Combining norepinephrine and serotonin reuptake inhibition mechanisms for treatment of depression: A double-blind, randomized study

Biological Psychiatry

Volumn 55, Issue 3, 2004, Pages 296-300

  Nelson, J Craig ^a   Mazure, Carolyn M ^b   Jatlow, Peter I ^b   Bowers Jr , Malcolm B ^b   Price, Lawrence H ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BUTLER HOSPITAL   (United States)

Author keywords

Combined treatment; Efficacy; Major depression; Norepinephrine; Serotonin

Indexed keywords

BENZODIAZEPINE DERIVATIVE; DESIPRAMINE; FLUOXETINE; IMIPRAMINE; NORADRENALIN UPTAKE INHIBITOR; PLACEBO; SEROTONIN UPTAKE INHIBITOR;

ADULT; AGITATION; ANXIETY DISORDER; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; ENZYME INHIBITION; FEMALE; HAMILTON SCALE; HOSPITALIZATION; HUMAN; INFORMED CONSENT; INSOMNIA; MAJOR DEPRESSION; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; REMISSION; STATISTICAL ANALYSIS; TREATMENT OUTCOME;

EID: 1642523483     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2003.08.007     Document Type: Article

References (29)

1. Clinical Practice Guideline: Depression in Primary Care: Treatment of Major Depression. Vol 2. 1993;US Government Printing Office, Rockville, MD.
2. Alexanderson B. Pharmacokinetics of nortriptyline in man after single and multiple oral doses The predictability of steady-state plasma concentrations from single-dose plasma-level data . Eur J Clin Pharmacol. 4:1972;82-91.
3. Baron B.M., Ogen A.M., Siegel B.W., Stegeman J., Ursillo R.C., Dudley M.W. Rapid down-regulation of beta-adrenoceptors by co-administration of desipramine and fluoxetine. Eur J Pharmacol. 154:1988;125-134.
4. Brunswick D.J., Amsterdam J.D., Mendels J., Stern S.L. Prediction of steady-state imipramine and desmethylimpramine plasma concentrations from single dose data. Clin Pharmacol Ther. 25:1979;605-610.
5. Charney D.S., Price L.H., Heninger G.R. Desipramine-yohimbine combination treatment of refractory depression. Arch Gen Psychiatry. 43:1986;1155-1161.
6. Cooper T.B., Simpson G.M. Prediction of individual dosage of nortriptyline. Am J Psychiatry. 135:1978;333-335.
7. Fava M., Rosenbaum J.F., Grossbard S.J., McGrath P.J., Stewart J.W., Amsterdam J.D., Quitkin F.M. Lithium and tricyclic augmentation of fluoxetine treatment for resistant major depression A double blind, controlled study . Am J Psychiatry. 151:1994;1372-1374.
8. Fava M.E., Davidson K.G. Definition and epidemiology of treatment resistant depression. Psychiatr Clin North Am. 19:1996;179-198.
9. First M.B., Gibbon M., Spitzer R.L., et al. Structured Clinical Interview for DSM IV Disorders (SCID II). 1997;American Psychiatric Association Press, Washington, DC.
10. Goldstein D.J., Mallinckrodt C., Lu Y., Demitrack M.A. Duloxetine in the treatment of major depressive disorder A double-blind clinical trial . J Clin Psychiatry. 63:2002;225-231.
11. Guy W. ECDEU Assessment Manual for Psychopharmacology, Revised. 1976;National Institute of Mental Health, Psychopharmacology Research Branch, Rockville, MD.
12. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 23:1960;56-61. 217-222; 313-331.
13. Hyler S.E., Skodol A.E., Kellman H.D., Oldham J.M., Rosnick L. Validity of the personality diagnostic questionnaire-revised Comparison with two structured interviews . Am J Psychiatry. 147:1990;1043-1048.
14. Mazure C., Nelson J.C., Price L.H. Reliability and validity of the symptoms of major depressive illness. Arch Gen Psychiatry. 43:1986;451-456.
15. Montgomery S.A., Asberg M. A new depression rating scale designed to be sensitive to change. Br J Psychiatry. 134:1979;382-389.
16. Nelson J.C. A review of the efficacy of serotonergic and noradrenergic reuptake inhibitors for treatment of major depression. Biol Psychiatry. 46:1999;1301-1308.
17. Nelson J.C., Jatlow P., Quinlan D.M., Bowers M.B. Desipramine plasma concentrations and antidepressant response. Arch Gen Psychiatry. 39:1982;1419-1422.
18. Nelson J.C., Jatlow P.I., Mazure C. Rapid desipramine dose adjustment using 24-hour levels. J Clin Psychopharm. 7:1987;72-77.
19. Nelson J.C., Mazure C.M. A rating scale specific for tricyclic response in melancholia The TRIM . J Clin Psychopharmacol. 10:1990;252-260.
20. Nelson J.C., Mazure C.M., Bowers M.B., Jatlow P.I. A preliminary open study of the combination of fluoxetine and desipramine for rapid treatment of major depression. Arch Gen Psychiatry. 48:1991;303-307.
21. Nelson J.C., Mazure C.M., Jatlow P.I. Characteristics of desipramine-refractory depression. J Clin Psychiatry. 55:1994;12-19.
22. Nelson J.C., Price L.H. Lithium or desipramine augmentation of fluoxetine treatment. Am J Psychiatry. 152:1995;1538-1539. [letter].
23. Potter W.Z., Zavadil A.P., Kopin I.J., Goodwin F.K. Single-dose kinetics predict steady-state concentrations of imipramine and desipramine. Arch Gen Psychiatry. 37:1980;314-320.
24. Proelss H.F., Logman H.J., Miles D.G. High performance liquid chromatographic simultaneous determination of commonly used antidepressants. Clin Chem. 24:1978;1948-1953.
25. Quitkin F.M., Petkova E., McGrath P.J., Taylor B., Beasley C., Stewart J., et al. When should a trial of fluoxetine for major depression be declared failed? Am J Psychiatry. 160:2003;734-740.
26. Seth R., Jennings A.L., Bindman J., Phillips J., Bergmann K. Combination treatment with noradrenaline and serotonin reuptake inhibitors in resistant depression. Br J Psychiatry. 161:1992;562-565.
27. Thase M.E., Entsuah A.R., Rudolph R.L. Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry. 178:2001;234-241.
28. Weilburg J.B., Rosenbaum J.F., Biederman J., Sachs G.S., Pollack M.H., Kelly K. Fluoxetine added to non-MAOI antidepressants converts nonresponders to responders A preliminary report . J Clin Psychiatry. 50:1989;447-449.
29. Zajecka J.M., Jeffries H., Fawcett J. The efficacy of fluoxetine combined with a heterocyclic antidepressant in treatment-resistant depression A retrospective analysis . J Clin Psychiatry. 56:1995;338-343.