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Volumn 15, Issue 7, 2013, Pages

Treatment resistant depression: Strategies for primary care topical collection on psychiatry in primary care

Author keywords

Antidepressant switch; Antidepressants; Augmentation; Combination therapy; Complementary and alternative therapy; Depression; Primary care; Psychiatry; Psychotherapy; Treatment resistant depression

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; BUSPIRONE; CITALOPRAM; DESIPRAMINE; FLUOXETINE; LITHIUM SALT; METHYLFOLATE; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NATURAL PRODUCT; NORTRIPTYLINE; OLANZAPINE; PLACEBO; QUETIAPINE; RISPERIDONE; S ADENOSYLMETHIONINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; VENLAFAXINE; ZIPRASIDONE; NEUROLEPTIC AGENT;

EID: 84891715268     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-013-0370-7     Document Type: Article
Times cited : (16)

References (31)
  • 1
    • 33751338530 scopus 로고    scopus 로고
    • Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR D report
    • 17074942 10.1176/appi.ajp.163.11.1905
    • Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR D report. Am J Psychiatry. 2006;163(11):1905-17.
    • (2006) Am J Psychiatry , vol.163 , Issue.11 , pp. 1905-1917
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Stewart, J.W.5    Warden, D.6
  • 2
    • 84857726763 scopus 로고    scopus 로고
    • Sponsorship, antidepressant dose, and outcome in major depressive disorder: Meta-analysis of randomized controlled trials
    • 22401489 10.4088/JCP.11r07204 1:CAS:528:DC%2BC38XlsFChsLw%3D This meta-analysis of antidepressant clinical trials identified a problem with inadequate dosing of comparator medications in industry-sponsored studies, using consensus dosing guidelines. The analysis found underdosing of the comparison medication in 37% of trials, while in only 5% was the sponsors medication underdosed
    • • Sinyor M, Schaffer A, Smart KA, Levitt AJ, Lanctot KL, Grysman NH. Sponsorship, antidepressant dose, and outcome in major depressive disorder: Meta-analysis of randomized controlled trials. J Clin Psychiatry. 2012;73(2):e277-87. This meta-analysis of antidepressant clinical trials identified a problem with inadequate dosing of comparator medications in industry-sponsored studies, using consensus dosing guidelines. The analysis found underdosing of the comparison medication in 37% of trials, while in only 5% was the sponsors medication underdosed.
    • (2012) J Clin Psychiatry , vol.73 , Issue.2 , pp. 277-287
    • Sinyor, M.1    Schaffer, A.2    Smart, K.A.3    Levitt, A.J.4    Lanctot, K.L.5    Grysman, N.H.6
  • 3
    • 33751092538 scopus 로고    scopus 로고
    • Nontricyclic antidepressants: Predictors of nonadherence
    • 1:CAS:528:DC%2BD28Xht1Smt7nI
    • Brook OH, van Hout HP, Stalman WA, de Haan M. Nontricyclic antidepressants: Predictors of nonadherence. J ClinPsychopharmacol. 2006;26(6):643-7.
    • (2006) J ClinPsychopharmacol , vol.26 , Issue.6 , pp. 643-647
    • Brook, O.H.1    Van Hout, H.P.2    Stalman, W.A.3    De Haan, M.4
  • 4
    • 78650841139 scopus 로고    scopus 로고
    • If at first you don't succeed: A review of the evidence for antidepressant augmentation, combination and switching strategies
    • •• Connolly KR, Thase ME. If at first you don't succeed: A review of the evidence for antidepressant augmentation, combination and switching strategies. Drugs. 2011;71(1):43-64. This is a comprehensive review of treatment alternatives in face of inadequate initial antidepressant response, including switching, augmentation, and antidepressant combinations.
    • (2011) Drugs , vol.71 , Issue.1 , pp. 43-64
    • Connolly, K.R.1    Thase, M.E.2
  • 5
    • 77950385461 scopus 로고    scopus 로고
    • The sequenced treatment alternatives to relieve depression (STARD) trial: A review
    • Sinyor M, Schaffer A, Levitt A. The sequenced treatment alternatives to relieve depression (STARD) trial: A review. Can J Psychiatr Rev Can Psychiatr. 2010;55(3):126-35.
    • (2010) Can J Psychiatr Rev Can Psychiatr , vol.55 , Issue.3 , pp. 126-135
    • Sinyor, M.1    Schaffer, A.2    Levitt, A.3
  • 6
    • 84855343817 scopus 로고    scopus 로고
    • Treating depression after initial treatment failure: Directly comparing switch and augmenting strategies in STARD
    • 22198447 10.1097/JCP.0b013e31823f705d
    • Gaynes BN, Dusetzina SB, Ellis AR, Hansen RA, Farley JF, Miller WC, et al. Treating depression after initial treatment failure: Directly comparing switch and augmenting strategies in STARD. J Clin Psychopharmacol. 2012;32(1):114-9.
    • (2012) J Clin Psychopharmacol , vol.32 , Issue.1 , pp. 114-119
    • Gaynes, B.N.1    Dusetzina, S.B.2    Ellis, A.R.3    Hansen, R.A.4    Farley, J.F.5    Miller, W.C.6
  • 7
    • 84857357467 scopus 로고    scopus 로고
    • Risk of adverse events in treatment-resistant depression: Propensity-score-matched comparison of antidepressant augment and switch strategies
    • 22079151 10.1016/j.genhosppsych.2011.10.001
    • Hansen RA, Dusetzina SB, Ellis AR, Sturmer T, Farley JF, Gaynes BN. Risk of adverse events in treatment-resistant depression: Propensity-score-matched comparison of antidepressant augment and switch strategies. Gen Hosp Psychiatry. 2012;34(2):192-200.
    • (2012) Gen Hosp Psychiatry , vol.34 , Issue.2 , pp. 192-200
    • Hansen, R.A.1    Dusetzina, S.B.2    Ellis, A.R.3    Sturmer, T.4    Farley, J.F.5    Gaynes, B.N.6
  • 8
    • 0033007725 scopus 로고    scopus 로고
    • A placebo-controlled comparison of the antidepressant efficacy and effects on sexual functioning of sustained-release bupropion and sertraline
    • 10363731 10.1016/S0149-2918(00)88317-4 1:CAS:528:DyaK1MXjsl2mt7w%3D
    • Croft H, Settle Jr E, Houser T, Batey SR, Donahue RM, Ascher JA. A placebo-controlled comparison of the antidepressant efficacy and effects on sexual functioning of sustained-release bupropion and sertraline. Clin Ther. 1999;21(4):643-58.
    • (1999) Clin Ther , vol.21 , Issue.4 , pp. 643-658
    • Croft, H.1    Settle, Jr.E.2    Houser, T.3    Batey, S.R.4    Donahue, R.M.5    Ascher, J.A.6
  • 9
    • 81255209348 scopus 로고    scopus 로고
    • Does the presence of accompanying symptom clusters differentiate the comparative effectiveness of second-line medication strategies for treating depression?
    • 21898717 10.1002/da.20898
    • Gaynes BN, Farley JF, Dusetzina SB, Ellis AR, Hansen RA, Miller WC, et al. Does the presence of accompanying symptom clusters differentiate the comparative effectiveness of second-line medication strategies for treating depression? Depress Anxiety. 2011;28(11):989-98.
    • (2011) Depress Anxiety , vol.28 , Issue.11 , pp. 989-998
    • Gaynes, B.N.1    Farley, J.F.2    Dusetzina, S.B.3    Ellis, A.R.4    Hansen, R.A.5    Miller, W.C.6
  • 10
    • 0036322270 scopus 로고    scopus 로고
    • Double-blind study of high-dose fluoxetine versus lithium or desipramine augmentation of fluoxetine in partial responders and nonresponders to fluoxetine
    • 10.1097/00004714-200208000-00008 1:CAS:528:DC%2BD38XmsFagsrs%3D
    • Fava M, Alpert J, Nierenberg A, Lagomasino I, Sonawalla S, Tedlow J, et al. Double-blind study of high-dose fluoxetine versus lithium or desipramine augmentation of fluoxetine in partial responders and nonresponders to fluoxetine. J ClinPsychopharmacol. 2002;22(4):379-87.
    • (2002) J ClinPsychopharmacol , vol.22 , Issue.4 , pp. 379-387
    • Fava, M.1    Alpert, J.2    Nierenberg, A.3    Lagomasino, I.4    Sonawalla, S.5    Tedlow, J.6
  • 11
    • 45349107889 scopus 로고    scopus 로고
    • Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines
    • 18413657 10.1177/0269881107088441 1:CAS:528:DC%2BD1cXhtValt7jF
    • Anderson IM, Ferrier IN, Baldwin RC, Cowen PJ, Howard L, Lewis G, et al. Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol. 2008;22(4):343-96.
    • (2008) J Psychopharmacol , vol.22 , Issue.4 , pp. 343-396
    • Anderson, I.M.1    Ferrier, I.N.2    Baldwin, R.C.3    Cowen, P.J.4    Howard, L.5    Lewis, G.6
  • 12
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STARD: Implications for clinical practice
    • Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STARD: Implications for clinical practice. AmJPsychiatry. 2006;163(1):28-40.
    • (2006) AmJPsychiatry , vol.163 , Issue.1 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Warden, D.5    Ritz, L.6
  • 13
    • 74949137041 scopus 로고    scopus 로고
    • Therapeutic options for treatment-resistant depression
    • 20088620 10.2165/11530280-000000000-00000 1:CAS:528:DC%2BC3cXktlSrtbw%3D
    • Shelton RC, Osuntokun O, Heinloth AN, Corya SA. Therapeutic options for treatment-resistant depression. CNS Drugs. 2010;24(2):131-61.
    • (2010) CNS Drugs , vol.24 , Issue.2 , pp. 131-161
    • Shelton, R.C.1    Osuntokun, O.2    Heinloth, A.N.3    Corya, S.A.4
  • 14
    • 1642523483 scopus 로고    scopus 로고
    • Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: A double-blind, randomized study
    • 14744472 10.1016/j.biopsych.2003.08.007 1:CAS:528:DC%2BD2cXmvF2mtg%3D%3D
    • Nelson JC, Maiure CM, Jatlow PI, Bowers MB, Price LH. Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: A double-blind, randomized study. Biol Psychiatry. 2004;55(3):296-300.
    • (2004) Biol Psychiatry , vol.55 , Issue.3 , pp. 296-300
    • Nelson, J.C.1    Maiure, C.M.2    Jatlow, P.I.3    Bowers, M.B.4    Price, L.H.5
  • 15
    • 0025829243 scopus 로고
    • A preliminary, open study of the combination of fluoxetine and desipramine for rapid treatment of major depression
    • 2009031 10.1001/archpsyc.1991.01810280019002 1:STN:280: DyaK3M7otF2nsg%3D%3D
    • Nelson JC, Mazure CM, Bowers Jr MB, Jatlow PI. A preliminary, open study of the combination of fluoxetine and desipramine for rapid treatment of major depression. Arch Gen Psychiatry. 1991;48(4):303-7.
    • (1991) Arch Gen Psychiatry , vol.48 , Issue.4 , pp. 303-307
    • Nelson, J.C.1    Mazure, C.M.2    Bowers, Jr.M.B.3    Jatlow, P.I.4
  • 16
    • 85047700549 scopus 로고    scopus 로고
    • What happened to lithium? Antidepressant augmentation in clinical settings
    • 16816227 10.1176/appi.ajp.163.7.1219
    • Valenstein M, McCarthy JF, Austin KL, Greden JF, Young EA, Blow FC. What happened to lithium? Antidepressant augmentation in clinical settings. Am J Psychiatry. 2006;163(7):1219-25.
    • (2006) Am J Psychiatry , vol.163 , Issue.7 , pp. 1219-1225
    • Valenstein, M.1    McCarthy, J.F.2    Austin, K.L.3    Greden, J.F.4    Young, E.A.5    Blow, F.C.6
  • 17
    • 0037081445 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of antidepressant augmentation with mirtazapine
    • 11822997 10.1016/S0006-3223(01)01262-8 1:CAS:528:DC%2BD38Xos1CitA%3D%3D
    • Carpenter LL, Yasmin S, Price LH. A double-blind, placebo-controlled study of antidepressant augmentation with mirtazapine. Biol Psychiatry. 2002;51(2):183-8.
    • (2002) Biol Psychiatry , vol.51 , Issue.2 , pp. 183-188
    • Carpenter, L.L.1    Yasmin, S.2    Price, L.H.3
  • 18
    • 0037310632 scopus 로고    scopus 로고
    • A prospective trial of bupropion sr augmentation of partial and non-responders to serotonergic antidepressants
    • 12544372 10.1097/00004714-200302000-00005 1:CAS:528: DC%2BD3sXmsVSnuw%3D%3D
    • DeBattista C, Solvason HB, Poirier J, Kendrick E, Schatzberg AF. A prospective trial of bupropion sr augmentation of partial and non-responders to serotonergic antidepressants. J Clin Psychopharmacol. 2003;23(1):27-30.
    • (2003) J Clin Psychopharmacol , vol.23 , Issue.1 , pp. 27-30
    • Debattista, C.1    Solvason, H.B.2    Poirier, J.3    Kendrick, E.4    Schatzberg, A.F.5
  • 20
    • 9344237128 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: A clinical, pharmacokinetic, and pharmacogenetic investigation
    • 8835706 10.1097/00004714-199608000-00006 1:STN:280:DyaK28vjt1Kmtg%3D%3D
    • Baumann P, Nil R, Souche A, Montaldi S, Baettig D, Lambert S, et al. A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: A clinical, pharmacokinetic, and pharmacogenetic investigation. J Clin Psychopharmacol. 1996;16(4):307-14.
    • (1996) J Clin Psychopharmacol , vol.16 , Issue.4 , pp. 307-314
    • Baumann, P.1    Nil, R.2    Souche, A.3    Montaldi, S.4    Baettig, D.5    Lambert, S.6
  • 21
    • 84871824309 scopus 로고    scopus 로고
    • Lmethylfolate as adjunctive therapy for SSRIresistant major depression: Results of two randomized, doubleblind, parallelsequential trials
    • This paper reports was the first two doubleblind placebocontrolled clinical trials of lmethylfolate augmentation of SSRIs in treatment resistant patients. The first trial of 7.5 mg combination therapy did not separate from placebo. However, the second 15 mg augmentation was significantly better than placebo combination. These studies used a novel trial design called the sequential parallel comparison design (SPCD) which maximizes the ability to detect significant differences with relatively small sample sizes. For a more complete discussion of this method see Boessen R., Knol M., Groenwold R., Grobbee D., Roes K.: Increasing trial efficiency by early reallocation of placebo nonresponders in sequential parallel comparison designs: Application to antidepressant trials; Clin Trials 2012;9:578-587 and
    • •• Papakostas GI, Shelton RC, Zajecka JM, Etemad B, Rickels K, Clain A, et al. Lmethylfolate as adjunctive therapy for SSRIresistant major depression: results of two randomized, doubleblind, parallelsequential trials. Am J Psychiatry. 2012;169:1267-74. This paper reports was the first two doubleblind placebocontrolled clinical trials of lmethylfolate augmentation of SSRIs in treatment resistant patients. The first trial of 7.5 mg combination therapy did not separate from placebo. However, the second 15 mg augmentation was significantly better than placebo combination. These studies used a novel trial design called the sequential parallel comparison design (SPCD) which maximizes the ability to detect significant differences with relatively small sample sizes. For a more complete discussion of this method see Boessen R., Knol M., Groenwold R., Grobbee D., Roes K.: Increasing trial efficiency by early reallocation of placebo nonresponders in sequential parallel comparison designs: Application to antidepressant trials; Clin Trials 2012;9:578-587 and http://www.rctlogic.com/clinicaltrial/design.aspx.
    • (2012) Am J Psychiatry , vol.169 , pp. 1267-1274
    • Papakostas, G.I.1    Shelton, R.C.2    Zajecka, J.M.3    Etemad, B.4    Rickels, K.5    Clain, A.6
  • 22
    • 77953789279 scopus 로고    scopus 로고
    • Complementary and alternative medicine in major depressive disorder: The american psychiatric association task force report
    • 10.4088/JCP.10cs05959blu 1:CAS:528:DC%2BC3cXpt1Oksbs%3D This is an excellent, comprehensive review of complementary and alternative medicine options for depression. The paper reviews omega-3 fatty acids, s-adenosylmethionine (SAMe), st. John's Wort, folate, bright light therapy, acupuncture, exercise, mindfulness-based cognitive therapy, problem-solving therapy, and well-being therapy. This is an excellent teaching paper that reviews a wide range of non-pharmaceutical approaches for depression
    • •• Freeman MP, Fava M, Lake J, Trivedi MH, Wisner KL, Mischoulon D. Complementary and alternative medicine in major depressive disorder: The american psychiatric association task force report. J ClinPsychiatry. 2010;71(6):669-81. This is an excellent, comprehensive review of complementary and alternative medicine options for depression. The paper reviews omega-3 fatty acids, s-adenosylmethionine (SAMe), st. John's Wort, folate, bright light therapy, acupuncture, exercise, mindfulness-based cognitive therapy, problem-solving therapy, and well-being therapy. This is an excellent teaching paper that reviews a wide range of non-pharmaceutical approaches for depression.
    • (2010) J ClinPsychiatry , vol.71 , Issue.6 , pp. 669-681
    • Freeman, M.P.1    Fava, M.2    Lake, J.3    Trivedi, M.H.4    Wisner, K.L.5    Mischoulon, D.6
  • 23
    • 8744287602 scopus 로고    scopus 로고
    • S-adenosyl-l-methionine (same) as an adjunct for resistant major depressive disorder: An open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine
    • 10.1097/01.jcp.0000145339.45794.cd 1:CAS:528:DC%2BD2cXpsF2nsbk%3D
    • Alpert JE, Papakostas G, Mischoulon D, Worthington III JJ, Petersen T, Mahal Y, et al. S-adenosyl-l-methionine (same) as an adjunct for resistant major depressive disorder: An open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine. J ClinPsychopharmacol. 2004;24(6):661-4.
    • (2004) J ClinPsychopharmacol , vol.24 , Issue.6 , pp. 661-664
    • Alpert, J.E.1    Papakostas, G.2    Mischoulon, D.3    Worthington III, J.J.4    Petersen, T.5    Mahal, Y.6
  • 24
    • 77955360283 scopus 로고    scopus 로고
    • S-adenosyl methionine (same) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: A double-blind, randomized clinical trial
    • 20595412 10.1176/appi.ajp.2009.09081198 This is the one double-blind, placebo controlled study of SAMe (800 mg. twice per day) as an add-on therapy for depressed patients who experienced insufficient response to any of several SSRI's. The HAM-D response and remission rates were higher for SAMe-treated patients (36.1% and 25.8%, respectively) than placebo (17.6% versus 11.7%, respectively). The number needed to treat for response and remission was approximately one in six and one in seven, indicating a moderate effect
    • • Papakostas GI, Mischoulon D, Shyu I, Alpert JE, Fava M. S-adenosyl methionine (same) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: A double-blind, randomized clinical trial. Am J Psychiatry. 2010;167(8):942-8. This is the one double-blind, placebo controlled study of SAMe (800 mg. twice per day) as an add-on therapy for depressed patients who experienced insufficient response to any of several SSRI's. The HAM-D response and remission rates were higher for SAMe-treated patients (36.1% and 25.8%, respectively) than placebo (17.6% versus 11.7%, respectively). The number needed to treat for response and remission was approximately one in six and one in seven, indicating a moderate effect.
    • (2010) Am J Psychiatry , vol.167 , Issue.8 , pp. 942-948
    • Papakostas, G.I.1    Mischoulon, D.2    Shyu, I.3    Alpert, J.E.4    Fava, M.5
  • 25
    • 1542373740 scopus 로고    scopus 로고
    • Lower risk for tardive dyskinesia associated with second-generation antipsychotics: A systematic review of 1-year studies
    • 14992963 10.1176/appi.ajp.161.3.414
    • Correll CU, Leucht S, Kane JM. Lower risk for tardive dyskinesia associated with second-generation antipsychotics: A systematic review of 1-year studies. Am J Psychiatry. 2004;161(3):414-25.
    • (2004) Am J Psychiatry , vol.161 , Issue.3 , pp. 414-425
    • Correll, C.U.1    Leucht, S.2    Kane, J.M.3
  • 26
    • 69949087539 scopus 로고    scopus 로고
    • Atypical antipsychotic augmentation in major depressive disorder: A meta-analysis of placebo-controlled randomized trials
    • 19687129 10.1176/appi.ajp.2009.09030312
    • Nelson JC, Papakostas GI. Atypical antipsychotic augmentation in major depressive disorder: A meta-analysis of placebo-controlled randomized trials. Am J Psychiatry. 2009;166(9):980-91.
    • (2009) Am J Psychiatry , vol.166 , Issue.9 , pp. 980-991
    • Nelson, J.C.1    Papakostas, G.I.2
  • 27
    • 34548299095 scopus 로고    scopus 로고
    • Efficacy and tolerability of adjunctive ziprasidone in treatment-resistant depression: A randomized, open-label, pilot study
    • 10.4088/JCP.v68n0714 1:CAS:528:DC%2BD2sXps1Gntbc%3D
    • Dunner DL, Amsterdam JD, Shelton RC, Loebel A, Romano SJ. Efficacy and tolerability of adjunctive ziprasidone in treatment-resistant depression: A randomized, open-label, pilot study. J ClinPsychiatry. 2007;68(7):1071-7.
    • (2007) J ClinPsychiatry , vol.68 , Issue.7 , pp. 1071-1077
    • Dunner, D.L.1    Amsterdam, J.D.2    Shelton, R.C.3    Loebel, A.4    Romano, S.J.5
  • 28
    • 84864851844 scopus 로고    scopus 로고
    • Rockville MD 2011. This is the most comprehensive review of the evidence supporting a wide range of non-pharmacological approaches to depression, including electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), vagus nerve stimulation (VNS), psychotherapies, including cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT). It is available online
    • • Gaynes BN, Lux LJ, Lloyd SW, Hansen RA, Gartlehner G, Keener P, Brode S, Evans TS, Jonas D, Crotty K, Viswanathan M, Lohr KN. Nonpharmacologic interventions for treatment-resistant depression in adults. Rockville MD 2011. This is the most comprehensive review of the evidence supporting a wide range of non-pharmacological approaches to depression, including electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), vagus nerve stimulation (VNS), psychotherapies, including cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT). It is available online: http://www.ncbi.nlm.nih.gov/books/NBK65315/pdf/TOC.pdf.
    • Nonpharmacologic Interventions for Treatment-resistant Depression in Adults
    • Gaynes, B.N.1    Lux, L.J.2    Lloyd, S.W.3    Hansen, R.A.4    Gartlehner, G.5    Keener, P.6    Brode, S.7    Evans, T.S.8    Jonas, D.9    Crotty, K.10    Viswanathan, M.11    Lohr, K.N.12
  • 29
    • 34249686579 scopus 로고    scopus 로고
    • Progressive resistance to a selective serotonin reuptake inhibitor but not to cognitive therapy in the treatment of major depression
    • 10.1037/0022-006X.75.2.267
    • Leykin Y, Amsterdam JD, DeRubeis RJ, Gallop R, Shelton RC, Hollon SD. Progressive resistance to a selective serotonin reuptake inhibitor but not to cognitive therapy in the treatment of major depression. J Consult ClinPsychol. 2007;75(2):267-76.
    • (2007) J Consult ClinPsychol , vol.75 , Issue.2 , pp. 267-276
    • Leykin, Y.1    Amsterdam, J.D.2    Derubeis, R.J.3    Gallop, R.4    Shelton, R.C.5    Hollon, S.D.6
  • 31
    • 0027761898 scopus 로고
    • Patterns of antidepressant use in community practice
    • 1:STN:280:DyaK2c7ls1WmtA%3D%3D
    • Simon GE, VonKorff M, Wagner EH, Barlow W. Patterns of antidepressant use in community practice. Gen HospPsychiatry. 1993;15:399-408.
    • (1993) Gen HospPsychiatry , vol.15 , pp. 399-408
    • Simon, G.E.1    Vonkorff, M.2    Wagner, E.H.3    Barlow, W.4


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