Grass tablet sublingual immunotherapy downregulates the TH2 cytokine response followed by regulatory T-cell generation

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 1, 2014, Pages

  Suárez Fueyo, Abel ^a   Ramos, Tania ^b   Galán, Agustín ^c   Jimeno, Lucia ^c   Wurtzen, Peter A ^c   Marin, Alicia ^c   De Frutos, Consolación ^b   Blanco, Carlos ^b   Carrera, Ana C ^a   Barber, Domingo ^c   Varona, Rosa ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^c ALK ABELLÓ   (Denmark)

Author keywords

allergic rhinitis; IgE; IL 4; regulatory T cells; Sublingual immunotherapy

Indexed keywords

GRASS POLLEN EXTRACT; GRASS POLLEN VACCINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; INTERLEUKIN 4;

ADULT; ALLERGIC RHINITIS; ANTIBODY PRODUCTION; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CELL LINE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE EXACERBATION; DOWN REGULATION; FLOW CYTOMETRY; GRASS POLLEN; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOPHENOTYPING; LONGITUDINAL STUDY; PHENOTYPE; PRICK TEST; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RHINOCONJUNCTIVITIS; SKIN; SUBLINGUAL IMMUNOTHERAPY; TH1 CELL; TH2 CELL;

ALLERGEN-SPECIFIC IGE; ALLERGEN-SPECIFIC IGG; ALLERGIC RHINITIS; CTLA-4; CYTOTOXIC T LYMPHOCYTE-ASSOCIATED ANTIGEN 4; GPS; GRASS POLLEN SEASON; IGE; IGE-FAB; IGE-FACILITATED ANTIGEN BINDING; IGG(4); IL-4; INDUCED REGULATORY T; ITREG; REGULATORY T; REGULATORY T CELLS; SIGE; SIGG; SLIT; SUBLINGUAL IMMUNOTHERAPY; TREG;

ADULT; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, HUMORAL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOMODULATION; INTERLEUKIN-4; PHLEUM; PLANT EXTRACTS; RHINITIS, ALLERGIC, SEASONAL; SUBLINGUAL IMMUNOTHERAPY; T-LYMPHOCYTES, REGULATORY; TABLETS; TH1 CELLS; TH2 CELLS;

EID: 84891735552     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.09.043     Document Type: Article

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