The induced regulatory T cell level, defined as the proportion of IL-10Foxp3+ cells among CD25+CD4+ leukocytes, is a potential therapeutic biomarker for sublingual immunotherapy: A preliminary report

International Archives of Allergy and Immunology

Volumn 153, Issue 4, 2010, Pages 378-387

  Fujimura, Takashi ^a   Yonekura, Syuji ^a   Taniguchi, Yuriko ^a   Horiguchi, Shigetoshi ^a   Saito, Akemi ^b   Yasueda, Hiroshi ^b   Nakayama, Toshinori ^a   Takemori, Toshitada ^d   Taniguchi, Masaru ^d   Sakaguchi, Masahiro ^c   Okamoto, Yoshitaka ^a  

^a CHIBA UNIVERSITY   (Japan)

^b SAGAMIHARA NATIONAL HOSPITAL   (Japan)

^c AZABU UNIVERSITY   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Allergic rhinitis; Biomarker; Foxp3; Immunotherapy; Interleukin 10; Japanese cedar; Pollinosis; Regulatory T cell; Sublingual immunotherapy

Indexed keywords

BIOLOGICAL MARKER; CRY J 1; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; POLLEN ANTIGEN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD SAMPLING; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; JAPANESE CEDAR; MALE; OPEN STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHARYNX DISCOMFORT; POLLEN ALLERGY; PRIORITY JOURNAL; PRURITUS; QUALITY OF LIFE; QUESTIONNAIRE; REGULATORY T LYMPHOCYTE; SYMPTOM; UPREGULATION;

ADMINISTRATION, SUBLINGUAL; ADULT; ANTIGENS, CD4; ANTIGENS, PLANT; BIOMARKERS, PHARMACOLOGICAL; CELL COUNT; CELLS, CULTURED; CRYPTOMERIA; DESENSITIZATION, IMMUNOLOGIC; DISEASE PROGRESSION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MIDDLE AGED; PLANT PROTEINS; RHINITIS, ALLERGIC, SEASONAL; T-LYMPHOCYTES, REGULATORY;

EID: 77953576589     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000316349     Document Type: Article

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