Antioxidant supplementation ameliorates molecular deficits in smith-lemli-opitz syndrome

Biological Psychiatry

Volumn 75, Issue 3, 2014, Pages 215-222

  Korade, Zeljka ^a,c   Xu, Libin ^a,b   Harrison, Fiona E ^a,c   Ahsen, Refayat ^a   Hart, Sarah E ^a   Folkes, Oakleigh M ^a   Mirnics, Károly ^a,c   Porter, Ned A ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

7 dehydrocholesterol; Antioxidants; DHCEO; Dhcr7; oxysterol; Smith Lemli Opitz Syndrome

Indexed keywords

3BETA,5ALPHA DIHYDROXYCHOLEST 7 EN 6 ONE; 7 DEHYDROCHOLESTEROL; ALPHA TOCOPHEROL; ANTIOXIDANT; AQUA E; AQUADEKS; ASCORBIC ACID; OXYSTEROL; RETINOL; UBIDECARENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN LEVEL; CELL LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG EFFECT; FEMALE; FIBROBLAST; GENE EXPRESSION REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIPID PEROXIDATION; MALE; MATERNAL NUTRITION; MOUSE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SMITH LEMLI OPITZ SYNDROME; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

7-DEHYDROCHOLESTEROL; ANTIOXIDANTS; DHCEO; DHCR7; OXYSTEROL; SMITH-LEMLI-OPITZ SYNDROME;

ALPHA-TOCOPHEROL; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; ASCORBIC ACID; BRAIN; CELL LINE, TRANSFORMED; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; LIVER; MALE; MICE; MICE, TRANSGENIC; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SMITH-LEMLI-OPITZ SYNDROME; UBIQUINONE;

EID: 84891624823     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.06.013     Document Type: Article

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