of endodermal layer formation identifies random walk as a novel gastrulation movement
    • Pezeron, G., Mourrain, P., Courty, S., Ghislain, J., Becker, T. S., Rosa, F. M. and David, N. B. (2008). Live analysis of endodermal layer formation identifies random walk as a novel gastrulation movement. Curr. Biol. 18, 276-281.
    • (2008) Curr. Biol. , vol.18 , pp. 276-281
    • Pezeron, G.1    Mourrain, P.2    Courty, S.3    Ghislain, J.4    Becker, T.S.5    Rosa, F.M.6    David, N.B.7
  • 40
    • 58149118293 scopus 로고    scopus 로고
    • Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst
    • Plusa, B., Piliszek, A., Frankenberg, S., Artus, J. and Hadjantonakis, A. K. (2008). Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development 135, 3081-3091.
    • (2008) Development , vol.135 , pp. 3081-3091
    • Plusa, B.1    Piliszek, A.2    Frankenberg, S.3    Artus, J.4    Hadjantonakis, A.K.5
  • 41
    • 67749098104 scopus 로고    scopus 로고
    • Chlamydomonas swims with two 'gears' in a eukaryotic version of run-andtumble locomotion
    • Polin, M., Tuval, I., Drescher, K., Gollub, J. P. and Goldstein, R. E. (2009). Chlamydomonas swims with two 'gears' in a eukaryotic version of run-andtumble locomotion. Science 325, 487-490.
    • (2009) Science , vol.325 , pp. 487-490
    • Polin, M.1    Tuval, I.2    Drescher, K.3    Gollub, J.P.4    Goldstein, R.E.5
  • 42
    • 53549123008 scopus 로고    scopus 로고
    • Nature, nurture, or chance: Stochastic gene expression and its consequences
    • Raj, A. and van Oudenaarden, A. (2008). Nature, nurture, or chance: stochastic gene expression and its consequences. Cell 135, 216-226.
    • (2008) Cell , vol.135 , pp. 216-226
    • Raj, A.1    Van Oudenaarden, A.2
  • 44
    • 77249114260 scopus 로고    scopus 로고
    • Variability in gene expression underlies incomplete penetrance
    • Raj, A., Rifkin, S. A., Andersen, E. and van Oudenaarden, A. (2010). Variability in gene expression underlies incomplete penetrance. Nature 463, 913-918.
    • (2010) Nature , vol.463 , pp. 913-918
    • Raj, A.1    Rifkin, S.A.2    Andersen, E.3    Van Oudenaarden, A.4
  • 45
    • 38049045708 scopus 로고    scopus 로고
    • Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo
    • Ralston, A. and Rossant, J. (2008). Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. Dev. Biol. 313, 614-629.
    • (2008) Dev. Biol. , vol.313 , pp. 614-629
    • Ralston, A.1    Rossant, J.2
  • 46
    • 78650821701 scopus 로고    scopus 로고
    • Planar polarized actomyosin contractile flows control epithelial junction remodelling
    • in press
    • Rauzi, M., Lenne, P. F. and Lecuit, T. (2010). Planar polarized actomyosin contractile flows control epithelial junction remodelling. Nature (in press)
    • (2010) Nature
    • Rauzi, M.1    Lenne, P.F.2    Lecuit, T.3
  • 47
    • 77953766440 scopus 로고    scopus 로고
    • Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: The role of negative feedback
    • Ribes, V. and Briscoe, J. (2009). Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback. Cold Spring Harb. Perspect. Biol. 1, a002014.
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1
    • Ribes, V.1    Briscoe, J.2
  • 48
    • 34848818078 scopus 로고    scopus 로고
    • Synchrony dynamics during initiation, failure, and rescue of the segmentation clock
    • Riedel-Kruse, I. H., Muller, C. and Oates, A. C. (2007). Synchrony dynamics during initiation, failure, and rescue of the segmentation clock. Science 317, 1911-1915.
    • (2007) Science , vol.317 , pp. 1911-1915
    • Riedel-Kruse, I.H.1    Muller, C.2    Oates, A.C.3
  • 50
    • 2342582603 scopus 로고
    • Über die Variabilität in der Manifestierung eines erblichen Merkmales (Abdomen abnormalis) bei Drosophila funebris F
    • Romaschoff, D. D. (1925). Über die Variabilität in der Manifestierung eines erblichen Merkmales (Abdomen abnormalis) bei Drosophila funebris F. Journal für Psychologie und Neurologie. 31, 323-325.
    • (1925) Journal für Psychologie und Neurologie , vol.31 , pp. 323-325
    • Romaschoff, D.D.1
  • 51
    • 38348998668 scopus 로고    scopus 로고
    • Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus
    • Saka, Y., Hagemann, A. I., Piepenburg, O. and Smith, J. C. (2007). Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. Development 134, 4209-4218.
    • (2007) Development , vol.134 , pp. 4209-4218
    • Saka, Y.1    Hagemann, A.I.2    Piepenburg, O.3    Smith, J.C.4
  • 52
    • 77449093887 scopus 로고    scopus 로고
    • Hematopoietic stem cell heterogeneity: Subtypes, not unpredictable behavior
    • Schroeder, T. (2010). Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell Stem Cell 6, 203-207.
    • (2010) Cell Stem Cell , vol.6 , pp. 203-207
    • Schroeder, T.1
  • 53
    • 79957538412 scopus 로고    scopus 로고
    • Segment number and axial identity in a segmentation clock period mutant
    • Schroter, C. and Oates, A. C. (2010). Segment number and axial identity in a segmentation clock period mutant. Curr. Biol. 20, 1254-1258.
    • (2010) Curr. Biol. , vol.20 , pp. 1254-1258
    • Schroter, C.1    Oates, A.C.2
  • 55
    • 66249136447 scopus 로고    scopus 로고
    • Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
    • Spencer, S. L., Gaudet, S., Albeck, J. G., Burke, J. M. and Sorger, P. K. (2009). Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459, 428-432.
    • (2009) Nature , vol.459 , pp. 428-432
    • Spencer, S.L.1    Gaudet, S.2    Albeck, J.G.3    Burke, J.M.4    Sorger, P.K.5
  • 56
    • 0017185026 scopus 로고
    • Non-genetic individuality: Chance in the single cell
    • Spudich, J. L. and Koshland, D. E., Jr (1976). Non-genetic individuality: chance in the single cell. Nature 262, 467-471.
    • (1976) Nature , vol.262 , pp. 467-471
    • Spudich, J.L.1    Koshland Jr., D.E.2
  • 57
    • 76449108997 scopus 로고    scopus 로고
    • Digital nature of the immediate-early transcriptional response
    • Stevense, M., Muramoto, T., Muller, I. and Chubb, J. R. (2010). Digital nature of the immediate-early transcriptional response. Development 137, 579-584.
    • (2010) Development , vol.137 , pp. 579-584
    • Stevense, M.1    Muramoto, T.2    Muller, I.3    Chubb, J.R.4
  • 58
    • 0005952601 scopus 로고
    • Über den Einfluss des Genotypus auf das phänotypen Auftreten eines einzelnes Gens
    • Timoféeff-Ressovsky, N. W. (1925). Über den Einfluss des Genotypus auf das phänotypen Auftreten eines einzelnes Gens. Journal für Psychologie und Neurologie. 31, 305-310.
    • (1925) Journal für Psychologie und Neurologie , vol.31 , pp. 305-310
    • Timoféeff-Ressovsky, N.W.1
  • 59
    • 51149203927 scopus 로고
    • Canalization of development and the inheritance of acquired characters
    • Waddington, C. H. (1942). Canalization of development and the inheritance of acquired characters. Nature 150, 563-565.
    • (1942) Nature , vol.150 , pp. 563-565
    • Waddington, C.H.1
  • 60
    • 4644268320 scopus 로고    scopus 로고
    • At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation
    • DOI 10.1016/j.ydbio.2004.06.026, PII S0012160604005408
    • Wang, Z. and Jaenisch, R. (2004). At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation. Dev. Biol. 275, 192-201. (Pubitemid 39298184)
    • (2004) Developmental Biology , vol.275 , Issue.1 , pp. 192-201
    • Wang, Z.1    Jaenisch, R.2
  • 62
    • 0014593403 scopus 로고
    • Positional information and the spatial pattern of cellular differentiation
    • Wolpert, L. (1969). Positional information and the spatial pattern of cellular differentiation. J. Theor. Biol. 25, 1-47.
    • (1969) J. Theor. Biol. , vol.25 , pp. 1-47
    • Wolpert, L.1
  • 63
    • 76449083746 scopus 로고    scopus 로고
    • FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst
    • Yamanaka, Y., Lanner, F. and Rossant, J. (2010). FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development 137, 715-724.
    • (2010) Development , vol.137 , pp. 715-724
    • Yamanaka, Y.1    Lanner, F.2    Rossant, J.3
  • 64
    • 77954865079 scopus 로고    scopus 로고
    • Polarity in stem cell division: Asymmetric stem cell division in tissue homeostasis
    • Yamashita, Y. M., Yuan, H., Cheng, J. and Hunt, A. J. (2010). Polarity in stem cell division: asymmetric stem cell division in tissue homeostasis. Cold Spring Harb. Perspect. Biol. 2, a001313.
    • (2010) Cold Spring Harb. Perspect. Biol. , vol.2
    • Yamashita, Y.M.1    Yuan, H.2    Cheng, J.3    Hunt, A.J.4
  • 65
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • DOI 10.1038/nature06968, PII NATURE06968
    • Ying, Q. L., Wray, J., Nichols, J., Batlle-Morera, L., Doble, B., Woodgett, J., Cohen, P. and Smith, A. (2008). The ground state of embryonic stem cell self-renewal. Nature 453, 519-523. (Pubitemid 351733324)
    • (2008) Nature , vol.453 , Issue.7194 , pp. 519-523
    • Ying, Q.-L.1    Wray, J.2    Nichols, J.3    Batlle-Morera, L.4    Doble, B.5    Woodgett, J.6    Cohen, P.7    Smith, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.